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Archive for the ‘genetics’ category

Dec 10, 2018

Bioquark Inc. — Bold Moves Podcast — Ira Pastor

Posted by in categories: aging, bioengineering, biotech/medical, business, DNA, finance, futurism, genetics, innovation, life extension

Dec 9, 2018

Scientists May Have Halted Blindness Caused by This Rare Genetic Disease

Posted by in categories: biotech/medical, genetics, neuroscience

D esigner therapies are treatments tailored to a specific disease, and nowhere is the need greater for new therapies than in a group of nervous system disorders, known as “neurodegenerative diseases.”

Many of these diseases are common and well-known, such as Alzheimer’s or Parkinson’s disease. However, some are very rare, genetic disorders that are the consequence of a defective gene. In all these diseases, a mutant protein that misfolds causes the degeneration and death of neurons. One effective therapeutic strategy is to prevent the rogue protein from ever being made.

Spinocerebellar ataxia type 7 (SCA7) is one such disease in which nerves in different parts of the brain, including the eye, degenerate, which leads to blindness and difficulty walking, speaking, and balancing. SCA7 is dominantly inherited — which means that you just need one bad copy of the mutation to cause disease. The disease occurs when a short section of DNA that encodes ataxin-7 gene is erroneously repeated — like a word in a book printed two or three times. In this case, three chemical units of the DNA sequence — C-A-G — are repeated over and over.

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Dec 8, 2018

Regenerage — SMX Radio — The Net of Regenerative Medicine — Bioquark

Posted by in categories: aging, bioengineering, biotech/medical, business, disruptive technology, DNA, finance, futurism, genetics, life extension
Dr. Joel I. Osorio of RegenerAge Clinic on SMX Radio broadcasting from the Colonia Santa María la Ribera neighborhood of Mexico City -
“LAS NETAS DE LA MEDICINA REGENERATIVA” (The Net of Regenerative Medicine)

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Dec 7, 2018

Genetically Modified People Are Walking Among Us

Posted by in category: genetics

And, so far, they’re just fine. America needs a sober debate about the pros and cons of Crispr instead of a paranoid ban on the technology.

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Dec 7, 2018

FDA Approves Drug That Targets Key Genetic Driver of Cancer

Posted by in categories: biotech/medical, genetics

Imagine one drug that can target and kill malignant cells for some patients with many types of cancer. A new drug called Vitrakvi (larotrectinib), now approved by the U.S. Food and Drug Administration, shows promise of doing just that for both adults and children with a variety of sometimes rare cancers that share one specific genetic mutation.

The mutation, called a TRK fusion, occurs when one of three NTRK genes becomes mistakenly connected to an unrelated gene and ignites uncontrolled growth. By solely targeting this mutation, the drug is designed to turn off growth signaling with a minimum of other toxicities.

According to the drug manufacturer, Loxo Oncology, this specific mutation can occur in a small subset of various adult and pediatric solid tumors ranging from cancers of the appendix, bile ducts, breast, lung, pancreas and thyroid to melanoma, GIST and various sarcomas.

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Dec 6, 2018

Double the stress slows down evolution

Posted by in categories: biotech/medical, evolution, genetics

Neoliberalism slows down evolution! Just kidding…or am I? 🧐😁🤣🙈.


Like other organisms, bacteria constantly have to fight to survive in hostile living conditions. Together with colleagues in Finland, researchers at the Max Planck Institute for Evolutionary Biology in Plön have discovered that bacteria adapt to their environment more slowly and less efficiently as soon as they are exposed to two stress factors rather than one. This is due to mutations in different genes. The slower rate of evolution led to smaller population sizes. This means that evolution can take divergent paths if an organism is exposed to several stress factors.

Bacteria rarely live alone; they are usually part of a community of species that is exposed to various stress factors. They can often react to these factors by adapting to new environmental conditions with astonishing speed. Antibiotics that enter soil and water via and accumulate there in low concentrations can trigger the evolution of resistance in – even though these concentrations are so low that they inhibit only slightly or not at all. However, bacteria do not only have to fight ; they also have to deal with predators. This is why they often grow in large colonies that cannot be consumed by predatory organisms.

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Dec 5, 2018

Bioquark — Electroceuticals — Real Bodies

Posted by in categories: aging, bioengineering, biotech/medical, business, DNA, futurism, genetics, innovation, neuroscience, science
Stefania De Matteo of HealthQe at Real Bodies Milan giving an overview of some of the new bio-physical tools (https://www.youtube.com/watch?v=HwPANPNRY4g) being developed for a 2019 biotech world
With major pharma companies like GSK entering the “electro-ceuticals” space (and groups like RegenerAge Clinic beginning to utilize them in combinatorial protocols) we are seeing a re-emergence of these century old principles back into the mainstream bio-medical discussion

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Dec 5, 2018

12th Jaipur Literature Festival: AI, cli-fi, genetics sessions on line-up

Posted by in categories: genetics, mapping, robotics/AI

https://paper.li/e-1437691924#/&h=AT3mdHzXuCejMgVQDYy6JiVw58…e-BeRlnE2g


“Our world is changing so fast… this year we have sessions on artificial intelligence, genetics and what the future holds for our planet. There is a new term now — cli-fi. We have a beautiful session on cli-fi, on what would happen if bees disappear.

”I feel at this moment in our country it is very very important to give impetus to empirical thinking,” the author of ”Paro: Dreams of Passion” said.

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Dec 5, 2018

In World First, Woman Gives Birth After Receiving Uterus Transplant from Dead Donor

Posted by in categories: biotech/medical, genetics

A team of doctors in Brazil have announced a medical first that could someday help countless women unable to have children because of a damaged or absent uterus. In a case report published Tuesday in the Lancet, they claim to have successfully helped a woman give birth using a transplanted uterus from a deceased donor.

According to the report, the team performed the operation on an unnamed 32-year-old woman in a Brazilian hospital in September 2016. The woman had been born with a rare genetic condition that left her without a uterus, known as Mayer-Rokitansky-Küster-Hauser syndrome, but she was otherwise healthy. The donor was a 45-year-old woman who had suddenly died of stroke; she had had three successful pregnancies delivered vaginally in the past.

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Dec 4, 2018

The FDA just approved a drug that targets cancers based on DNA, rather than where the tumor is in your body

Posted by in categories: biotech/medical, genetics

  • The FDA on Monday approved a new cancer treatment in an unconventional way: not by tumor type, but rather by the genetic mutation the drug targets.
  • The drug, Vitrakvi, was developed by Loxo Oncology in partnership with pharma giant Bayer.
  • It’s only the second time the FDA has approved a cancer drug’s use based on a certain mutation rather than a particular tumor type.

The Food and Drug Administration on Monday took an unconventional approach to approving a new cancer drug.

The drug, Vitrakvi, was developed by Loxo Oncology. It’s the company’s first drug to get approved.

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