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Archive for the ‘biotech/medical’ category

Sep 15, 2017

Why we did not evolve to live forever: Unveiling the mystery of why we age

Posted by in categories: biotech/medical, evolution, genetics, life extension, neuroscience

Researchers at the Institute of Molecular Biology (IMB) in Mainz, Germany, have made a breakthrough in understanding the origin of the ageing process. They have identified that genes belonging to a process called autophagy — one of the cells most critical survival processes — promote health and fitness in young worms but drive the process of ageing later in life. This research published in the journal Genes & Development gives some of the first clear evidence for how the ageing process arises as a quirk of evolution. These findings may also have broader implications for the treatment of neurodegenerative disorders such as Alzheimer’s, Parkinson’s, and Huntington’s disease where autophagy is implicated. The researchers show that by promoting longevity through shutting down autophagy in old worms there is a strong improvement in neuronal and subsequent whole body health.

Getting old, it’s something that happens to everyone and nearly every species on this planet, but the question is, should it? In a recent publication in the journal Genes & Development titled “Neuronal inhibition of the nucleation complex extends lifespan in post-reproductive C. elegans,” the laboratory of Dr Holger Richly at IMB, has found some of the first genetic evidence that may put this question to rest.

As Charles Darwin explained, natural selection results in the fittest individuals for a given environment surviving to breed and pass on their genes to the next generation. The more fruitful a trait is at promoting reproductive success, the stronger the selection for that trait will be. In theory, this should give rise to individuals with traits which prevent ageing as their genes could be passed on nearly continuously. Thus, despite the obvious facts to the contrary, from the point of evolution ageing should never have happened. This evolutionary contradiction has been debated and theorised on since the 1800s. It was only in 1953 with his hypothesis of antagonistic pleiotropy (AP) that George C. Williams gave us a rational explanation for how ageing can arise in a population through evolution. Williams proposed that natural selection enriches genes promoting reproductive success but consequently ignores their negative effects on longevity.

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Sep 15, 2017

The application of nanotechnology to cardiovascular nanomedicine

Posted by in categories: biotech/medical, nanotechnology

Nanostructured systems have the potential to revolutionize both preventive and therapeutic approaches for treating cardiovascular disease. Given the unique physical and chemical properties of nanostructured systems, nanoscience and nanotechnology have recently demonstrated the potential to overcome many of the limitations of cardiovascular medicine through the development of new pharmaceuticals, imaging reagents and modalities, and biomedical devices. A recent review offers an outline of critical issues and emerging developments in cardiac nanotechnology.

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Sep 15, 2017

Study Investigates Vaccine and Oral Medication to Stop Alzheimer’s Years Before it Begins

Posted by in categories: biotech/medical, genetics, neuroscience

Summary: Researchers are testing a new vaccine and oral medication that could delay or prevent Alzheimer’s disease from developing in those with a genetic predisposition.

Source: Keck Medicine USC.

The Keck School of Medicine of USC launches a study exploring whether two different therapies can prevent a leading cause of death.

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Sep 15, 2017

Fat cells converted into stem cells can repair any damaged tissues

Posted by in category: biotech/medical

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Sep 15, 2017

Scientists Grafted Eyes Onto a Blind Organism’s Back, and It Could See

Posted by in categories: biotech/medical, life extension

Scientists at Tufts University were able to graft eyes to the tails of blind Xenopus, giving the tadpoles the ability to detect colors, focus on objects, and consistently follow patterns.

In a breakthrough for regenerative medicine, researchers have developed working eyes attached to the tails of blind Xenopus tadpoles. The tadpoles were able to process visual information from their environment upon the augmentation, helping scientist understand the process of promoting innervation (a part of the body’s nerve supply) in regenerative medicine.

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Sep 15, 2017

We May Finally Have A Way To Stop Scars From Ever Forming

Posted by in category: biotech/medical

Scientists in Australia are developing new compounds that they claimed could stop scars from forming in the first place. The compounds job is to stop an enzyme called lysyl oxidase, which enables the collagen in wound healing to crosslink, resulting in scar formation.

If you sustained an injury, whether it’s large or small, you’ll likely end up with a scar. Scars, after all, are the natural outcome of wound healing, and there’s typically few ways to avoid it. Until now, that is.

