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Archive for the ‘life extension’ category

Sep 14, 2019

Healthy Life Extension / Physical Immortality – The Mass Possibility

Posted by in categories: alien life, life extension

‘Healthy Life Extension / Physical Immortality – the mass possibility ‘is presented as ’a symphony of voices’.

INTRODUCTION

Throughout the ages, pioneers have been questioning the accepted belief systems of the populace, and producing major evolutionary leaps: “The Earth is the centre of the Universe” gave way to the understanding that the earth revolves around the sun. “The Earth is flat” fell away when Columbus did not fall over the edge. The Wright Brothers also flew us into another reality as have countless others. I will be suggesting in the words to follow that the belief system “physical death is inevitable” may have a similar fate.

Sep 14, 2019

Switzerland: Hub of a new ‘Longevity Valley’?

Posted by in category: life extension

Aging Analytics Agency special case study reveals how Switzerland could become the new European Longevity hotspot.

Sep 13, 2019

Morgan Levine at Ending Age-Related Diseases 2019

Posted by in categories: biotech/medical, genetics, life extension

Today, we’re offering another talk from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology.

In her talk, Morgan Levine of the Yale School of Medicine discussed epigenetic biomarkers in detail, discussing the ways in which co-methylation networks provide insight into senescent cells and other facets of biological age.

Sep 13, 2019

Doug Ethell at Ending Age-Related Diseases 2019

Posted by in categories: biotech/medical, life extension, neuroscience

We’re continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology.

Today, we’re releasing a talk from Dr. Doug Ethell, who announced his company’s efforts to combat Alzheimer’s disease, describing where and how this neurodegenerative disease starts and discussing his company’s work on developing therapies for the cribiform plate, which naturally clears amyloid-forming proteins from the brain before they aggregate.

Sep 13, 2019

Prof. Dr. Collin Ewald — ETH Zürich — Extracellular Matrix and Healthy Aging — IdeaXme Show — Ira Pastor

Posted by in categories: aging, biological, biotech/medical, cryonics, DNA, genetics, health, life extension, neuroscience, science

Sep 13, 2019

Dr. Anthony Atala — Wake Forest School of Medicine — Organ Bio-Printing — IdeaXme Show — Ira Pastor

Posted by in categories: 3D printing, aging, bioengineering, bioprinting, biotech/medical, business, health, life extension, science, transhumanism

Sep 12, 2019

Michael West at Ending Age-Related Diseases 2019

Posted by in categories: biotech/medical, life extension

We’re continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology.

In his talk, The Reversal of the Aging of Human Cells: Strategies for Clinical Implementation, Dr. West discussed the differences between germ-line and somatic cells, embryonic regeneration in humans, organisms that do not age, the Weismann Barrier, the ways in which cellular immortality is repressed in human beings (somatic restriction), cellular reprogramming, and how AgeX is attempting to create stem cell populations for regenerative therapies.

Sep 11, 2019

The extreme tech that will help people live forever

Posted by in categories: biotech/medical, life extension

“Everyone is searching for a magic pill that will cure ageing,” explains Richard Siow, who heads up ageing research at King’s College London. “The truth is, lifestyle and diet changes are the most realistic way to extend your life. You can’t just adopt these as you get older. You need to start young – we’re ageing from the moment we’re born.”

Of course, diet and exercise alone won’t enable humans to achieve immortality. We profile the scientists and startups trying to hold back time.

Sep 11, 2019

Toward a unified theory of aging and regeneration

Posted by in categories: biotech/medical, genetics, life extension

Growing evidence supports the antagonistic pleiotropy theory of mammalian aging. Accordingly, changes in gene expression following the pluripotency transition, and subsequent transitions such as the embryonic–fetal transition, while providing tumor suppressive and antiviral survival benefits also result in a loss of regenerative potential leading to age-related fibrosis and degenerative diseases. However, reprogramming somatic cells to pluripotency demonstrates the possibility of restoring telomerase and embryonic regeneration pathways and thus reversing the age-related decline in regenerative capacity. A unified model of aging and loss of regenerative potential is emerging that may ultimately be translated into new therapeutic approaches for establishing induced tissue regeneration and modulation of the embryo-onco phenotype of cancer.

Keywords:

Aging is often defined as a progressive deterioration of an organism over time, wherein the risk of mortality increases exponentially with age in the postreproductive years. Although everyday environmental risks from predation or infectious disease (e.g., stochastic risks) necessarily lead to increased mortality over time, they are not considered core to the definition of the aging process per se [1,2]. Thus, an important criterion of aging is that it encompasses virtually every somatic tissue type, including the gonads (though not necessarily the germ-line cells themselves, given their role in potentially perpetuating the species) [3]. In order to distinguish the aging process from damage that occurs stochastically over time, Benjamin Gompertz described aging as a process leading to an exponential increase in mortality with time, that is, Rm = R0eat where ‘Rm’ represents the probability of mortality between ages ‘t’ and ‘t + 1’.

Sep 11, 2019

Geneticist David Sinclair on the Latest Anti-Aging Studies | Joe Rogan

Posted by in categories: genetics, life extension

Taken from JRE #1349 w/David Sinclair:

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