Scientists have developed a method to alter the color and brightness of rare earth element luminescence by changing their chemical environment, enabling the design of advanced light-emitting materials. Researchers at HSE University and the Institute of Petrochemical Synthesis of the Russian Acade
The role of fungi in the biogeochemical cycling of gold remains unclear. Here the authors show that fungi can initiate gold oxidation under supergene conditions, thereby impacting gold mobilisation and secondary deposit formation in terrestrial environments.
Researchers at the University of Sydney have successfully performed a quantum simulation of chemical dynamics with real molecules for the first time, marking a significant milestone in the application of quantum computing to chemistry and medicine.
Understanding in real time how atoms interact to form new compounds or interact with light has long been expected as a potential application of quantum technology. Now, quantum chemist Professor Ivan Kassal and Physics Horizon Fellow Dr. Tingrei Tan have shown it is possible using a quantum machine at the University of Sydney.
The innovative work leverages a novel, highly resource-efficient encoding scheme implemented on a trapped-ion quantum computer in the University of Sydney Nanoscience Hub, with implications that could help transform medicine, energy and materials science.
Gene therapy is a technique that rectifies defective or abnormal genes by introducing exogenous genes into target cells to cure the disease. Although gene therapy has gained some accomplishment for the diagnosis and therapy of inherited or acquired cardiovascular diseases, how to efficiently and specifically deliver targeted genes to the lesion sites without being cleared by the blood system remains challenging. Based on nanotechnology development, the non-viral vectors provide a promising strategy for overcoming the difficulties in gene therapy. At present, according to the physicochemical properties, nanotechnology-based non-viral vectors include polymers, liposomes, lipid nanoparticles, and inorganic nanoparticles. Non-viral vectors have an advantage in safety, efficiency, and easy production, possessing potential clinical application value when compared with viral vectors. Therefore, we summarized recent research progress of gene therapy for cardiovascular diseases based on commonly used non-viral vectors, hopefully providing guidance and orientation for future relevant research.
Cardiovascular disease (CVD) leads to almost a third of all deaths worldwide, resulting from atherosclerotic plaque leading to hemadostenosis and blood flow restriction (Park et al., 2020; Tsao et al., 2022). Despite progress in medical technology, CVD is still a major cause of death (Yang et al., 2023). Conventional treatment strategies for CVD include anticoagulation, antiplatelet, thrombolytics, hypolipidemic drugs, and invasive therapies like vascular bypass grafting and stent transplantation (Zhu et al., 2021). However, small molecule drug therapy in conventional treatment strategies is characterized by short half-life and low bioavailability, and long-term use of certain drugs may also lead to side effects such as drug resistance and potential hematological toxicity (Missri, 1979; Fu et al., 2014). Surgical treatment, on the other hand, is more pro-traumatic, requires a longer recovery time, and has a high risk of postoperative complications.
Depending on the type of artificial blood that is made, various raw materials are used. Hemoglobin-based products can use either isolated hemoglobin or synthetically produced hemoglobin.
To produce hemoglobin synthetically, manufacturers use compounds known as amino acids. These are chemicals that plants and animals use to create the proteins that are essential for life. There are 20 naturally occurring amino acids that may be used to produce hemoglobin. All of the amino acid molecules share certain chemical characteristics. They are made up of an amino group, a carboxyl group, and a side chain. The nature of the side chain differentiates the various amino acids. Hemoglobin synthesis also requires a specific type of bacteria and all of the materials needed to incubate it. This includes warm water, molasses, glucose, acetic acid, alcohols, urea, and liquid ammonia.
For other types of hemoglobin-based artificial blood products, the hemoglobin is isolated from human blood. It is typically obtained from donated blood that has expired before it is used. Other sources of hemoglobin come from spent animal blood. This hemoglobin is slightly different from human hemoglobin and must be modified before being used.
Meta released a massive trove of chemistry data Wednesday that it hopes will supercharge scientific research, and is also crucial for the development of more advanced, general-purpose AI systems.
The company used the data set to build a powerful new AI model for scientists that can speed up the time it takes to create new drugs and materials.
The Open Molecules 2025 effort required 6 billion compute hours to create, and is the result of 100 million calculations that simulate the quantum mechanics of atoms and molecules in four key areas chosen for their potential impact on science.
Scientists will finally be able to simulate the chemistry that drives our bodies, our environment, and our technologies.
We know that all the other forces governed by quantum mechanics are transmitted by indivisible particles: photons for the electromagnetic force, which governs light and the basic chemistry of matter; gluons for the strong force, which sticks together protons and neutrons inside atoms; and W and Z bosons for the weak force, which enables certain particles to radioactively decay. If gravity has the same underlying theory as these forces, it should also be carried by its own particle: a graviton. Now researchers, including Claudia Du Rham at Imperial in London, are in the hunt for these mysterious and vanishingly weak particles.
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The small device contains a slurry of chemicals representing primary flavors and mixes them together to mimic the taste of coffee, lemonade, and more.
The phenomenon of biological ultraweak photon emission (UPE), that is, extremely low-intensity emission (10 − 103 photons/cm2/sec) in the spectral range of 200 − 1,000 nm, has been observed in all living systems that have been examined. Here we report experiments that exemplify the ability of novel imaging systems to detect variations in UPE for a set of physiologically important scenarios. We use EMCCD and CCD cameras to capture single visible-wavelength photons with low noise and quantum efficiencies higher than 90%. Our investigation reveals significant contrast between the UPE from live vs. dead mice. In plants we observed that an increase in temperature and injuries both caused an increase in UPE intensity. Moreover, chemical treatments modified the UPE emission characteristics of plants, particularly the application of an anesthetic (benzocaine) to injury, which showed the highest emission among the compounds tested. As a result, UPE imaging provides the possibility of non-invasive label-free imaging of vitality in animals and the responses of plants to stress.
The authors have declared no competing interest.
