Lifeboat Foundation

Ah, my sweet summer child. What do you know of inflammation? Inflammation is for the winter, when genes uncoil in your blood and messengers send codes containing the blueprints for proteins to protect you from the harsh diseases of the cold. Inflammation is for those long nights, when the sun hides its face, or rain clouds block the sky, and trillions of little T-cells are born to fight the diseases of cold and flu season.

At least, that’s the news from a new study showing that DNA reacts to the seasons, changing your body’s chemistry depending on the time of year.

The findings, published today in Nature Communications ^1^, show that as many as one-fifth of all genes in blood cells undergo seasonal changes in expression. Genes often are seen as immutable, but a lot of our body’s workings depend upon which genes are translated when. In the winter, the study found, your blood contains a denser blend of immune responders, while summer veins swim with fat-burning, body-building, water-retaining hormones. These seasonal changes could provide insight into inflammatory diseases like hypertension, and autoimmune diseases like type 1 diabetes.

Continue reading “Your DNA Changes With the Seasons, Just Like the Weather” »

When I saw this for the first time, I couldn’t believe my eyes. Well, I still kind of don’t…

Nitinol is a metal alloy of nickel and titanium, where the two elements are present in roughly equal atomic percentages.

Shape memory is the ability of nitinol to undergo deformation at one temperature, then recover its original, undeformed shape upon heating above its “transformation temperature”.

Continue reading “Nitinol – an alloy that remembers its shape” »

The Buck institute is in the spotlight today.

Located in Novato, California, not too far from Mount Burdell Preserve and Olompali State Historic Park, is one of the world’s leading research centres for ageing and age-related diseases—the Buck Institute for Research on Aging.

Opened in 1999 thanks to the substantial bequest of American philanthropist Beryl Hamilton Buck, the Buck Institute set to fulfill her wishes that her patrimony be spent to “extend help towards the problems of the aged, not only the indigent but those whose resources cannot begin to provide adequate care.” Over the years, the Institute has certainly honoured its commitment: The Buck can boast some of the most eminent experts on ageing among its research staff, and a number of laboratories that push forward our understanding of age-related pathologies every day—such as the Campisi Lab and the Kennedy Lab, just to name a few.

The Buck’s approach to investigating ageing is a multifaceted one. The institute rightfully acknowledges the necessity to bring together experts from disparate fields of science—from physics to engineering, from mathematics to anthropology—in order to properly understand the complex networks of biochemical processes underlying ageing and ultimately leading to pathology. Biochemistry, molecular endocrinology, proteomics, genomic stability, and cell biology are only some of the areas of investigation of the Buck, and the medical conditions researched by their teams range from Huntington’s disease to ischemia, to Parkinson’s, to cancer and Alzheimer’s. The three main questions the Buck set to answer are why do ageing tissues lose their regeneration capacity, why do stem cells fail to function with ageing, and how do tissues change during ageing so that they no longer support normal regenerative processes.

Continue reading “The Buck Institute for Research on Aging” »

A very popular theme during NASA’s “Planetary Science Vision 2050 Workshop” was the exploration of Titan. In addition to being the only other body in the Solar System with a nitrogen-rich atmosphere and visible liquid on its surface, it also has an environment rich in organic chemistry. For this reason, a team led by Michael Pauken (from NASA’s Jet Propulsion Laboratory) held a presentation detailing the many ways it can be explored using aerial vehicles.

The presentation, which was titled “Science at a Variety of Scientific Regions at Titan using Aerial Platforms “, was also chaired by members of the aerospace industry – such as AeroVironment and Global Aerospace from Monrovia, California, and Thin Red Line Aerospace from Chilliwack, BC.

Together, they reviewed the various aerial platform concepts that have been proposed for Titan since 2004.

Continue reading “Exploring Titan With Aerial Platforms” »

Rigetti Computing, a leading quantum computing start-up, announced it has raised $64 million in Series A and B funding.

Rigetti Computing is building a cloud quantum computing platform for artificial intelligence and computational chemistry. Rigetti recently opened up private beta testing of Forest, its API for quantum computing in the cloud. Forest emphasizes a quantum-classical hybrid computing model, integrating directly with existing cloud infrastructure and treating the quantum computer as an accelerator.

Continue reading “Quantum computer startup Rigetti Computing Raised $64 Million” »

Yorktown Heights, N.Y. — 06 Mar 2017: IBM (NYSE: IBM) announced today an industry-first initiative to build commercially available universal quantum computing systems. “IBM Q” quantum systems and services will be delivered via the IBM Cloud platform. While technologies that currently run on classical computers, such as Watson, can help find patterns and insights buried in vast amounts of existing data, quantum computers will deliver solutions to important problems where patterns cannot be seen because the data doesn’t exist and the possibilities that you need to explore to get to the answer are too enormous to ever be processed by classical computers.

