Allogeneic cell therapeutics are currently being developed to overcome manufacturing bottlenecks of autologous products but face allorejection as their biggest obstacle. This review analyzes the immunogenicity of allogeneic cell therapeutics, outlines engineering strategies for immune evasion, and summarizes recent milestone achievements.
Fast-charging lithium-ion batteries are ubiquitous, powering everything from cellphones and laptops to electric vehicles. They’re also notorious for overheating or catching fire.
Now, with an innovative computational model, a University of Wisconsin–Madison mechanical engineer has gained new understanding of a phenomenon that causes lithium-ion batteries to fail.
Developed by Weiyu Li, an assistant professor of mechanical engineering at UW–Madison, the model explains lithium plating, in which fast charging triggers metallic lithium to build up on the surface of a battery’s anode, causing the battery to degrade faster or catch fire.
A chemical reaction that’s vital to a range of commercial and industrial goods may soon be initiated more effectively and less expensively thanks to a collaboration that included Oregon State University College of Engineering researchers.
The study, published in Nature, involves hydrogenation —adding the diatomic hydrogen molecule, H2, to other compounds.
“Hydrogenation is a critical and diverse reaction used to create food products, fuels, commodity chemicals and pharmaceuticals,” said Zhenxing Feng, associate professor of chemical engineering. “However, for the reaction to be economically viable, a catalyst such as palladium or platinum is invariably required to increase its reaction rate and thus lower cost.”
A modified manufacturing process for electric vehicle batteries, developed by University of Michigan engineers, could enable high ranges and fast charging in cold weather, solving problems that are turning potential EV buyers away.
“We envision this approach as something that EV battery manufacturers could adopt without major changes to existing factories,” said Neil Dasgupta, U-M associate professor of mechanical engineering and materials science and engineering, and corresponding author of the study published in Joule.
“For the first time, we’ve shown a pathway to simultaneously achieve extreme fast charging at low temperatures, without sacrificing the energy density of the lithium-ion battery.”
A team of researchers led by a physics graduate student at the University of Massachusetts Amherst made the surprising discovery of what they call a “shape-recovering liquid,” which defies some long-held expectations derived from the laws of thermodynamics.
The research, published in Nature Physics, details a mixture of oil, water and magnetized particles that, when shaken, always quickly separates into what looks like the classically curvaceous lines of a Grecian urn.
“Imagine your favorite Italian salad dressing,” says Thomas Russell, Silvio O. Conte Distinguished Professor of Polymer Science and Engineering at UMass Amherst and one of the paper’s senior authors.
Knitted microtissues, seeded with stem cells and other precursor cells, may soon accelerate the healing process of different soft tissues in humans. The work is led by researchers at the Defense Fabric Discovery Center at MIT Lincoln Laboratory as well as the MIT Department of Mechanical Engineering.
The process of catalysis—in which a material speeds up a chemical reaction—is crucial to the production of many of the chemicals used in our everyday lives. But even though these catalytic processes are widespread, researchers often lack a clear understanding of exactly how they work.
A new analysis by researchers at MIT has shown that an important industrial synthesis process, the production of vinyl acetate, requires a catalyst to take two different forms, which cycle back and forth from one to the other as the chemical process unfolds.
Previously, it had been thought that only one of the two forms was needed. The new findings are published today in the journal Science, in a paper by MIT graduate students Deiaa Harraz and Kunal Lodaya, Bryan Tang, Ph.D., and MIT professor of chemistry and chemical engineering Yogesh Surendranath.
Treatment with chimeric antigen receptor (CAR)-T cell therapies is associated with important immune-related adverse events. In this Review, the authors discuss the standard-of-care management for cytokine release and immune effector cell-associated neurotoxicity syndromes, and the potential of other T cell druggable targets as well as cellular engineering strategies to develop safer CAR-T cells.
Could we reach Alpha Centauri in just 60 years? The Nuclear Salt Water Rocket (NSWR) might be the answer! With speeds of up to 7.6% of light speed, this game-changing propulsion system could make interstellar travel a reality within a single human lifetime. But how does it work? What challenges stand in the way? In this episode, we break down everything you need to know about NSWR and its potential to revolutionize space travel!
Watch now and explore the future of interstellar exploration!
Paper link : https://path-2.narod.ru/design/base_e… 00:00 Introduction 00:58 How the NSWR Works and Its Breakthrough Potential 03:41 Feasibility and Engineering Challenges 06:30 The Potential Impact on Space Exploration 09:35 Outro 09:44 Enjoy MUSIC TITLE : Starlight Harmonies MUSIC LINK : https://pixabay.com/music/pulses-star… Visit our website for up-to-the-minute updates: www.nasaspacenews.com Follow us Facebook: / nasaspacenews Twitter:
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00:58 How the NSWR Works and Its Breakthrough Potential.
03:41 Feasibility and Engineering Challenges.
06:30 The Potential Impact on Space Exploration.
09:35 Outro.
09:44 Enjoy.
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A team of researchers from University of Toronto Engineering has discovered hidden multi-dimensional side channels in existing quantum communication protocols.
The new side channels arise in quantum sources, which are the devices that generate the quantum particles —typically photons—used to send secure messages. The finding could have important implications for quantum security.
“What makes quantum communication more secure than classical communication is that it makes use of a property of quantum mechanics known as conjugate states,” says Ph.D. student Amita Gnanapandithan, lead author on a paper published in Physical Review Letters.
