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Discovery of brain-body connection offers clues for Parkinson’s and alcohol use disorder

When danger lurks, instinct keeps us safe. It compels us to run from a burning building or wrestle a knife-wielding attacker to the ground. It also adjusts our body physiology to support these behaviors.

Survival helps explain why. But the mechanisms that link the brain and the body—the “switch” between rest and action—have long been shrouded in mystery.

A research team at Rutgers University-New Brunswick thinks they may have identified a key mechanism, and the findings may hold important clues to how diverse neurological conditions, such as alcohol use disorder and Parkinson’s, could be diagnosed and treated.

NASA Welcomes Paraguay as 67th Artemis Accords Signatory

The Republic of Paraguay signed the Artemis Accords on Thursday during a ceremony in Asunción, becoming the latest nation to commit to the shared principles guiding civil space exploration.

“Today, I am proud to welcome Paraguay as the 67th signatory to the Artemis Accords,” said NASA Administrator Jared Isaacman. “They join an ever-growing coalition of like-minded nations committed to the peaceful, transparent, and responsible exploration of space. Established by President Trump in his first term, the Artemis Accords provided the principles for how we explore the Moon, Mars, and beyond. Now, with his national space policy, we are putting the Artemis Accords into practice with our Moon Base. We are creating opportunities for all Artemis Accords signatories, including Paraguay, to join us on the lunar surface and advance our shared objectives in this next era of exploration.”

U.S. Embassy Asunción Chargé d’Affaires ad interim Aaron Pratt shared Isaacman’s remarks during the ceremony. Minister President of the Paraguayan Space Agency Osvaldo Almirón Riveros signed on behalf of Paraguay.

Our Extropian Future, with Natasha Vita-More

Our extropian future: natasha vita-more on AI, nanotechnology, mind uploading, and the birth of transhumanism.

What happened to the future we dreamed about on the Extropian mailing list 30 years ago? Did we get the timelines wrong, or was the architecture of our thinking correct? In this compelling follow-up to the conversation with Max More, Giulio Prisco sits down with Natasha Vita-More—futurist, designer, and co-founder of the Extropian movement—to assess the state of \.

Stanford’s new chip boosts light 100x with surprisingly low energy

Researchers at Stanford have developed a compact optical amplifier that dramatically boosts light signals using very little power. By recycling energy inside a looping resonator, the device achieves strong amplification with minimal noise and wide bandwidth. Its efficiency and small size mean it could run on batteries and be integrated into consumer electronics. This breakthrough could enable faster communications and more powerful optical technologies.

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