IBM Quantum Computing Scientists Hanhee Paik (left) and Sarah Sheldon (right) examine the hardware inside an open dilution fridge at the IBM Q Lab at IBM’s T. J. Watson Research Center in Yorktown, NY. On Monday, March 6, IBM announced that it will build commercially available universal quantum computing systems. IBM Q quantum systems and services will be delivered via the IBM Cloud platform and will be designed to tackle problems that are too complex and exponential in nature for classical computing systems to handle. One of the first and most promising applications for quantum computing will be in the area of chemistry and could lead to the discovery of new medicines and materials. IBM aims at constructing commercial IBM Q systems with ~50 qubits in the next few years to demonstrate capabilities beyond today’s classical systems, and plans to collaborate with key industry partners to develop applications that exploit the quantum speedup of the systems. (Connie Zhou for IBM)

Continue reading “Unveils roadmap for commercial ‘IBM Q’ quantum systems” »

Controlling the organization of nanoparticles into patterns in ultrathin polymer films can be accomplished with entropy instead of chemistry, according to a discovery by Dr. Alamgir Karim, UA’s Goodyear Tire and Rubber Company Professor of Polymer Engineering, and his student Dr. Ren Zhang. Polymer thin films are used in a variety of technological applications, for example paints, lubricants, and adhesives. Karim and Zhang have developed an original method—soft-confinement pattern-induced nanoparticle segregation (SCPINS)—to fabricate polymer nanocomposite thin films with well-controlled nanoparticle organization on a submicron scale. This new method uniquely controls the organization of any kind of nanoparticles into patterns in those films, which may be useful for applications involving sensors, nanowire circuitry or diffraction gratings, with proper subsequent processing steps like thermal or UV sintering, that are likely required but the self-organization into directed patterns.

This work, “Entropy-driven segregation of polymer –grafted nanoparticles under confinement,” has been published in the February 2017 issue of Proceedings of the National Academy of Sciences (PNAS).

Intuitively, entropy is associated with disorder of a system. However, for colloidal matter, it has been shown that a system can experience transitions which increase both entropy and visible order. Inspired by this observation, Karim and Zhang investigated the role of entropy in directed organization of polymer-grafted nanoparticles (PGNPs) in polymer thin films. By simply imprinting the blend films into patterned mesa-trench regions, nanoparticles are spontaneously enriched within mesas, forming patterned microdomain structures which coincide with the topographic pattern. This selective segregation of PGNPs is induced by entropic penalty due to the alteration of the grafted chain conformation when confined in ultrathin trench regions.

Continue reading “Researchers develop new method to program nanoparticle organization in polymer thin films” »

Superlubricity nano-structured self-assembling coating repairs surface wear, decreases emissions and increases HP and gas mileage.

Globally about 15 percent of manmade carbon dioxide comes from vehicles. In more developed countries, cars, trucks, airplanes, ships and other vehicles account for a third of emissions related to climate change. Emissions standards are fueling the lubricant additives market with innovation.

Up to 33% of fuel energy in vehicles is used to overcome friction. Tribology is the science of interacting surfaces in relative motion inclusive of friction, wear and lubrication. This is where TriboTEX, a nanotechnology startup is changing the game of friction modification and wear resilience with a lubricant additive that forms a nano-structured coating on metal alloys.

This nano-structured coating increases operating efficiency and component longevity. It is comprised of synthetic magnesium silicon hydroxide nanoparticles that self-assemble as an ultralow friction layer, 1/10 of the original friction resistance. The coating is self-repairing during operation, environmentally inert and extracts carbon from the oil. The carbon diamond-like nano-particle lowers the friction budget of the motor, improving fuel economy and emissions in parallel while increasing the power and longevity of the motor.

Continue reading “Nanotechnology Combatting Global Warming” »

IBM Q is an industry-first initiative to build a commercially available universal quantum computers for business and science. While technologies like AI can find patterns buried in vast amounts of existing data, quantum computers will deliver solutions to important problems where patterns cannot be seen and the number of possibilities that you need to explore to get to the answer are too enormous ever to be processed by classical computers.

IBM Q quantum systems and services will be delivered via the IBM Cloud platform and will be designed to tackle problems that are too complex and exponential in nature for classical computing systems to handle. One of the first and most promising applications for quantum computing will be in the area of chemistry and could lead to the discovery of new medicines and materials. IBM aims at constructing commercial IBM Q systems with ~50 qubits in the next few years to demonstrate capabilities beyond today’s classical systems, and plans to collaborate with key industry partners to develop applications that exploit the quantum speedup of the systems.

Continue reading “IBM launches IBM Q initiative to create 50+ qubit universal quantum computer” »