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Category: chemistry – Page 3

Ultrastructural preservation of a whole large mammal brain with a protocol compatible with human physician-assisted death

Ultrastructural Preservation of a Whole Large Mammal Brain (bioRxiv, 2026) ⚠️ Preprint – not yet peer-reviewed.

A 2026 preprint builds on over a decade of brain preservation research, demonstrating that whole mammalian brains (pigs) can be preserved with remarkable structural fidelity under near–real-world, end-of-life conditions.

The study refines aldehyde-stabilized cryopreservation (ASC)—a technique previously recognized by the Brain Preservation Foundation. This method combines chemical fixation (aldehydes), cryoprotectants, and controlled cooling to prevent ice damage and preserve neural structure at the nanoscale. — What the study shows.

Whole pig brains preserved with intact cellular and synaptic architecture.

Preservation remains viable even with delayed postmortem intervals (~10 minutes)

Tissue remains perfusable and structurally stable after fixation.

Protocol moves toward clinically realistic implementation, not just lab conditions.

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The Sound of Contamination: A Comprehensive Analysis of Endocrine Disruptors and Hazardous Additives in the Headphones

The ToxFree Life for All project analysed 81 headphone models (180 material samples) across Central Europe and online marketplaces like Temu and Shein. 100% of products contained hazardous substances, including bisphenols, phthalates, and flame retardants. While these products do not pose an acute or “imminent” danger, the cumulative and synergistic effects of chronic exposure to these chemical classes pose a long-term risk to public health, therefore having a negative impact on sovereign consumer choice. The individual consumer has limited power to choose a safe product. Consumer protection is a systemic problem that cannot be solved by individual choice; it must be addressed at the institutional level.

Hair-thin fiber-optic sensors could detect cancer by reading multiple biomarkers

Microscopic sensors that are as thin as a strand of hair but capable of taking multiple measurements simultaneously could revolutionize the diagnosis and monitoring of diseases like cancer. Researchers from Adelaide University’s Institute for Photonics and Advanced Sensing and the University of Stuttgart in Germany worked together to develop the tiny sensors using state-of-the-art, ultrafast 3D micro-printing technology.

The unique sensors target specific biomarkers and are printed directly onto the tip of optical fibers. They’re able to monitor several signals at the same time, including temperature and chemical changes. The paper is published in the journal Advanced Optical Materials.

“This breakthrough could lead to next-generation medical tools that track disease, guide treatment and monitor the body in real time,” said Associate Professor Shahraam Afshar, the project’s lead researcher from Adelaide University’s Institute for Photonics and Advanced Sensing.

Atomic disorder strategy could help high-capacity batteries last longer

Researchers at UNIST, in collaboration with the Pohang Accelerator Laboratory (PAL) and KAIST, have introduced a novel approach to stabilizing high-capacity battery materials. By intentionally inducing atomic-level disorder within lithium-rich layered oxide (LRLO) cathodes, the team has effectively minimized structural degradation and energy losses, paving the way for next-generation batteries with higher energy density and longer lifespan.

The findings of this research have been published online in ACS Energy Letters.

Lithium-rich layered oxides (LRLO) are among the most promising cathode materials for future energy storage solutions due to their exceptional capacity, which involves not only metal ions but also oxygen participating in electrochemical reactions. However, their practical application has been hindered by structural instability during repeated charge and discharge cycles, leading to capacity fade and voltage degradation.

Johns Hopkins awarded $15M to develop platform to study neurological diseases, screen chemicals

The DROID platform will extend current in vitro approaches—test tubes and culture dishes—to modeling learning and memory using brain organoids, addressing a critical gap: Current in vitro assays cannot capture higher-order neural responses, and evaluations of neurotoxicity or drug efficacy still primarily rely on animal behavioral tests.

The researchers will also evaluate brain organoids derived from both healthy individuals and patients with Alzheimer’s disease and individuals with SYNGAP1-related disorders—a rare pediatric condition associated with intellectual disability, seizures, and autism—to test neural responses and sensitivity to pharmacological interventions.

By enabling researchers to assess complex neural responses that currently rely on animal behavioral tests, the DROIDp system aims to improve drug discovery and neurotoxicity testing. Ultimately, the goal of this platform is to provide a more predictive, human-relevant approach for studying neurological diseases and evaluating the safety of drugs and chemicals.

Jupiter’s moons may have formed with the ingredients for life

An international team that included Southwest Research Institute has shown how complex organic molecules (COMs), considered essential chemical precursors to life, may have become part of Jupiter’s four largest moons as they formed. The results appear in companion papers published in The Planetary Science Journal and Monthly Notices of the Royal Astronomical Society. Together, the studies shed new light on how the ingredients for life could have reached the Jovian system.

Mussel-inspired glue from recycled plastics can be detached and reused

Researchers at the Department of Energy’s Oak Ridge National Laboratory have invented a reusable adhesive from waste polymers that is tougher than commercial glues, works underwater as well as in dry environments, and bonds a variety of materials, including wood, glass, metal, paper and polymers.

Inspired by the way mussels stick stubbornly to surfaces, the innovative adhesive contains reversible chemical crosslinkers that allow the hardened glue to soften, detach and be reused, unlike current glues, which set permanently after one use.

Today’s projects typically require different glues for different material surfaces—white glue for grade-school art projects, polyvinyl acetates for bookbinding, polyurethanes for shoemaking, silicones for sealing windows and affixing electronic parts, and industrial epoxies for joining aircraft and automobile components.

Impressionist sea slugs create their patterns by arranging colorful photonic crystals

Nudibranchs are often referred to as the butterflies of the sea. Nudibranchs live worldwide, primarily in warm, shallow marine regions, and stand out for their flamboyant colors and diverse shapes. A team from the Max Planck Institute of Colloids and Interfaces in Potsdam and the University of Cambridge has now discovered how they create their colorful patterns. According to their findings, published in the Proceedings of the National Academy of Sciences, the color is produced by nanostructures, each of which creates a specific color impression.

“We were surprised to find that nudibranchs use structural colors,” says Samuel Humphrey, who conducted the research at the Max Planck Institute of Colloids and Interfaces. “Biologists had previously assumed that the colors were produced by pigments.” Pigments are chemical compounds and differently colored pigments have different chemical compositions.

In contrast, in structural colors, color is not a chemical property of the material, but it depends on the length scale of nanostructures composing the material. Such nanostructures, also called photonic crystals, are responsible for the coloration of chameleons, as well as many birds and butterflies. In such structures, color is produced by the regular arrangement of materials with different refractive indices.

Introduction to Quantum Electrodynamics (QED)

It’s now time to dig into quantum field theories with considerably more rigor than earlier in the series. First up is quantum electrodynamics, or QED. This was the first successful QFT, combining quantum mechanics and special relativity. Let’s learn what this model is all about, and how to do math with Feynman diagrams.

Script by andrew mattson, physics phd student at johns hopkins university.

Watch the whole Modern Physics playlist: http://bit.ly/ProfDavePhysics2

Classical Physics Tutorials: http://bit.ly/ProfDavePhysics1
Mathematics Tutorials: http://bit.ly/ProfDaveMaths.
General Chemistry Tutorials: http://bit.ly/ProfDaveGenChem.
Organic Chemistry Tutorials: http://bit.ly/ProfDaveOrgChem.
Biochemistry Tutorials: http://bit.ly/ProfDaveBiochem.
Biology Tutorials: http://bit.ly/ProfDaveBio.

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