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Two-pronged phage treatment counters resistance in Mycobacterium abscessus lung infections

Scientists from A*STAR Infectious Diseases Labs (A*STAR IDL), Nanyang Technological University, Singapore’s Lee Kong Chian School of Medicine (LKCMedicine), the National University of Singapore (NUS), and international collaborators have uncovered how Mycobacterium abscessus—a bacterium that causes serious lung infections—can evade bacteriophage (phage) therapy, and demonstrated a combination strategy to overcome this resistance, offering a pathway toward more effective and durable treatments. The study was published in the Proceedings of the National Academy of Sciences.

Antimicrobial resistance (AMR) is an escalating health challenge that is expected to place growing strain on health care systems worldwide. As AMR continues to erode the effectiveness of existing antibiotics—with one in six bacterial infections worldwide now resistant to antibiotics—scientists are accelerating efforts to develop new countermeasures such as phage therapy, which uses viruses to target bacteria. These efforts are important for strengthening global health and infectious disease preparedness.

The brain may use dopamine to bend time and shape memory

Ever heard of getting a “dopamine hit” from something you enjoy? These exciting moments also appear to influence memory, although perhaps not in the way you’d expect.

New research by UCLA psychologists suggests your brain may use dopamine to distort and expand time between distinct events, separating the flow of experience into pieces that can be flexibly reconstructed in the future.

The study, published in Nature Communications, found that a key dopamine-producing area of the brain—the ventral tegmental area—was activated when volunteers participating in an MRI scan detected the start of a new event. Importantly, when this dopamine hub was strongly activated, people reported more time had passed. The researchers also found that when people blinked more during a new event—an action thought to be related to dopamine signaling—their memory for time once again expanded.

Webb Telescope Reveals Dark Surface of Exoplanet LHS 3844b

Sebastian Zieba: “Since LHS 3,844 b lacks such a silicate crust, one may conclude that Earth-like plate tectonics does not apply to this planet, or it is ineffective. This planet likely only contains little water.”


What do the surfaces of rocky exoplanets look like? This is what a recent study published in Nature Astronomy hopes to address as a team of scientists investigated how heat measurements could be used to ascertain the potential physical and chemical properties of a rocky nearby rocky exoplanet. This study has the potential to help scientists use new methods for studying rocky exoplanets, as they are still too far away to be directly observed.

For the study, the researchers used NASA’s powerful James Webb Space Telescope (JWST) to observe the rocky exoplanet LHS 3,844 b, which is located approximately 49 light-years from Earth and whose mass and radius is estimated to be almost 2.5 and 1.3 times of Earth, respectively. LHS 3,844 b orbits inside the interior edge of its star’s habitable zone, making it analog to Mercury. To accomplish this, the researchers used JWST to obtain heat measurements of LHS 3,844 b to ascertain the exoplanet’s potential physical, geological, and chemical properties.

In the end, the researchers found that LHS 3,844 b is likely comprised of a dark, volcanic surface that’s been weathered by space radiation. The team notes that LHS 3,384 b either has a fresh surface or mimics the Moon or Mercury, the latter of which ceased volcanic activity billions of years ago. The team was also able to potentially rule out a distinct geological characteristic that Earth possesses.

Oldest Moon Craters Are Best Targets for Water Ice

“We found that the earlier a region became shadowed, the larger the area that was able to accumulate ice,” said Dr. Oded Aharonson. [ https://www.labroots.com/trending/space/30512/moon-craters-targets-water-ice-2](https://www.labroots.com/trending/space/30512/moon-craters-targets-water-ice-2)


What are the best places on the Moon to find water ice that can be used for future crewed missions to the Moon’s surface? This is what a recent study published in Nature Astronomy hopes to address as a team of scientists investigated potential regions of the Moon where future astronauts could have the highest chance of finding water ice. This study has the potential to help scientists, engineers, mission planners, and future astronauts narrow the scope for finding the best locations of water ice on the Moon to aid in future crewed missions, thus negating the need for water supplies from Earth.

For the study, the researchers analyze data obtained from the Lyman-Alpha Mapping Project (LAMP), which is an instrument on the Lunar Reconnaissance Orbiter designed to map the entire surface of the Moon in far ultraviolet light. They combined these findings with computer models designed to simulate how and when water was delivered to the Moon millions to billions of years ago.

In the end, the researchers found that Shackleton Crater, a portion of which is located directly at the lunar south pole, is not the most ideal location for water ice, which has long been thought. In contrast, the researchers propose that Haworth Crater is the ideal location for finding water ice. Additionally, the researchers found that some of these regions have been building water ice for as long as 1.5 billion years.

2024 World Computer Chess Championships: The 50th Anniversary

Hosted by the european conference on artificial intelligence.

Sponsored by Google DeepMind.

In August 1970, six chess-playing programs and their developers gathered in New York to compete in the 1st United States Computer Chess Championship. This important event in the history of AI research began a series of annual competitions that continues to this day, longer than any other experiment in computer science history.

OS Orchestration: Stepping Into a Frictionless Future of AI Sparks and Endless Abundance

There’s a very specific reason the tech giants are suddenly racing to get AI running locally on your phone, watch, and smart glasses.

The traditional Operating System (OS) is quietly being retired. Soon, the OS as you know it will be replaced entirely by an omnipresent AI hub.

But if the OS becomes an AI, what happens to that grid of static apps we rely on every day? And when the friction of swiping and searching disappears, how does the underlying economy of the Internet shift?

In my latest piece, I explore what happens next: the death of the app, the rise of dynamic AI “Sparks,” and a hidden token economy where your device doesn’t just cost you money—it generates it.

Want a glimpse at what your digital life looks like when you stop swiping and start orchestrating?


I have been on a breathtaking journey, for decades I have been watching how we connect with the world and each other. If you’ve been around tech long enough, you remember the humble hum of single twisted-pair copper wires, and the sheer, brick-like weight of early cell phones. Fast forward to today, and we are streaming the entirety of human knowledge over millimeter-wave antennas onto super-thin slabs of glass in our pockets.

The Entire Quantum Universe is Inside the Atom

Try InVideo AI for free here: https://invideo.io/i/ArvinAsh This will save you hundreds of dollars that you would otherwise spend on editing, animating and other production costs.

Talk to ME (ARVIN) on Patreon and More:
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REFERENCES
How the 4 fundamental forces work • Why & How do the 4 fundamental forces of n…
History of atom • The Quantum Mechanical model of an atom. W…
Strong Force • Why Don’t Protons Fly Apart in the Nucleus… https://tinyurl.com/2bqv3b9y
Source of mass • How Can MASS and ENERGY be the Same Thing?… https://tinyurl.com/29crnzy2
Medium article https://tinyurl.com/2by2sdbq
Weak Force https://tinyurl.com/25gp9ty7

CHAPTERS
0:00 Why Universe is inside an Atom
1:29 What is an atom?
4:44 Louis de Broglie finds waves!
6:28 Electromagnetic force explained
7:24-Sponsor InVideo
8:35 Strong Force explained, color charges!
12:33 Weak Force explained
14:58 Why is Weak Force called a \.

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