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Why the Next 10 Years May Add 50 to Your Lifespan | Dr. Derya Unutmaz

The next 10 years may add decades to human lifespan by compressing the time it takes to understand, treat, and prevent disease. In this episode, Dr. Derya Unutmaz explains why accelerating AI could transform drug discovery, shorten clinical trials, and push cancer treatment toward increasingly personalized interventions. He also reframes AI not as an existential threat, but as a medical enabler that doctors may soon be ethically obligated to use.

Get weekly, protocol-driven research breakdowns from Dr. Rhonda Patrick to advance healthspan, longevity, brain health, and resilience: https://www.foundmyfitness.com/newsle… 00:00:00 Introduction 00:02:16 Why the next 10 years may add 50 to your lifespan 00:06:25 How AI is transforming drug discovery 00:11:55 Could digital twins shorten clinical trials? 00:14:31 Can AI predict drug safety and efficacy? 00:18:46 Have we already reached AGI? 00:24:28 Why AI may be medicine’s greatest force multiplier 00:30:41 Can AI replicate a scientist’s biological intuition? 00:37:22 Is it malpractice for doctors not to use AI? 00:43:24 What happens when AI monitors disease in real time? 00:46:58 Which AI models should doctors trust? 00:52:34 Claude vs. GPT—does the model matter for diagnosis? 00:56:04 Generalist vs. specialized AI—which works better in medicine? 00:59:30 Why cancer is so hard to cure 01:03:24 Could cancer be curable within a decade? 01:07:35 Can AI design cancer treatments on demand? 01:09:37 How AI could curb overtreatment and side effects 01:12:33 Predicting cancer years before it forms—is it possible? 01:18:55 Why biology could go exponential with AI 01:24:04 Why aging may be easier to prevent than reverse 01:29:56 Can the body be engineered to resist aging? 01:35:13 Can AI model how gene therapy will behave? 01:39:17 What people who reach 110+ reveal about Human 2.0 01:41:27 From Dolly to Yamanaka factors—the case for cellular age reversal 01:46:02 Why full-body rejuvenation is an engineering problem 01:53:49 What happens when AI reasons longer about biology? 01:56:31 The biosecurity dilemma of powerful AI 02:01:17 What should we actually measure to track aging? 02:07:40 How old immune cells distort aging clocks 02:10:28 Why reversing brain aging is uniquely difficult 02:16:55 The ultimate prompt for extending lifespan 02:18:56 What data does a true digital twin need? 02:23:38 How to build a mini digital twin today 02:28:32 How to give AI a long-term memory of your data 02:31:39 Why personal baselines matter for AI advice Derya Unutmaz, M.D. X: https://twitter.com/DeryaTR_ EPISODE LINKS Show notes & transcript: https://www.foundmyfitness.com/episod… PODCAST INFO Apple Podcasts: https://podcasts.apple.com/us/podcast… Spotify: https://open.spotify.com/episode/4BPh… SUPPORT MY MISSION Access more than 130 episodes of my premium podcast (The Aliquot) when you become a FoundMyFitness Premium Member: https://www.foundmyfitness.com/crowds… #ai.

CHAPTERS:
00:00:00 Introduction.
00:02:16 Why the next 10 years may add 50 to your lifespan.
00:06:25 How AI is transforming drug discovery.
00:11:55 Could digital twins shorten clinical trials?
00:14:31 Can AI predict drug safety and efficacy?
00:18:46 Have we already reached AGI?
00:24:28 Why AI may be medicine’s greatest force multiplier.
00:30:41 Can AI replicate a scientist’s biological intuition?
00:37:22 Is it malpractice for doctors not to use AI?
00:43:24 What happens when AI monitors disease in real time?
00:46:58 Which AI models should doctors trust?
00:52:34 Claude vs. GPT—does the model matter for diagnosis?
00:56:04 Generalist vs. specialized AI—which works better in medicine?
00:59:30 Why cancer is so hard to cure.
01:03:24 Could cancer be curable within a decade?
01:07:35 Can AI design cancer treatments on demand?
01:09:37 How AI could curb overtreatment and side effects.
01:12:33 Predicting cancer years before it forms—is it possible?
01:18:55 Why biology could go exponential with AI
01:24:04 Why aging may be easier to prevent than reverse.
01:29:56 Can the body be engineered to resist aging?
01:35:13 Can AI model how gene therapy will behave?
01:39:17 What people who reach 110+ reveal about Human 2.0
01:41:27 From Dolly to Yamanaka factors—the case for cellular age reversal.
01:46:02 Why full-body rejuvenation is an engineering problem.
01:53:49 What happens when AI reasons longer about biology?
01:56:31 The biosecurity dilemma of powerful AI
02:01:17 What should we actually measure to track aging?
02:07:40 How old immune cells distort aging clocks.
02:10:28 Why reversing brain aging is uniquely difficult.
02:16:55 The ultimate prompt for extending lifespan.
02:18:56 What data does a true digital twin need?
02:23:38 How to build a mini digital twin today.
02:28:32 How to give AI a long-term memory of your data.
02:31:39 Why personal baselines matter for AI advice.

