This is ~23 minute talk overviewing our recent results and the way we think about aging and longevity. It was for a conference with quite short speaking slots so I had to talk fast… Longer talk coming with more data but this outlines some ideas and overviews our published recent work on aging.
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Designing a Generational Ship (Proxima Centauri b)
To build a Proxima Centauri b generational ship; designed to protect the life aboard during the 100 year journey from Earth; designed to build the first structures of the settlement on the surface of the new planet.
✧ Find me on Substack where I write sci-fi story essays: J.Barry / Between Worlds.
https://jbarrybetweenworlds.substack… The fourth volume of ‘The Encyclopedia of the Future’ is now available on my Patreon. / shop ✧ The Garden Telescope (and Other Short Stories) Ebook is also available to Patreon members, or as a single purchase download Visit my Patreon here:
/ venturecity Created by: J. Barry — Book recommendations on artificial intelligence, future technology and innovations, and sci-fi stories (affiliate links): • Superintelligence: Paths, Dangers, Strategies https://amzn.to/3j28WkP • Life 3.0: Being Human in the Age of Artificial Intelligence https://amzn.to/3790bU1 • The Expanse: https://amzn.to/3Q0mG61 • The Hitchhikers Guide to the Galaxy: https://amzn.to/3kNFSyW — Other videos to watch: 1. The 100 Year Journey to Proxima Centauri b
• The 100 Year Journey to Proxima Centauri B… 2. The First 10,000 Days on Proxima Centauri b
• The First 10,000 Days on Proxima Centauri… 3. TIMELAPSE of Future Space Stations
• TIMELAPSE of Future Space Stations.
✧ The fourth volume of ‘The Encyclopedia of the Future’ is now available on my Patreon.
/ shop.
✧ The Garden Telescope (and Other Short Stories) Ebook is also available to Patreon members, or as a single purchase download.
Visit my Patreon here: / venturecity.
Created by: J. Barry.
Book recommendations on artificial intelligence, future technology and innovations, and sci-fi stories (affiliate links):
• Superintelligence: Paths, Dangers, Strategies https://amzn.to/3j28WkP
• Life 3.0: Being Human in the Age of Artificial Intelligence https://amzn.to/3790bU1
• The Expanse: https://amzn.to/3Q0mG61
• The Hitchhikers Guide to the Galaxy: https://amzn.to/3kNFSyW
Other videos to watch:
They Just Shrunk AI Data Centers by 10,000x
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Timestamps:
00:00 — Why Superconductors?
10:10 — The Breakthrough.
My Podcast on Apple: https://podcasts.apple.com/at/podcast…
My Podcast on Spotify: https://open.spotify.com/show/3drr7A8… Let’s connect on LinkedIn: / anastasiintech Newsletter: https://anastasiintech.substack.com Instagram:
/ anastasi.in.tech Patreon:
/ anastasiintech.
Let’s connect on LinkedIn: / anastasiintech.
Newsletter: https://anastasiintech.substack.com.
Instagram: / anastasi.in.tech.
Patreon: / anastasiintech.
Artificial ‘leaf’ powers wireless biomedical device
Plants convert light into energy efficiently through photosynthesis—an ability that scientists and engineers still struggle to match with electronic devices. Recently, researchers have looked beyond traditional semiconductor materials to create devices using a promising class of materials called nanoplasmonics. These tiny metal structures can absorb and concentrate optical energy and generate energetic charge carriers.
In a new study, researchers from the University of Chicago Pritzker School of Molecular Engineering (UChicago PME) and Department of Chemistry developed a nanoplasmonic “leaf,” a wireless bioelectronic device they used to stimulate nerves and pace heartbeats in an animal model.
The team also showed that their material could be used as a computer-like sensing platform, where users can interact with the screen using invisible light—a potentially secure way to transmit information.
Some patient groups are far more vulnerable to near-perfect privacy attacks from medical AI
From detecting pneumonia on a chest X-ray to assessing whether a dark spot on the skin is benign or malignant, medical AI systems are playing an increasingly important role in clinical diagnosis. Unfortunately, the models used to train these AI systems are often victims of cyberattacks, specifically membership inference attacks (MIAs), which can lead to people’s personal information being stolen or revealed.
In a recent study, researchers conducted a first-ever patient-level privacy audit to see how easily individual patients could be identified from the underlying data used to train medical AI models.
At first glance, an AI model may appear to protect everyone’s privacy equally well, but a closer look reveals a different story. Researchers found that attackers can identify certain individual patients with near-perfect accuracy, exposing a hidden unfairness in privacy.
Detect Dangerous Gases in Seconds With New Technology
A groundbreaking method known as coherently controlled quartz-enhanced photoacoustic spectroscopy has been developed to detect and identify gases at very low concentrations rapidly.
This new technique, with promising applications in environmental monitoring, early cancer detection, and chemical process safety, allows for comprehensive gas analysis in mere seconds, a process that traditionally took much longer.
Enhanced sensitivity in trace gas detection.
ROS-producing enzymes guide plant cell division and tissue patterning, gene-editing study shows
Reactive oxygen species (ROS) produced naturally during cellular metabolism often cause oxidative damage to cells. However, these molecules also play an important role in normal cellular signaling. While ROS are established as essential signaling molecules in various organisms, their precise role in basic plant development and morphogenesis remains unclear.
A family of enzymes known as NADPH oxidases (NOXs) generates ROS that act as physiologically important signaling molecules. In plants, the NOX enzymes are known as respiratory burst oxidase homologs (RBOHs), which are implicated in diverse physiological processes. However, their contribution to plant development, including cell proliferation and ordered morphogenesis, has remained insufficiently understood.
To address this gap, a team of researchers led by Professor Kazuyuki Kuchitsu from the Department of Applied Biological Science at Tokyo University of Science (TUS) in Japan conducted a study.
Combination of Neuronavigation-Guided Focused Ultrasound… : Neurosurgery
This was a prospective, single-arm, open-label pilot trial. The primary end point was 6-month progression-free survival (PFS). Disease progression was assessed according to the Response Assessment in Neuro-Oncology criteria by independent radiological review. Radiological response was evaluated using fluid-attenuated inversion-recovery sequences to compare FUS-exposed vs nonexposed regions. Plasma cell–free DNA (cfDNA) concentrations were measured before and after FUS treatment.
RESULTS:
Between July 2020 and August 2023, 6 patients received a median of 14.5 sessions of biweekly FUS-BEV (10 mg/kg). The median PFS was 11 months, with a 6-month PFS rate of 66.7%. The only FUS-related adverse event was transient scalp heating (grade 1; 1.9%). A fluid-attenuated inversion recovery normalization effect emerged within 1 month after treatment. Plasma cfDNA increased significantly post-FUS, with total cfDNA rising 2.03 ± 0.76-fold, EGFR cfDNA 1.77 ± 0.76-fold, and HMBS cfDNA 1.68 ± 0.66-fold.
Role for NANOG in human embryogenesis
New research has shown that a genome editing technique can be used to alter a single gene in human embryonic cells, enabling the study of very early human development in unparalleled detail.
The technique, called base editing, is a more precise version of the genome editing technique CRISPR/Cas9. It can change a single nucleotide base pair — the basic building block of DNA — within a human genome of approximately 3 billion base pairs.
Using base editing, the researchers blocked a gene called NANOG in very early-stage human embryos, and found that the cells of the early embryo could not develop into more specialised pluripotent cells called the epiblast — which later form the body.