Sep 5, 2019
LEAF | Life Extension Advocacy Foundation
Posted by Paul Battista in categories: biotech/medical, life extension
Our mission is to promote the advancement of biomedical technologies which will increase healthy human lifespan.
Archive for the ‘life extension’ category: Page 4
Sep 5, 2019
World’s first anti-aging trial gets green-light
Posted by Montie Adkins in categories: biotech/medical, life extension
A 5 year study. In recent years it has been shown to extend the lives of nematodes (or roundworms) by 57% and mice by 6%. In humans, claims abound that metformin-takers are living longer, having fewer cardiovascular episodes and seeing reduced odds of getting cancer.
Groundbreaking TAME trial, which directly targets aging as an endpoint, finally begins this November, reveals lead clinician Dr Nir Barzilai.
Sep 5, 2019
NBC & Phil Noyce Plan Cryonics Drama
Posted by Paul Battista in categories: cryonics, life extension
NBC is developing an untitled cryonics-themed project which hails from writer and executive producer David Slack and filmmaker Phillip Noyce who will direct the pilot and executive produce.
Sony Television produces the series which follows an enigmatic billionaire who has gathered more than 250 people who attempt to cheat death by undergoing cryogenic suspension in hopes that a future breakthrough would someday allow them to be brought back to life.
However, as these people from different moments in time wake up, they soon realise you can’t cheat death without paying a price. Josh Berman and Chris King will also serve as executive producer. Noyce also helmed the pilots of and executive produced ABC’s “Revenge” and FOX’s “The Resident”.
Click on photo to start video.
They’re insidious. They’re lethal, and they’re here to take your life. They’re the hallmarks of aging!
Sep 4, 2019
AgeX Discussion of Aging and Regeneration
Posted by Paul Battista in category: life extension
AgeX CEO Dr. Michael West discusses the technology behind cell aging reversal described in the publication “Toward a Unified Theory of Aging and Regeneration.”
Sep 4, 2019
Transient Telomerase Expression Mediates Senescence and Reduces Cancer Risk
Posted by Steve Hill in categories: biotech/medical, life extension
A joint study by researchers at the National Institutes of Health (NIH) and the University of Maryland (UMD) has revealed a previously undocumented protective function of the telomerase enzyme.
Telomerase is used by somatic cells too
It was thought for a long time that telomerase is only active in certain cell types, such as stem cells, immune cells, and embryonic cells, in order to protect them from aging. Aside from a few cell types and, of course, cancer cells, which are able to hijack the telomerase enzyme in order to replicate uncontrollably, researchers believed that the enzyme is switched off in other types of cells.
Sep 4, 2019
Inside the conference dedicated to reversing human aging
Posted by Paul Battista in category: life extension
Sep 3, 2019
Telomere length and aging‐related outcomes in humans: A Mendelian randomization study in 261,000 older participants
Posted by Paul Battista in categories: genetics, life extension
We estimated associations between measured telomere length (TL) and several aging outcomes by using TL‐associated inherited genetic variants, which are robust to later environmental exposures (confou…
Sep 3, 2019
Cryonics Institute August 2019, 1,991 Members in total (including 177 patients in stasis) & 195 Assoc
Posted by Paul Battista in categories: biotech/medical, cryonics, life extension
Sep 3, 2019
Previously Unknown Protective Role Uncovered for Telomerase in Somatic Cell Aging
Posted by Omuterema Akhahenda in categories: biotech/medical, genetics, life extension
Results from the new study, reported in the Proceedings of the National Academy of Sciences (PNAS) have shown that telomerase is reactivated in normal adult cells at the latter stage of cell aging, and this activity reduces the potential for DNA damage that could lead cells to become cancerous. “This study reshapes the current understanding of telomerase’s function in normal cells,” said Kan Cao, PhD, an associate professor of cell biology and molecular genetics at UMD, who is senior author of the study. “Our work shows, for the first time, that there is a role for telomerase in adult cells beyond promoting tumor formation.
University of Maryland-led team found that telomerase, which immortalizes cancer cells, also prevents tumors and slows a key stage in normal cell death.
