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Study reveals unexpected link between dopamine and serotonin in the brain

Researchers at Karolinska Institutet, Columbia University and the University of San Francisco, have uncovered a previously unknown mechanism by which dopamine, a key brain chemical vital for movement and motivation, can affect brain activity indirectly by boosting serotonin. The study was published in Science Advances.

Dopamine is a key chemical messenger that supports many essential brain functions, including motivation, movement, and learning. Although dopamine acts throughout the brain, it plays an especially central role in the basal ganglia, a network of interconnected regions responsible for selecting which behaviors we express.

The basal ganglia and dopamine are deeply involved in neuropsychiatric and neurodegenerative diseases, and many widely used medications target this network.

Collaborating minds think alike, processing information in similar ways in a shared task, study shows

Whether great minds think alike is up for debate, but the collaborating minds of two people working on a shared task process information alike, according to a study published in PLOS Biology by Denise Moerel and colleagues from Western Sydney University in Australia.

Humans rely on collaboration for everything from raising food to raising children. But to cooperate successfully, people need to make sure that they are seeing the same things and working within the same rules. We must agree that the red fruits are the ones that are ripe and that we will leave green fruits alone.

Behavioral collaboration requires that people think in the same way and follow the same instructions. To better understand people’s cognitive processes during a shared task, the authors of this study collected data from 24 pairs of people.

Hidden Thyroid Problem in Pregnancy Linked to Autism

Researchers found that mothers with untreated or persistent thyroid hormone imbalance across pregnancy face a higher chance of having children diagnosed with autism.

The study also revealed that longer periods of imbalance led to higher autism rates in offspring. The results emphasize the importance of frequent thyroid monitoring.

Thyroid imbalance in pregnancy linked to higher autism risk.

Nanoflowers rejuvenate old and damaged human cells by replacing their mitochondria

Biomedical researchers at Texas A&M University may have discovered a way to stop or even reverse the decline of cellular energy production—a finding that could have revolutionary effects across medicine.

Dr. Akhilesh K. Gaharwar and Ph.D. student John Soukar, along with their fellow researchers from the Department of Biomedical Engineering, have developed a new method to give damaged cells new mitochondria, returning energy output to its previous levels and dramatically increasing cell health.

Mitochondrial decline is linked to aging, heart disease and neurodegenerative disorders. Enhancing the body’s natural ability to replace worn-out mitochondria could fight all of them.

Collaborative rule learning promotes interbrain information alignment

How do brains align during social interaction to support shared understanding? This study shows that interbrain information alignment emerges rapidly and strengthens with practice, with distinct neural processes supporting sensory synchrony during early alignment and shared cognitive representation in real pairs during late alignment.

Parkinson’s Link to Gut Bacteria Suggests Unexpectedly Simple Treatment

Researchers have suspected for some time that the link between our gut and brain plays a role in the onset of Parkinson’s disease.

A recent study identified gut microbes likely to be involved and linked them with decreased riboflavin (vitamin B2) and biotin (vitamin B7), suggesting an unexpectedly simple treatment that may help: B vitamins.

“Supplementation therapy targeting riboflavin and biotin holds promise as a potential therapeutic avenue for alleviating Parkinson’s symptoms and slowing disease progression,” said medical researcher Hiroshi Nishiwaki from Nagoya University in Japan, when the paper was published in May 2024.

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