Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: neuroscience – Page 2

Karl J. Friston

Professors Karl Friston & Mark Solms, pioneers in the fields of neuroscience, psychology, and theoretical biology, delve into the frontiers of consciousness: “Can We Engineer Artificial Consciousness?”. From mimicry to qualia, this historic conversation tackles whether artificial consciousness is achievable — and how. Essential viewing/listening for anyone interested in the mind, AI ethics, and the future of sentience. Subscribe to the channel for more profound discussions!

Professor Karl Friston is one of the most highly cited living neuroscientists in history. He is Professor of Neuroscience at University College London and holds Honorary Doctorates from the University of Zurich, University of York and Radboud University. He is the world expert on brain imaging, neuroscience, and theoretical neurobiology, and pioneers the Free-Energy Principle for action and perception, with well-over 300,000 citations. Friston was elected a Fellow of the Academy of Medical Sciences (1999). In 2000 he was President of the international Organization of Human Brain Mapping. He was elected a Fellow of the Royal Society in 2006. He became a Fellow of the Royal Society of Biology in 2012 and was elected as a member of EMBO (excellence in the life sciences) in 2014 and the Academia Europaea in (2015).

Professor Mark Solms is director of Neuropsychology in the Neuroscience Institute of the University of Cape Town and Groote Schuur Hospital (Departments of Psychology and Neurology), an Honorary Lecturer in Neurosurgery at the Royal London Hospital School of Medicine, an Honorary Fellow of the American College of Psychiatrists, and the President of the South African Psychoanalytical Association. He is also Research Chair of the International Psychoanalytical Association (since 2013). He founded the International Neuropsychoanalysis Society in 2000 and he was a Founding Editor (with Ed Nersessian) of the journal Neuropsychoanalysis. He is Director of the Arnold Pfeffer Center for Neuropsychoanalysis at the New York Psychoanalytic Institute. He is also Director of the Neuropsychoanalysis Foundation in New York, a Trustee of the Neuropsychoanalysis Fund in London, and Director of the Neuropsychoanalysis Trust in Cape Town.

TIMESTAMPS:
0:00 — Introduction.
0:45 — Defining Consciousness & Intelligence.
8:20 — Minimizing Free Energy + Maximizing Affective States.
9:07 — Knowing if Something is Conscious.
13:40 — Mimicry & Zombies.
17:13 — Homology in Consciousness Inference.
21:27 — Functional Criteria for Consciousness.
25:10 — Structure vs Function Debate.
29:35 — Mortal Computation & Substrate.
35:33 — Biological Naturalism vs Functionalism.
42:42 — Functional Architectures & Independence.
48:34 — Is Artificial Consciousness Possible?
55:12 — Reportability as Empirical Criterion.
57:28 — Feeling as Empirical Consciousness.
59:40 — Mechanistic Basis of Feeling.
1:06:24 — Constraints that Shape Us.
1:12:24 — Actively Building Artificial Consciousness (Mark’s current project)
1:24:51 — Hedonic Place Preference Test & Ethics.
1:30:51 — Conclusion.

EPISODE LINKS:
- Karl’s Round 1: https://youtu.be/Kb5X8xOWgpc.
- Karl’s Round 2: https://youtu.be/mqzyKs2Qvug.
- Karl’s Lecture 1: https://youtu.be/Gp9Sqvx4H7w.
- Karl’s Lecture 2: https://youtu.be/Sfjw41TBnRM
- Karl’s Lecture 3: https://youtu.be/dM3YINvDZsY
- Mark’s Round 1: https://youtu.be/qqM76ZHIR-o.
- Mark’s Round 2: https://youtu.be/rkbeaxjAZm4

CONNECT:

Continue reading “Karl J. Friston” | >

Like radar, a brain wave sweeps a cortical region to read out information held in working memory

Imagine you are a security guard in one of those casino heist movies where your ability to recognize an emerging crime will depend on whether you notice a subtle change on one of the many security monitors arrayed on your desk. That’s a challenge of visual working memory.

