Archive for the ‘biotech/medical’ category

Aug 18, 2019

Broccoli in focus when new substance against diabetes has been identified

Posted by in category: biotech/medical

University of Gothenburg NEWS: JUN 15, 2017.

Researchers have identified an antioxidant – richly occurring in broccoli – as a new antidiabetic substance. A patient study shows significantly lower blood sugar levels in participants who ate broccoli extract with high levels of sulforaphane.

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Aug 18, 2019

Stopping Pandemic X: DARPA Names Researchers Working to Halt Outbreaks

Posted by in categories: biotech/medical, health

The Defense Advanced Research Projects Agency (DARPA) launched the Pandemic Prevention Platform (P3) program in 2017, with the eventual goal of halting the spread of any infectious disease outbreak before it can escalate into a pandemic.

Current approaches for recent public health emergencies due to infectious diseases have not produced effective preventive or therapeutic solutions in a relevant timescale. Examples from recent outbreaks such as H3N2 (flu), Ebola, and Zika viruses highlight the significant lag in deployment and efficacy of life-saving solutions.

Aug 18, 2019

From centenarians’ genetic code, a potential new therapy against cardiovascular diseases

Posted by in categories: biotech/medical, genetics, life extension

Some people live much longer than average, partly thanks to their DNA. A study, published in the European Heart Journal, shows that it could be possible to replicate this genetic gift even for those lacking it. The way is now open to an innovative therapy model capable of preventing and fighting cardiovascular diseases through a real rejuvenation of blood vessels.

The study, conducted by the I.R.C.C.S. Neuromed, the I.R.C.C.S. Multimedica and the Department of Medicine, Surgery, and Dentistry, Salerno Medical School University of Salerno, with the support of the Cariplo Foundation and the Italian Ministry of Health, focuses on the gene that encodes the BPIFB4 . In the past, the same research group had identified a variant of this gene, the so-called LAV (“longevity associated variant”), which prevails in people over 100 years of age. Now, through a , researchers have inserted the LAV-BPIFB4 gene into the DNA of animal models particularly susceptible to atherosclerosis and, consequently, to cardiovascular diseases.

“The results—says Annibale Puca, coordinator of a research team at the University of Salerno and at I.R.C.C. MultiMedica—were extremely encouraging. We observed an improvement in the functionality of the endothelium (the inner surface of blood vessels), a reduction of atherosclerotic plaques in the arteries and a decrease in the inflammatory state.”

Aug 18, 2019

The power of electromagnetic energy on breast cancer cells

Posted by in category: biotech/medical

Cancer, by nature, is a destructive force. Sometimes, it spreads, or metastasizes, to a distant body part. While some cancer cells die during this process, others might go on to create additional tumors.

The majority of treatments are ineffective at curing metastatic cancer, so it is vital to find ways to stop the cancer cells from spreading.

Researchers believe electromagnetic fields can help. While this has been a point of interest for years, it is only recently that experts have begun to unravel the mechanism.

Aug 18, 2019

Virtual reality shows potential as drug-free alternative to medication

Posted by in categories: biotech/medical, virtual reality

Reluctant to pop a paracetamol for that headache? Virtual reality might offer an alternative solution.

Aug 17, 2019

Artificial throat could someday help mute people ‘speak’

Posted by in categories: biotech/medical, wearables

Most people take speech for granted, but it’s actually a complex process that involves both motions of the mouth and vibrations of folded tissues, called vocal cords, within the throat. If the vocal cords sustain injuries or other lesions, a person can lose the ability to speak. Now, researchers reporting in ACS Nano have developed a wearable artificial throat that, when attached to the neck like a temporary tattoo, can transform throat movements into sounds.

Scientists have developed detectors that measure movements on human skin, such as pulse or heartbeat. However, the devices typically can’t convert these motions into sounds. Recently, He Tian, Yi Yang, Tian-Ling Ren and colleagues developed a prototype artificial throat with both capabilities, but because the device needed to be taped to the skin, it wasn’t comfortable enough to wear for long periods of time. So the researchers wanted to develop a thinner, skin-like artificial throat that would adhere to the neck like a temporary tattoo.

To make their artificial throat, the researchers laser-scribed graphene on a thin sheet of polyvinyl alcohol film. The flexible device measured 0.6 by 1.2 inches, or about double the size of a person’s thumbnail. The researchers used water to attach the film to the skin over a volunteer’s throat and connected it with electrodes to a small armband that contained a circuit board, microcomputer, power amplifier and decoder. When the volunteer noiselessly imitated the throat motions of speech, the instrument converted these movements into emitted sounds, such as the words “OK” and “No.” The researchers say that, in the future, mute people could be trained to generate signals with their throats that the device would translate into speech.

Aug 17, 2019

Speech Synthesis from neural decoding of spoken sentences

Posted by in categories: biotech/medical, cyborgs, robotics/AI

Technology that translates cortical activity into speech would be transformative for people unable to communicate as a result of neurological impairment. Decoding speech from neural activity is challenging because speaking requires extremely precise and dynamic control of multiple vocal tract articulators on the order of milliseconds. Here, we designed a neural decoder that explicitly leverages the continuous kinematic and sound representations encoded in cortical activity to generate fluent and intelligible speech. A recurrent neural network first decoded direct cortical recordings into vocal tract movement representations, and then transformed those representations to acoustic speech output. Modeling the articulatory dynamics of speech significantly enhanced performance with limited data. Naïve listeners were able to accurately identify and transcribe decoded sentences. Additionally, speech decoding was not only effective for audibly produced speech, but also when participants silently mimed speech. These results advance the development of speech neuroprosthetic technology to restore spoken communication in patients with disabling neurological disorders.

Aug 17, 2019

PALM Ebola Clinical Trial Stopped Early as Regeneron’s REGN-EB3 Therapy Shows Superiority to ZMapp in Preventing Ebola Deaths

Posted by in category: biotech/medical

TARRYTOWN, N.Y., Aug. 12, 2019 /PRNewswire/ — Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that the Company was informed by study investigators that a randomized, controlled trial evaluating four investigational therapies for Ebola virus infection was stopped early because.

Aug 17, 2019

Understanding Cancer using Machine Learning

Posted by in categories: biotech/medical, robotics/AI

Use of Machine Learning (ML) in Medicine is becoming more and more important. One application example can be Cancer Detection and Analysis.


KNIME Fall Summit 2019

Aug 16, 2019

How many genes in the human microbiome?

Posted by in category: biotech/medical

US scientists have begun the daunting task of trying to work out how many genes there are in the human microbiome.

Even when you consider just the gut and the mouth (in itself, a unique research double) the numbers are potentially overwhelming.

Microbiologists and bioinformaticians from Harvard Medical School and Joslin Diabetes Centre gathered all publicly available sequencing data on human oral and gut microbiomes and analyzed the DNA from around 3500 samples – 1400 from mouths and 2100 from guts.

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