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Scientists Reveal How Cells Tame One of Biology’s Most Dangerous Metals

Polyamines may protect cells from toxic iron buildup by keeping reactive iron under control.

Iron keeps cells alive, but when too much of it remains chemically reactive, the same metal can become destructive. Excess free iron can drive reactions that damage DNA, proteins, and cell membranes, creating a problem cells must constantly control.

Whitehead Institute Member Ankur Jain, former postdoc Whitney Henry, and graduate student Pushkal Sharma have identified an unexpected part of that protective system: small molecules known as polyamines.

Scientists Find a Clue to Making Brain Stimulation More Reliable

The brain’s activity immediately before stimulation may help predict its response and improve the consistency of neuromodulation.

The same brain stimulation can produce very different responses depending on when it is delivered.

A study published in Brain Stimulation, using detailed brain recordings hosted by EBRAINS, suggests that the brain’s activity immediately before stimulation can explain much of this variation and may eventually help make neuromodulation therapies more dependable.

Researchers Solve Two Major Problems Holding Back SiC Electronics

A new bottom gate design takes advantage of the intrinsic properties of SiC.

For more than 20 years, silicon carbide – SiC – has been viewed as a promising material for electronics that must function in extreme environments. Yet despite years of research, that promise has rarely translated into practical devices. Researchers at Kyoto University are now trying to move the field beyond that barrier.

“We believe the lack of development is because the research community has been trying to apply silicon-era thinking to a fundamentally different material,” says first author Mitsuaki Kaneko.

Physicists Hunted a Mysterious Particle — and Found Two Unexpected Structures Instead

A first attempt to produce a mysterious strangeonium state using a photon beam yielded important and unexpected results.

Physicists have spent decades trying to organize the growing collection of subatomic particles, yet some of the most unusual discoveries still resist simple classification. At the U.S. Department of Energy’s Thomas Jefferson National Accelerator Facility, researchers have now detected evidence for two unexpected structures that could help clarify this increasingly complicated landscape.

The signals may shed light on a puzzling class of particles called XYZ states. These objects do not fit comfortably within the conventional picture of particles built from quarks, the elementary constituents of matter. For the first time at Jefferson Lab, two such signals were observed when a beam of high-energy photons struck a proton target.

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