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Category: neuroscience

Many grooves and dimples on the surface of the brain are unique to humans, but they’re often dismissed as an uninteresting consequence of packing an unusually large brain into a too-small skull.

But neuroscientists are finding that these folds are not mere artifacts, like the puffy folds you get when forcing a sleeping bag into a stuff sack. The depths of some of the smallest of these grooves seem to be linked to increased interconnectedness in the brain and better ability.

In a study published in The Journal of Neuroscience, University of California, Berkeley researchers show that in children and adolescents, the depths of some small grooves are correlated with increased connectivity between regions of the brain—the lateral and lateral parietal cortex—involved in reasoning and other high-level cognitive functions.

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Sitting might be a comfortable and convenient way to spend much of your day, but a new study of older adults suggests it can lead to brain shrinkage and cognitive issues, irrespective of how much exercise you’re managing to fit in.

The research counters the idea that periods of sitting can be balanced out by periods of being active, at least when it comes to brain health in people aged 50 or above.

The study researchers, from Vanderbilt University, the University of Pittsburgh, and Seoul National University, think that too much sitting or lying down (known as sedentary behavior) can impact the brain and increase the risk of different types of dementia later in life, including Alzheimer’s disease.

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Researchers found that interoceptive awareness—the ability to sense internal bodily states—predicts whether people’s moral judgments match group norms. Brain scans revealed that resting-state activity in specific brain regions mediates this relationship.

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Scientists say they’ve put together a new kind of molecular toolkit that could eventually be used to treat a variety of brain diseases, possibly including epilepsy, sleep disorders and Huntington’s disease.

The kit currently contains more than 1,000 tools of a type known as enhancer AAV vectors, with AAV standing for “adeno-associated virus.” A consortium that included researchers from Seattle’s Allen Institute for Brain Science and the University of Washington combined harmless adeno-associated viruses with snippets of engineered DNA to create a gene-therapy package that could target specific neurons in the brain while having no effect on other cells.

Researchers laid out their findings in a set of eight studies published today in the Cell Press family of journals. The work is part of a project called the Armamentarium for Precision Brain Cell Access, funded through the National Institutes of Health’s BRAIN Initiative.

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Ultra-processed foods now dominate the food supplies of high-income countries, with over 50% of energy intake coming from ultra-processed foods in the United States. Observational data has revealed that greater ultra-processed food consumption is associated with adverse mental health outcomes, while data from randomized controlled trials has demonstrated improvements to mental health following reduction in ultra-processed food intake. Ultra-processed foods are known to contain high concentrations of microplastics, largely due to both the processing and packing procedures. In light of recent findings which demonstrated alarming microplastic concentrations in the human brain, we propose that microplastics may partially mediate the adverse mental health effects of increasing ultra-processed food intake. In this viewpoint, we discuss the overlapping mechanisms for adverse mental health, paucity of research in the area, and propose a Dietary Microplastic Index (DMI) to study this potential relationship.

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Watch the full interviews with Dr. Christof Koch and Professor Michael Levin, which are discussed in this video, here:
• Bioelectric Fields: A Paradigm Shift In Bi…
• Famous Neuroscientist on 5-MeO-DMT and Int…

Hans Busstra talks to Dr. Bernardo Kastrup about the groundbreaking work of Professor Michael Levin and Dr. Christof Koch.

Levin’s research into bio-electric fields reveals that cellular networks use electrical signals not just for immediate physiological tasks, but to coordinate complex patterning and memory across tissues—suggesting a kind of distributed intelligence in living systems.

Christof Koch, meanwhile, champions Integrated Information Theory (IIT), which proposes that consciousness is an intrinsic property of certain physical systems with high levels of causal interconnectivity.

Both lines of inquiry challenge the traditional reductionist view that mind is merely an emergent byproduct of neural activity. Instead, they point to a more holistic, perhaps even fundamental, role for information and consciousness in nature. Though Levin and Koch make no explicit metaphysical claims in their work, their empirical findings and views are very much in line with analytic idealism.

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Higher intakes of black tea, berries, citrus fruits and apples could help to promote healthy ageing, new research has found.

This study conducted by researchers from Edith Cowan University, Queen’s University Belfast and Harvard T.H. Chan School of Public Health, found that foods rich in flavonoids could help to lower the risk of key components of unhealthy ageing, including frailty, impaired physical function and poor mental health.

“The goal of medical research is not just to help people live longer but to ensure they stay healthy for as long as possible,” ECU Adjunct Lecturer Dr Nicola Bondonno said.

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