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Brain-inspired chip could reduce AI energy use by 70%

Replicating the brain’s capabilities, an impossible task, may theoretically require thousands of H100, one of NVIDIA’s most powerful GPUs. At 700 watts per chip, we are looking at power consumption in the megawatt range. The brain runs on 20 watts. Scientists have taken inspiration from this remarkable organ to create chips that could cut conventional energy use by 70%.

Researchers at the University of Cambridge have developed a new brain-inspired nanoscale device that they say could dramatically reduce the enormous energy demands of artificial intelligence hardware. The team created an ultra-low-power “memristor”: a device that can both store and process information in the same location, much like synapses in the human brain.

In conventional computing architectures, memory and processing units are physically separated, requiring data to shuttle back and forth between these units for every task. This seemingly simple process consumes enormous amounts of electricity and is a significant contributor to AI’s exploding power demands.

Scientists discover the “Goldilocks” secret behind life on Earth

Earth may be habitable because it got unbelievably lucky with its chemistry from the very start.

Earth may have won a cosmic chemistry lottery. Researchers found that during the planet’s earliest formation, oxygen had to be in an extremely narrow “Goldilocks zone” for two life-essential elements, phosphorus and nitrogen, to stay where life could use them. Too much or too little oxygen, and those ingredients could be lost or trapped deep inside the planet. This could reshape the search for life by showing that water alone is not enough.

Life cannot begin on a planet unless certain chemical elements are available in large enough amounts. Two of the most important are phosphorus and nitrogen. Phosphorus helps build DNA and RNA, which store and pass along genetic information, and it also plays a key role in how cells manage energy. Nitrogen is a major part of proteins, which are essential for building cells and helping them function. Without enough phosphorus and nitrogen, life cannot emerge from nonliving matter.

High trust in AI leaves individuals vulnerable to “cognitive surrender,” study finds

People are increasingly outsourcing their thinking to artificial intelligence, bypassing critical reflection entirely. New research reveals that this “cognitive surrender” inflates confidence and causes users to blindly adopt algorithm-generated answers, even when the software is wrong.

How do you study something you can never step outside of?

Studying the thing you can never step outside of and look back at is the fundamental problem facing every cosmologist who has ever looked up at the night sky. The Universe is not a laboratory you can peer into from above, it’s the thing you are already inside. The only way to truly test your ideas about how it works is to build a copy of it, run the clock forward from the Big Bang, and see if what emerges matches what your telescopes are actually telling you.

That is exactly what the FLAMINGO project has been doing. And this week, its creators made the results available to the entire world.

An international team of astrophysicists, led by researchers at Leiden University in the Netherlands, has released one of the largest cosmological simulation datasets ever produced. The archive contains more than 2.5 petabytes of data (roughly equivalent to half a million high definition films) and is free to access for researchers anywhere on the planet.

MRI reveals cerebrospinal fluid shifts after mild brain injury

Researchers at University of Tsukuba have found that cerebrospinal fluid (CSF) microdynamic motion shows region-specific alterations after mild traumatic brain injury (TBI). Using a specialized magnetic resonance imaging (MRI) technique, the team noninvasively visualized these CSF changes, which have been difficult to quantify with conventional imaging. The approach is expected to advance the understanding of the relationship between post-traumatic brain conditions and cognitive function. The study is published in Frontiers in Neuroscience.

The brain contains cerebrospinal fluid (CSF), which protects neural tissue and helps clear metabolic waste. Rather than being static, CSF exhibits continuous subtle motion, and this motion is thought to be closely linked to brain health. However, little has been known about how CSF motion is altered after a mild head injury.

The researchers employed a specialized magnetic resonance imaging (MRI) technique known as intravoxel incoherent motion (IVIM) MRI to evaluate CSF microdynamic motion through the incoherent movement of water molecules. The results showed that, after mild traumatic brain injury (TBI), CSF motion increased in some brain regions and decreased in others.

T cells secrete DNA to boost the immune system’s cancer-fighting ability

Activated immune cells secrete tiny capsules bearing DNA that can enter other immune and tumor cells to stimulate the body’s defense systems, according to a study led by investigators at Weill Cornell Medicine. The discovery extends the scientific understanding of the immune system, identifies a new strategy for boosting immunity against cancers and potentially offers a new tool for delivering genetic payloads to other cells.

Most animal cells secrete tiny capsules known as extracellular vesicles—nanoscale, membrane-bound particles—whose cargo can include proteins, snippets of DNA and other molecules. In the new study, published April 30 in Cancer Cell, the researchers discovered that vesicles secreted by activated T cells —major weapons of the immune system—carry DNA that enters immune cells and nearby tumor cells to enhance the immune response against the tumor. Preclinical experiments showed that this vesicle-associated DNA could be useful therapeutically, boosting T cell attacks against tumors that otherwise evoke little or no immune response.

“These findings reveal a natural mechanism for treating immunologically silent tumors and other diseases that stem from insufficient immune surveillance,” said study co-senior author Dr. David Lyden, the Stavros S. Niarchos Professor in Pediatric Cardiology and a member of the Gale and Ira Drukier Institute for Children’s Health and the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine.

Deciphering the Nanoscale Architecture of Presynaptic Actin Using a Micropatterned Presynapse-on-Glass Model

Prefrontal cortex encodes behavior states decoupled from motor execution.

By tracking the natural actions of freely moving rats, Välikangas et al. show that prefrontal cortex encodes abstract behavioral states rather than low-level physical aspects of movement. Prefrontal activity anticipates behaviors and operates on slow timescales, suggesting that it represents high-level goals rather than moment-to-moment motor output.

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