Even a huge snowpack during the coming winter would only give the river basin states less than two years of storage before reservoirs returned to historic lows.
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Reading and writing neural activity with Neuropixels Opto probes
High-density electrophysiology devices allow neuroscientists to observe spikes from large populations of neurons, and optogenetics allows them to drive or suppress those spikes. We show that a single device can combine these two capabilities, providing a high-resolution means to both read and write neural activity in the living brain.
What If Scientists Already PROVED We’re In A Simulation?| Truth By Lisa Randall
If Scientists Already PROVED We’re In A Simulation?
Bell’s theorem. Maldacena’s holographic proof. Wheeler’s participatory universe.
Three independent bodies of peer-reviewed physics — all pointing at the same unsettling answer.
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Bell’s theorem. Maldacena’s holographic proof. Wheeler’s participatory universe.
Three independent bodies of peer-reviewed physics — all pointing at the same unsettling answer.
What if the simulation hypothesis isn’t a thought experiment? What if the physics we already have — quantum entanglement, the holographic principle, the measurement problem — is the proof?
In this video, Harvard theoretical physicist Lisa Randall walks through the three experiments and mathematical proofs that, taken together, describe a universe that functions in every measurable way like a simulation. Not as metaphor. As structure.
We cover:
→ Alain Aspect’s 1982 Bell test experiment and what it actually proved about local reality.
→ The Bekenstein-Hawking holographic bound — why information scales with surface area, not volume.
→ Maldacena’s AdS/CFT correspondence — the proof that a 3D universe is dual to a 2D information system.
→ Wheeler’s delayed choice experiment and the participatory universe.
→ What the fine-tuning problem looks like inside a simulation framework.
→ Why you — the observer — are not peripheral to the physics. You are part of the mechanism.
This is Episode 1 of The Proof Series — a weekly deep-dive into peer-reviewed science that challenges everything you think you know about reality.
New episode every Thursday.
— Lisa Randall is a theoretical physicist and professor at Harvard University, author of Warped Passages and Dark Matter and the Dinosaurs, and one of the most cited physicists alive.
#SimulationTheory #QuantumPhysics #HolographicUniverse.
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00:00 — The proof nobody is talking about.
01:10 — What \
This Giant Ring In Space Poses A Massive Problem For Cosmology
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Scientists say that they’ve just detected a massive cloud of gas some 3 billion lightyears in diameter, floating in space roughly 7 billion light years away from us. This is pretty cool, but the problem is that our current models of the universe say that it (and other massive structures like it) just shouldn’t exist. Let’s take a look.
Paper: https://arxiv.org/abs/2604.
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NIH-funded study suggests that testosterone suppresses brain tumor growth in males
Findings may warrant exploration of the hormones as glioblastoma treatment.
In a new National Institutes of Health (NIH)-funded study, scientists at Cleveland Clinic discovered that hormones associated with male development may play a key role in limiting the growth of brain tumors in men. The research team found that the loss of androgen hormones, such as testosterone, in a preclinical model of glioblastoma drove tumor growth by inducing local inflammation and triggering the production of stress hormones. In an analysis of data from more than 1,300 men with glioblastoma, the authors found that supplemental testosterone was significantly associated with improved survival, which was consistent with their preclinical experiments.
“This outcome is a welcome surprise and may potentially offer a lead for new treatments for a kind of cancer that is deadlier in men,” said Anthony Letai, M.D., Ph.D., director of NIH’s National Cancer Institute (NCI).
Zoltan Istvan: The Transhumanist Wager Is A Choice We’ll All Have To Make
Thirteen years ago, I sat down with a writer who had just published his first novel.
It was Zoltan Istvan’s very first media interview as a book author.
The book was The Transhumanist Wager. The question behind it was simple and almost unbearable: what would you do, and what would you give up, to live forever?
I loved half of it. I argued with the other half. That tension is exactly why I think it still matters.
Zoltan built his story out of Plato and Nietzsche, out of Thomas More’s Utopia and Zen Buddhism, then wrapped it all in an Atlas Shrugged plot of lone heroes and evil states. The philosophy is sophisticated. The framing is stark. The contradictions are not a flaw. They are the point.
One line from our conversation has stayed with me for more than a decade: