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Sleep variability linked with sleep apnea and hypertension

Over 70 million Americans wear digital activity trackers (DATs) to record their sleep, steps and heart rate. A new study from Scripps Research found that these devices could also provide insight into even more, including individual health risks like obstructive sleep apnea (OSA) and high blood pressure.

The findings, published in the Journal of Medical Internet Research on December 3, 2025, used DATs to identify an association between sleep variability—the night-to-night fluctuation of when an individual falls asleep and wakes—and their risk of developing sleep apnea and hypertension. This research joins a growing body of evidence that DATs could become more useful clinical tools to assess health risks in the near future.

“Data from digital activity trackers provides a unique way to detect meaningful health patterns from the devices that people already own,” says Stuti Jaiswal, senior author and assistant professor at Scripps Research, who is also a faculty hospitalist at Scripps Clinic. “Digital health studies have been gaining acceptance over the past decade, and we’re now demonstrating what these technologies can reveal about how sleep influences cardiovascular health.”

A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology

This multicenter study demonstrates use of dried and capillary blood as a minimally invasive, scalable approach for Alzheimer’s biomarker testing in research, with potential as a widely scalable population-based research approach, especially in resource-limited settings.

Kidney Stone Link to Cancer Risk Increased in Recent Studies

A systematic review and meta-analysis found that people with kidney stones have about twice the risk of developing kidney cancer compared with those without stones, across patient subgroups. The findings support closer cancer surveillance in patients with a history of kidney stones and further research into shared disease mechanisms, given the prevalence of kidney stones and the aggressive nature of kidney cancer.


A new meta-analysis further supports the previously reported link between kidney stones and an increased risk for kidney cancer, with a stronger relationship observed in newer studies.

TMAO Is Bad For Health, But Can Be Reduced (21-Test Analysis)

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