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Archive for the ‘life extension’ category: Page 8

Jan 22, 2020

Dmitry Itskov on the Philosophy of Immortality

Posted by in categories: futurism, life extension

Watch it 👇.


MOTHERBOARD met up with Russian billionaire Dmitry Itskov at his Global Future 2045 Conference in New York City to talk about immortality, spirituality, and the coming age of cybernetic avatar-based living.

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Jan 22, 2020

Researchers Identify Gene with Functional Role in Aging of Eye

Posted by in categories: biotech/medical, life extension

In mouse studies, a “methylation clock” on the ELOVL2 gene ticks toward impaired vision, but when gene expression was boosted, age-related visual function improved.


A lengthy-named gene called Elongation of Very Long Chain Fatty Acids Protein 2 or ELOVL2 is an established biomarker of age. In a new paper, published online January 14, 2020 in the journal Aging Cell, researchers at University of California San Diego School of Medicine say the gene appears to play a key role in age-associated functional and anatomical aging in vivo in mouse retinas, a finding that has direct relevance to age-related eye diseases.

Specifically, the research team, led by senior author Dorota Skowronska-Krawczyk, PhD, assistant professor in the Viterbi Family Department of Ophthalmology at UC San Diego Shiley Eye Institute, found that an age-related decrease in ELOVL2 gene expression was associated with increased DNA methylation of its promoter. Methylation is a simple biochemical process in which groups of carbon and hydrogen atoms are transferred from one substance to another. In the case of DNA, methylation of regulatory regions negatively impacts expression of the gene.

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Jan 22, 2020

What Neuroscience Can Teach Us About Aging Better

Posted by in categories: life extension, neuroscience

“A neuroscientist explains how our brains age and provides tips for aging with more vitality and happiness.”

https://greatergood.berkeley.edu/topic[/li

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Jan 21, 2020

AgeX Therapeutics anticipates a ‘revolution’ in aging in next 10 years

Posted by in categories: biotech/medical, life extension

AgeX Therapeutics Inc (NYSEAMERICAN: AGE) CEO Michael West sat down with Proactive’s Christine Corrado at the Biotech Showcase 2020 in San Francisco. The Alameda, California biotechnology company is developing a cell therapy treatment for metabolic disorders such as Type 2 diabetes.

Jan 20, 2020

Against All Odds

Posted by in categories: biotech/medical, life extension

Jane McLelland beat cervical, lung, and blood cancers using the missing link to defeat cancer: starving it. She is partnering with Life ExtensionÂź to help other patients achieve the same results.

By Laurie Mathena.

Jan 20, 2020

Aubrey de Grey, CSO, SENS, “Scientists, check — Investors, check — Next up, policy makers”

Posted by in categories: biotech/medical, life extension, policy

After getting a considerable success in convincing scientists and investors, in the last decades, that undoing aging through a damage repair approach is possible and desirable, Aubrey de Grey is turning his advocacy efforts to politicians. In this video, he explains why.


https://thelongevityforum.com/
Aubrey de Grey delivers a keynote on the next steps for longevity for policy makers.

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Jan 18, 2020

How the Ginkgo biloba achieves near-immortality

Posted by in category: life extension

Jan 17, 2020

Antiaging Treatments that are Closest to FDA Approval

Posted by in categories: biotech/medical, life extension

There are a few dozen antiaging rejuvenation treatments that are progressing through pre-clinical and clinical trials.

Lifespan.io is tracking the antiaging rejuvenation treatments on a rejuvenation roadmap.

Two treatments are in phase 3 clinical trial.

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Jan 17, 2020

Stage is set to develop clinically relevant, senescence-based biomarkers of aging

Posted by in categories: biotech/medical, life extension

Researchers at the Buck Institute have extensively profiled the various inflammatory signals given off by senescent human cells and have generated a curated database available for use in the field.


Senescent cells, which stop dividing under stress, are long- recognized drivers of multiple diseases of aging. Mouse studies have shown that targeted removal of these cells and the inflammatory factors they secrete, known as the senescence-associated secretory phenotype (SASP), has beneficial results on multiple organ systems and functions. Success in the laboratory has given rise to companies and research projects aimed at developing either senolytics, drugs that clear senescent cells, or senomorphics, drugs that suppress the SASP. But drug development and clinical utilization require simple, reliable biomarkers to assess the abundance of senescent cells in human tissues. Publishing in PLOS Biology, researchers at the Buck Institute have extensively profiled the SASP of human cells and have generated a curated database available for use in the field.

“The stage is now set for the development of clinically-relevant biomarkers of aging,” said Judith Campisi, Ph.D., Buck professor and one of the senior authors on the paper. “This will speed efforts to get safe and effective drugs into the clinic and, in the long term, could enable physicians to give patients a clear read-out of how well, or poorly, their various tissues and organs are aging.”

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Jan 16, 2020

Brain Freeze: Russian Firm Offers Path to Immortality for a Fee

Posted by in categories: cryonics, life extension, neuroscience

The freezing procedure, called cryonics, costs $36,000 for a whole body and $15,000 for the brain alone.

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