According to a new study by neuroscientists in The Picower Institute for Learning and Memory at MIT, the ability to quickly spot the anomaly could depend on a theta-frequency brain wave (3–6 Hz) that scans through a region of the cortex that maps your field of view.

The findings in animals, published in Neuron, help to explain how the brain implements visual working memory and why performance is both limited and variable.

Key nervous system components shown to influence gastrointestinal tumor growth

Australian researchers have identified two nervous system components that drive tumor growth in gastrointestinal cancers, creating promising new avenues for treatment with existing approved therapies.

Our gut contains its very own nervous system and is commonly regarded as the second brain. Key players of this system are neuropeptides, the signaling factors that are produced and released by nerves. These factors relay messages throughout our nervous system by connecting to receptors on the outside of cells, influencing a variety of processes.

The team at the Olivia Newton-John Cancer Research Institute (ONJCRI) and La Trobe School of Cancer Medicine discovered that CGRP, a common neuropeptide, and its receptor RAMP1 influence tumor growth in colorectal and stomach cancers.

Gluten sensitivity linked to gut–brain interaction, not gluten itself, study finds

A study has revealed that gluten sensitivity, which affects approximately 10% of the global population, is not actually about gluten but part of the way the gut and brain interact.

The findings are expected to set a new benchmark for how gluten sensitivity is defined, diagnosed and treated.

The research review, published today in The Lancet, examined current published evidence for non-celiac gluten sensitivity (NCGS) to better understand this highly prevalent condition.

Family and peer conflicts predict teenage mental health issues, study finds

Identifying the factors that contribute to psychopathology and increase the risk of experiencing specific mental health conditions is a long-standing goal for many psychology researchers. While past studies have highlighted the crucial role of some experiences, particularly challenging events unfolding during childhood and adolescence, in the development of mental health disorders, their influence is often difficult to quantify and differentiate from other factors that could contribute to psychopathology.

Recent technological advances, particularly the development of increasingly sophisticated and computational analysis tools, have opened new possibilities for the study of disorders and their underlying patterns. When used to analyze the large amounts of data collected by and professionals over the past decades, these methods could help to uncover correlations between specific variables and hidden trends that are associated with psychopathology.

Researchers at Washington University in St. Louis and Washington University School of Medicine recently set out to explore the possible contribution of different factors to poor mental health among teenagers using data mining techniques (i.e., computational approaches to uncover patterns in data). Their findings, published in Nature Mental Health, suggest that , particularly conflicts between , bullying or a loss of reputation among peers, are the strongest predictors of psychopathology in adolescents.

Rare blue proteins from cold-adapted microbes could serve as prototypes for molecular on-off switches

Imagine the magnificent glaciers of Greenland, the eternal snow of the Tibetan high mountains, and the permanently ice-cold groundwater in Finland. As cold and beautiful as these are, for the structural biologist Kirill Kovalev, they are more importantly home to unusual molecules that could control brain cells’ activity.

Kovalev, EIPOD Postdoctoral Fellow at EMBL Hamburg’s Schneider Group and EMBL-EBI’s Bateman Group, is a physicist passionate about solving biological problems. He is particularly hooked by rhodopsins, a group of colorful proteins that enable aquatic microorganisms to harness sunlight for energy.

“In my work, I search for unusual rhodopsins and try to understand what they do,” said Kovalev. “Such molecules could have undiscovered functions that we could benefit from.”

Chronic traumatic encephalopathy rare among individuals with isolated brain injuries

Chronic traumatic encephalopathy (CTE) is more common in people who experience extensive repetitive head impacts, and infrequent among individuals with isolated brain injuries or less extensive impacts, researchers from the Brain Injury Research Center of Mount Sinai have found.

The study, published in the Journal of Neuropathology & Experimental Neurology, adds to knowledge of CTE, which has received extensive media attention amidst limited research in representative samples.

CTE is characterized by a neurodegenerative pathology involving abnormal accumulations of tau protein in the brain associated with head trauma, primarily identified in deceased people who sustained extensive exposure to repetitive head impacts while playing contact sports—especially American-style football. CTE has been reported more rarely in individuals who sustained repetitive head impacts through head-banging, military service, or intimate partner violence.

/* */