Archive for the ‘genetics’ category: Page 3

Nov 10, 2019

The transhuman future is here

Posted by in categories: augmented reality, biotech/medical, genetics, life extension, robotics/AI, transhumanism, virtual reality

The philosophy that we should merge with machines to expand our intelligence and extend life is gaining traction. Design, scientific and technological frontiers are being pushed to redefine nature through AI, AR, biotech, genetics, and VR.

Nov 10, 2019

Will gene editing solve all our problems?

Posted by in categories: bioengineering, biotech/medical, genetics

Many purposes underlie all the genetic projects of our day. Are you aware of them?

Nov 9, 2019

DNA Test Startup Claims It Can Spot Embryos With Low Intelligence

Posted by in categories: biotech/medical, genetics

Questionable startups are claiming to be able to determine how smart a frozen IVF embryo will become if carried to term, and parents are taking the bait.

Genomic Prediction, the most prominent of these companies, offers tests to scan embryos for genetic diseases and other conditions — as well as genetic indicators that a future child will be in the bottom two percent of intelligence.

And MIT Technology Review reports that Genomic Prediction co-founder Stephen Hsu often uses media appearances to discuss future plans for a general intelligence test — something that, with current tech, is extremely unlikely to actually work.

Nov 8, 2019

Modified CRISPR gene editing tool could improve therapies for HIV, sickle cell disease

Posted by in categories: bioengineering, biotech/medical, genetics

City of Hope researchers may have found a way to sharpen the fastest, cheapest and most accurate gene editing technique, CRISPR-Cas9, so that it can more successfully cut out undesirable genetic information.

This improved cutting ability could one day fast-track potential therapies for HIV, and, potentially, other immune conditions.

“Our CRISPR-Cas9 design may be the difference between trying to cut a ribeye steak with a butter knife versus slicing it with a steak knife,” said Tristan Scott, Ph.D., lead author of the study and a staff research scientist at City of Hope’s Center for Gene Therapy. “Other scientists have tried to improve CRISPR cutting through chemical modifications, but that’s an expensive process and is like diamond-coating a blade. Instead, we have designed a better pair of scissors you can buy at any convenience store.”

Nov 8, 2019

How Gene Therapy Is Evolving to Tackle Complex Diseases

Posted by in categories: biotech/medical, genetics

Gene therapy has traditionally been applied to well-understood diseases where a single genetic mutation was to blame. A new generation of technology is expanding the potential of gene therapy to treat conditions that were previously unreachable. Since the first gene therapy clinical trials in the 1990s, the technology has made its way into the market for conditions ranging from blindness to cancer. Gene therapy has the potential to fix any genetic mutation causing disease by inserting a new copy of the faulty gene. However, its reach has historically been limited. We’ve been constrained with the things we.

Nov 7, 2019

Dr. David Sinclair on Informational Theory of Aging, Nicotinamide Mononucleotide, Resveratrol & More

Posted by in categories: biotech/medical, genetics, life extension

David A. Sinclair, PhD, is a professor in the Department of Genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for the Biological Mechanisms of Aging.
Dr. Sinclair’s work focuses on understanding the mechanisms that drive human aging and identifying ways to slow or reverse aging’s effects. In particular, he has examined the role of sirtuins in disease and aging, with special emphasis on how sirtuin activity is modulated by compounds produced by the body as well as those consumed in the diet, such as resveratrol. His work has implications for human metabolism, mitochondrial and neurological health, and cancer.

▶︎ Get the episode’s show notes, timeline, and transcript.

Continue reading “Dr. David Sinclair on Informational Theory of Aging, Nicotinamide Mononucleotide, Resveratrol & More” »

Nov 7, 2019

First use of CRISPR against cancer in patients clears safety hurdles

Posted by in categories: bioengineering, biotech/medical, genetics

The first attempt in the United States to use a gene editing tool called CRISPR against cancer seems safe in the three patients who have had it so far, but it’s too soon to know if it will improve survival, doctors reported Wednesday.

The doctors were able to take immune system cells from the patients’ blood and alter them genetically to help them recognize and fight cancer, with minimal and manageable side effects. The treatment deletes three genes that might have been hindering these cells’ ability to attack the disease, and adds a new, fourth feature to help them do the job.

“It’s the most complicated genetic, cellular engineering that’s been attempted so far,” said the study leader, Dr. Edward Stadtmauer of the University of Pennsylvania in Philadelphia. “This is proof that we can safely do gene editing of these cells.”

Nov 7, 2019

This Scientist Wants to Gene-Hack Hybrid Humans to Survive Mars

Posted by in categories: biotech/medical, genetics, space

If we want to reach Mars, we may have to upgrade our DNA.

Nov 5, 2019

All children to receive whole genome sequencing at birth, under ambitions laid out

Posted by in categories: biotech/medical, genetics, health

All children will be able to receive whole genome sequencing at birth, under ambitions laid out by the Health Secretary.

Matt Hancock said that in future, the tests would be routinely offered, alongside standard checks on newborns, in order to map out the risk of genetic diseases, and offer “predictive, personalised” care.

Ministers have already promised that such tests will be offered to all children diagnosed with cancer by the end of this year.

Nov 5, 2019

Scientists extend mice lifespan 12%

Posted by in categories: biotech/medical, genetics, life extension

Scientists successfully extended the average lifespan of mice by breeding them using embryonic stem cells with extra-long telomeres. The findings are significant because the researchers managed to extend lifespan without genetic modification, and they also shed light on the aging process and techniques that might someday slow it.

The study — published October 17 in Nature Communicationsfocuses on telomeres, which are stretches of DNA found at the end of chromosomes.

Because telomeres protect the genetic material inside chromosomes, they’ve been likened to the plastic tips on the ends of shoelaces. But telomeres have also been compared to bomb fuses, or “molecular clocks,” because they become shorter each time a cell divides, eventually shrinking so much that the cell dies or stops dividing. This shortening of our telomeres is associated with aging, cancer, and death.

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