Lifeboat Foundation

Cardiovascular Aging & Targeted Senolytic Bio-Therapies — Prof. Dr. Tohru Minamino, MD, PhD, Juntendo University, Japan

Dr. Tohru Minamino is Professor and Chairman of the Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine (https://juntendo-cvbm.com/en/about.html). He also serves as Director of the Cardiovascular Medicine, Juntendo University Hospital. He received his MD from the Chiba University Graduate School of Medicine in 1989 and his PhD from Faculty of Medicine, the University of Tokyo in 1997.

Continue reading “Dr Tohru Minamino, MD, PhD — Cardiovascular Aging & Targeted Senolytic Bio-Therapies — Juntendo Univ” »

“Data science is also absolutely key to our research at the Quadram Institute into the gut microbiome and its influence on human health, all of which is mediated by the complex interactions of micro-organisms, the food we eat, and the environment of the gastro-intestinal tract itself.”

E[datascientist] leverages AI and network science in order to surface scientific connections and explore multi-causal relationships, for example to better understand the microbiome. The platform also improves the digitisation, and reduces the siloisation, of legacy scientific R&D systems, which can be used in tandem with datasets from publicly available databases, all in a standardised format. In this way e[datascientist] supports the entire R&D workflow, accelerating the generation of novel insights and ultimately reducing time to market.

Eagle Genomics plans to continue to be engaged in discussions with a range of other organisations to ensure that its platform continues to become a burgeoning global life sciences knowledge discovery hub.

Amplifying the longevity biotech space with exciting opportunities and brand-new starts. It’s all about connections!

The pace of replacing humans with robots in industries across China has been accelerating rapidly in the past couple of years, with observations on the ground suggesting that most industrial robotics and intelligent-manufacturing integrated service companies had at least doubled their annual sales in 2021.

Pandemic-led manufacturing export boom, concerns over China’s rapidly ageing society and a desire to save money have all contributed to the trend of replacing workers with machines.

Continue reading “Rise of the machines: China’s struggling industries embrace automation” »

The fascinating find shows how little is known about the ocean depths.

The vast colony, believed to be the world’s largest, is home to the remarkable icefish (Neopagetopsis ionah), which has a see-through skull and transparent blood. Icefish are the only vertebrates to have no red blood cells.

I’ve posted some vids of her before. But here she says at 3:52 that she thinks stopping the aging process is farfetched.

Dr. Morgan Levine, a professor who specializes in the biology of aging, answers the internet’s burning questions about aging. Is there anyway to stop aging? Is aging a disease? Do you age slower in space? Dr. Levine answers all these questions and much more!

Continue reading “Age Expert Answers Aging Questions From Twitter | Tech Support” »

What are epinutrients, you ask? Allow us to explain.

In a 2021 study, naturopathic doctor and functional medicine expert Kara Fitzgerald, N.D., author of Younger You, was able to improve participants’ biological age by three years. Sounds like a tall order, but the intervention was actually pretty simple: With a very doable diet and exercise plan, it only took eight weeks to see these results. “A big reason we actually made a difference in eight weeks’ time is because we very intentionally bathed the body in a high amount of epinutrients,” she says on this episode of the mindbodygreen podcast.

Continue reading “5 Epinutrients To Slow Down Aging, From A Naturopathic Doctor” »

Gene editing approaches promise to treat a range of diseases, but delivering editing agents to cells in animal models and humans safely and efficiently has proven challenging. Now, researchers led by a team at the Broad Institute of MIT and Harvard have developed a way to get gene editing proteins inside cells in animal models with high enough efficiency to show therapeutic benefit.

In new work published in Cell, the team shows how they have engineered virus-like particles to deliver base editors — proteins that make programmable single-letter changes in DNA — and CRISPR-Cas9 nuclease, a protein that cuts DNA at targeted sites in the genome. In collaboration with ​​research teams led by Krzysztof Palczewski at the University of California, Irvine, and Kiran Musunuru at the Perelman School of Medicine at the University of Pennsylvania, the team used their particles, called engineered virus-like particles (eVLPs), to disable a gene in mice that can be associated with high cholesterol levels, and partially restored visual function to mice harboring a mutation that causes genetic blindness.

Researchers have developed virus-like particles that deliver therapeutic levels of protein to animal models of disease.

Continue reading “Engineered particles efficiently deliver gene editing proteins to cells in mice” »

In a new study, researchers at Karolinska Institutet have identified the presence of a specific connection between a protein and an lncRNA molecule in liver cancer. By increasing the presence of the lncRNA molecule, the fat depots of the tumor cell decrease, which causes the division of tumor cells to cease, and they eventually die. The study, published in the journal Gut, contributes to increased knowledge that can add to a better diagnosis and future cancer treatments.