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BioViva focuses on translating this research into therapies.

In the search to extend human lifespan and address age-related diseases, telomerase reverse transcriptase (TERT) stands out as a promising focus of research. This enzyme, known for its role in maintaining telomeres—the protective caps at the ends of chromosomes—offers potential pathways to combat ageing at a cellular level. BioViva, under the leadership of CEO Liz Parrish, is working to transform telomerase-based scientific breakthroughs into tangible therapies aimed at enhancing health and longevity.

What if the secret to slowing down aging was hiding in our brains? A groundbreaking study by researchers at the Allen Institute for Brain Science in Seattle, published in Nature in January 2025, may have uncovered some exciting clues. Using cutting-edge technology, the team analyzed over 1.2 million brain cells from young and aged mice to understand how they change with time. They found that certain cells become inflamed, while others lose critical functions, and all eyes are now on the hypothalamus as a key player in the aging process. These findings deepen our understanding of aging and could pave the way for treatments that keep our brains younger for longer.

Lithium metal, a next-generation anode material, has been highlighted for overcoming the performance limitations of commercial batteries. However, issues inherent to lithium metal have caused shortened battery lifespans and increased fire risks. KAIST researchers have achieved a world-class breakthrough by extending the lifespan of lithium metal anodes by approximately 750% using only water.

Their study is published in the journal Advanced Materials.

Professor Il-Doo Kim from KAIST’s Department of Materials Science and Engineering, in collaboration with Professor Jiyoung Lee from Ajou University, successfully stabilized lithium growth and significantly enhanced the lifespan of next-generation lithium metal batteries using eco-friendly hollow nanofibers as protective layers.

Not a dramatic increase, but a good one.


Loyal, a US biotech startup, has been conducting research and development on LOY-002, a potential drug for extending the lifespan of dogs.

The Guardian reported that the company expects to launch this beef-flavored pill on the market early next year.

The multistep process by which phagocytes engulf these deceased cells without eliciting an inflammatory response is called efferocytosis. Despite significant insights into the fundamental mechanisms of efferocytosis, its implications in disorders such as aging and cancer remain elusive. Upon summarizing and analyzing existing studies on efferocytosis, it becomes evident that efferocytosis is our friend in resolving inflammation, yet it transforms into our foe by facilitating tumor development and metastasis. This review illuminates recent discoveries regarding the emerging mechanisms of efferocytosis in clearing apoptotic cells, explores its connections with aging, examines its influence on tumor development and metastasis, and identifies the regulatory factors of efferocytosis within the tumor microenvironment. A comprehensive understanding of these efferocytosis facets offers insights into crucial physiological and pathophysiological processes, paving the way for innovative therapeutic approaches to combat aging and cancer.

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Researchers at the Allen Institute have identified a specific brain region in mice where aging triggers significant changes in numerous cell types. The study also pinpointed which cell types undergo the most profound transformations.

This new information, published in the journal Nature, points toward potential approaches for slowing or controlling the aging process in the brain.

The research was focused on numerous glial cell types – the brain’s “support cells” – that demonstrated considerable shifts in gene activity with age. Among the cells most affected were microglia, border-associated macrophages, oligodendrocytes, tanycytes, and ependymal cells.

“The ultimate goal is to extend healthspan—meaning the number of years aging adults live healthy lives and enjoy overall well-being by compressing the frailty and disability that comes with aging into a shorter duration of time near the end of life,” says Andrew Brack, PhD, the PROSPR Program Manager.

The new venture will be building on some of the work that the National Institute of Aging (NIH) has been working on and will be working in collaboration with various organizations in the biotechnology industry as well as some unspecified regulators to accelerate the development, testing, and availability of new therapeutic that targets human healthspan.

It is hoped that the new initiative, along with positively impacting the healthspan of Americans, will also help to enhance the economy across the nation.

Largest brain aging study points to possible connections between diet, inflammation, and brain health.

Scientists at the Allen Institute have discovered specific types of brain cells in mice that experience significant changes as they age. They also identified a distinct “hotspot” where many of these changes are concentrated. Published today (January 1) in Nature, these findings could lead to the development of therapies aimed at slowing or managing the brain’s aging process.