Derya Unutmaz, M.D.
X: https://twitter.com/DeryaTR_

EPISODE LINKS
Show notes & transcript: https://www.foundmyfitness.com/episod…

Updates on nature, land and biodiversity

Nature is humanity’s lifeline. Human health, food, economies and well-being depend on nature. Yet nature is in crisis. One million of the world’s estimated 8 million species of plants and animals are threatened with extinction. Meanwhile, ecosystem degradation is affecting the well-being of 40 per cent of the global population.

The spotlight on nature and biodiversity highlights updates from around the UN System, from partners and others, helping to call attention to the need for a just, prosperous and sustainable future for all.

George Dvorsky: Specialization is for Insects

Fourteen years ago, I sat down with George Dvorsky for almost 1 hour and 40 minutes. We argued about everything: transhumanism and the paleo diet, animal uplift and non-human person rights, mass extinction, SETI, and whether alien intelligence would be friendly or hostile.

One quote from that conversation has stayed with me ever since. Robert A. Heinlein:

“A human being should be able to change a diaper, plan an invasion, butcher a hog, conn a ship, design a building, write a sonnet, balance accounts, build a wall, set a bone, comfort the dying, take orders, give orders, cooperate, act alone, solve equations, analyze a new problem, pitch manure, program a computer, cook a tasty meal, fight efficiently, die gallantly. Specialization is for insects.”

In 2012, that sounded like a provocation. In 2026, in the age of AI, it sounds like a survival strategy. When machines out-specialize us at everything, what is left for humans? Perhaps precisely this: to be generalists. To be whole.

Was George right then? Is Heinlein right now?

Watch the full interview and judge for yourself: [ https://snglrty.co/4pU2ZtQ](https://snglrty.co/4pU2ZtQ)

Continue reading “George Dvorsky: Specialization is for Insects” | >

Researchers identify class of ‘oddball’ meteorite that killed the dinosaurs

A rare CO chondrite meteorite was the probable impacter that struck Earth 66 million years ago, wiping out 75% of Earth’s species, including nonavian dinosaurs. These findings are published in Science Advances. Researchers at the University of British Columbia (UBC), Paris, Brussels and Vienna, used advanced nickel isotope analysis of samples to narrow down the composition of the deadly Cretaceous-Paleogene meteorite.

“Carbonaceous chondrites of the Ornans class are definitely not like the typical meteors you find in museum collections,” says Dr. Philippe Claeys, who worked on the study as a visiting professor at UBC.

“A CO contains much less volatile elements—like carbon, zinc, water and particularly sulfur—than other classes of meteorites we’ve discovered so far on Earth. It doesn’t alter our theory of what caused the extinction event—but it makes it less likely that sulfur contained in the impacter was the smoking gun. The fine debris thrown into the atmosphere would have been the primary factor.”

Alien world chemistry found inside meteorite that struck New Jersey home

On July 16, 2024, a daytime meteor shook New York City with a sonic boom as it passed just south of the Statue of Liberty. Now, an international team of researchers reports in the journal Science Advances that a short time later, a meteorite weighing more than 2 pounds crashed through the roof of a house in the town of Hillsborough, New Jersey.

“A forensic study of the fragments revealed that they contained preserved bits from near the surface of a primitive asteroid, where it experienced concentrated salty fluids—a process not previously known from this type of protoplanet world,” said lead author and meteor astronomer Peter Jenniskens of the SETI Institute and NASA’s Ames Research Center in California’s Silicon Valley.

On that day, a rock the size of a heavy airline bag entered Earth’s atmosphere at a speed of 32,000 miles/h (14.4 kilometers per second). Sixty observers from New York, New Jersey, Connecticut, Rhode Island and Pennsylvania reported seeing the meteor to the American Meteor Society, while 16 in New York and New Jersey felt the shock wave.

Asteroid breakup may explain inner solar system bombardment 800 million years ago

A Southwest Research Institute-led study has proposed a connection between a specific collision in the main asteroid belt and an inner-solar-system-wide bombardment episode that may have had measurable biological and geological consequences on Earth. The research suggests that the catastrophic breakup of the Eulalia parent body could be linked to an impact shower that struck the terrestrial planets about 800 million years ago. The work is published on the arXiv preprint server.

“The role impacts have played in shaping the origin and evolution of life in our solar system is poorly understood,” said Dr. William Bottke, an executive director in SwRI’s Solar System Science and Exploration Division in Boulder, Colorado. He also directs the Center for Lunar Origin and Evolution (CLOE), SwRI’s team in NASA’s Solar System Exploration Research Virtual Institute, and is lead author of a paper describing this research. “The heavily cratered surface of the moon serves as a reminder of the large impacts in Earth’s past, but so far, only the Chicxulub impact event 66 million years ago has been strongly linked to a specific effect on life, namely the mass extinction of the dinosaurs.”

Finding geological evidence of impacts older than 650 million years ago on Earth is challenging because of the constant renewal of our home planet’s surface. Earth’s landscape constantly changes as constructive forces such as volcanoes and plate tectonics build it up, while destructive forces such as weathering wear it down. One way researchers have searched for clues about Earth’s past is to study asteroid shower events.

Can We Re-grow You?

For all of medical history, we’ve tried to persuade sick cells to behave better. What if instead we just swapped them out? Can we insert new brain cells grown from your own skin cells? And what does any of this have to do with sending one’s own cells into space, or rescuing animals on the very brink of extinction? Today Eagleman talks with stem cell biologist Jeanne Loring about the exciting next horizons.

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