Meet the centenarian professor who is a living example of health, fitness and everything good. Popularly known as the nutrition professor, Dr. John Scharffenberg was born on December 15, 1923 in China. A Harvard University alumnus, Dr. Scharffenberg’s interview on longevity and leading a healthy life is very popular on social media. Here are a few risk factors he has warned against in several interviews:
Several multi-cancer GWAS loci within the region encoding telomerase reverse transcriptase (TERT) have been identified. Here, the authors explore the locus within TERT intron 4, link it with a variable number tandem repeat (VNTR), and investigate its biological significance and role in cancer.
Bryan Johnson took ketamine and monitored his brain activity for 15 days, recording the experience and sharing about it on X.
Johnson is a 47-year-old longevity-obsessed entrepreneur, known for sharing biohacking content across his social media channels. His most recent health experiment involved treatment with the popularized horse tranquilizer.
As he shared in a tweet, he wanted to test what happens to the brain before, during, and after ketamine treatment.
Ketamine has gained popularity as a fast-acting treatment for depression, PTSD, and chronic pain. Unlike traditional antidepressants, it works quickly by targeting the brain’s glutamate system to restore neural connections.
To monitor his brain activity, Johnson used his self-invented Kernel Flow—a form of non-invasive brain interface technology worn on the head.
Research shows a high-magnesium diet could slow brain aging and lower dementia risk.
A study from the Australian National University shows that increased magnesium intake may help protect against age-related brain decline, particularly benefiting women.
Researchers analyzed data from over 6,000 participants aged 40–73, tracking their dietary magnesium consumption and its effects on brain volume and white matter lesions. Those consuming more than 550 mg of magnesium daily had brains appearing nearly a year younger by age 55 compared to those with lower intake.
The study also found that postmenopausal women experienced the greatest neuroprotective benefits, possibly due to magnesium’s anti-inflammatory properties.
Magnesium, found in foods like leafy greens, nuts, seeds, legumes, and whole grains, has long been known for its health benefits, but this research highlights its potential role in dementia prevention. With no cure for dementia, experts stress the importance of dietary strategies for brain health.
Graying hair is a hallmark of aging, often considered an inevitable part of growing older. However, recent research from Nagoya University in Japan led by Masashi Kato and Takumi Kagawa suggests that an antioxidant might suppress this process. The researchers identified luteolin, an antioxidant found in vegetables including celery, broccoli, carrots, onions, and peppers, as being a potential anti-graying agent. Their findings pave the way for potential applications in human hair care.
The researchers’ study focused on three antioxidants—luteolin, hesperetin, and diosmetin—to assess their anti-graying effects in mice that were bred to go gray like humans. The difference was startling, the mice that received luteolin retained their black fur, even as their cage mates’ fur turned gray, regardless of whether the luteolin was given externally or internally.
“This result was surprising,” Professor Kato said. “While we expected that antioxidants may also have anti-graying effects, only luteolin, not hesperetin or diosmetin, demonstrated significant effects. This finding suggests that luteolin may have a unique medicinal effect that prevents graying.”
In 2025, Vetek Association is a founding partner in organizing several international conferences. In addition to the main longevity event in Israel – the Longevity Nation conference that will take place in Bar-Ilan University, on June 25–26 https://longevitynation.org/ Registration https://longevitynation.org/register-and-donate/
And community meetups in Israel https://www.longevityisrael.org/meetups/.
Gutierrez and Tyler investigate the limits of replicative lifespan in yeast. The authors show that nucleolar expansion during aging is a mortality timer. Enlargement of nucleoli beyond a defined size alters their biophysical properties; normally excluded DNA repair protein enter, causing aberrant rDNA recombination, genome instability and death.
Interesting item on biological clocks, and other things.
BiOptimizers Magnesium Breakthrough 10% with code Modern10 https://bioptimizers.com/modern. This video brought to you by BiOptimizers.
Here Liz talks about her personal experience with gene therapy and the innovations, the state of the industry and what the future holds. The therapies exist why is it so difficult to make them available!?
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There are a multitude of products for sale that promise the appearance of eternal youth by erasing wrinkles or firming up jaw lines; but what if we could truly turn back time, at the cellular level? Now, researchers from Japan have found a protein that may do just that.
In a study published this month in Cellular Signaling, researchers from Osaka University have revealed that a key protein is responsible for toggling between ‘young’ and ‘old’ cell states.
As we age, older, fewer active cells, known as senescent cells, accumulate in multiple organs. These cells are noticeably larger than younger cells, and exhibit altered organization of stress fibers, the structural parts of cells that help them move and interact with their environment.