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Sep 15, 2017

Immune and Nerve Cells Work Together to Fight Gut Infections

Posted by in categories: biotech/medical, neuroscience

Nerve cells in the gut play a crucial role in the body’s ability to marshal an immune response to infection, according to a new study from Weill Cornell Medicine scientists.

The study, published in Nature, shows that the immune system and nervous system have co-evolved to respond to infectious threats. This means that scientists looking for ways to treat diseases like inflammatory bowel disease or asthma that involve an excessive immune system response may also have to address the nervous system’s role.

“The immune system and neuronal system don’t act independently,” said senior author Dr. David Artis, director of the Jill Roberts Institute for Research in Inflammatory Bowel Disease and the Michael Kors Professor of Immunology at Weill Cornell Medicine. “They are working together.”

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Sep 14, 2017

Researchers Have Linked a Human Brain to the Internet for the First Time Ever

Posted by in categories: biotech/medical, engineering, internet, robotics/AI

Researchers from Wits University have linked a brain directly to the internet. Data gathered from this project could help fuel the next steps in machine learning and brain-computer interfaces.

A team of researchers at Wits University in Johannesburg, South Africa have made a major breakthrough in the field of biomedical engineering. According to a release published on Medical Express, for the first time ever, researchers have devised a way of connecting the human brain to the internet in real time. It’s been dubbed the “Brainternet” project, and it essentially turns the brain “…into an Internet of Things (IoT) node on the World Wide Web.”

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Sep 14, 2017

A DNA nanorobot is programmed to pick up and sort molecules into predefined regions

Posted by in categories: bioengineering, biotech/medical, nanotechnology, robotics/AI

Imagine a robot that could help you tidy your home: roving about, sorting stray socks into the laundry and dirty dishes into the dishwasher. While such a practical helper may still be the stuff of science fiction, Caltech scientists have developed an autonomous molecular machine that can perform similar tasks—at the nanoscale. This “robot,” made of a single strand of DNA, can autonomously “walk” around a surface, pick up certain molecules and drop them off in designated locations.

The work was done in the laboratory of Lulu Qian, assistant professor of bioengineering. It appears in a paper in the September 15 issue of Science.

Why Nanobots?

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Sep 14, 2017

Strathspey Crown LLC : Announces Issuance of US Patent of the First Implantable Intraocular Lens (IOL) with a Video Camera and Wireless Transmission Capability

Posted by in categories: biotech/medical, cyborgs, internet, mobile phones, neuroscience, wearables

NEWPORT BEACH, Calif., July 12, 2017 /PRNewswire/ — Strathspey Crown LLC, a lifestyle healthcare company focused in ophthalmology, medical aesthetic and elective technologies and procedures, today announced that the United States Patent and Trademark Office has issued U.S. Patent No. 9,662,199 covering an implantable intraocular lens with an optic (including accommodating, multifocal and phakic configurations), a camera and an LED display, and a communications module that wirelessly transmit and receive information from an external device (e.g. PDA).

Robert Edward Grant, Founder and Chairman of Strathspey Crown LLC commented, “Video cameras are now a standard feature of smart phone technology and wearable cameras have become popularized by companies like Google and Snap in recent years. This patent represents a significant step forward in the rapidly growing sector of human cyborg technology. The eye, as a transparent medium for light, is ideal for advanced and rechargeable implantables that enable video capture of all of life’s experiences. Our broader vision is to develop ground-breaking medical-grade ocular smart implantables that integrate cellular, WIFI and 802.11 transmissions in an elegant cognitive interface that we believe will enhance human intelligence, augment perceived reality, and digitally capture experiences and individual memories. We look forward to several continuations and expansions on this important intellectual property portfolio.”

Grant further commented, “Although Samsung, Sony and Google have all recently filed patent applications related to the same field, Strathspey Crown is thus far the only company to hold an issued patent in this promising ocular smart implant category. Our first camera-integrated acrylic IOLs will be completed in 2018, upon which we plan to pursue an FDA Investigational Device Exemption (IDE) and subsequent Pre-Market Approval (PMA) and related clinical trial.”

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