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Scientists Created a Subatomic Particle That Defies Our Understanding of Physics

For decades, every known atomic and nuclear system has relied on at least two fundamental forces working in concert: the strong force binds protons and neutrons inside the nucleus, while electromagnetism holds electrons in orbit around it. Now, an international team of physicists has found the first experimental evidence of a nuclear system bound exclusively by the strong force—confirming a theoretical prediction made twenty years ago and opening a new window onto how matter acquires mass.

Creating a system held together by only one force required a particle with a special property: no electric charge. Ordinary atoms can’t do the job because their components—protons and electrons—are electrically charged, so electromagnetism is always in play. The Standard Model of particle physics, which describes three of the four fundamental forces (the strong force, the weak force, and electromagnetism —gravity isn’t included), predicts that electrically neutral mesons should be able to bind to a nucleus through the strong interaction alone. The eta prime meson (η′) is the ideal test case: it carries no electric charge, so it can’t be bound electromagnetically, and its unusually large mass makes it a uniquely sensitive probe of the strong force’s inner workings.

Generalization Dynamics of LM Pre-training

An AI has a limited amount of “capacity” (brainpower). Early in training, it develops quick, shallow circuits to memorize data because that’s the easiest way to get the right answer. Later, it develops complex circuits for actual reasoning. Because space is limited, these two internal systems are constantly competing for control. Whichever type of data the AI happens to be reading in a specific moment determines which circuit wins the battle.


People typically assume that LMs stably mature from pattern-matching parrots to generalizable intelligence during pre-training. We build a toy eval suite and show this mental model is wrong: throughout pre-training, LMs frequently and suddenly hop between parrot-like and intelligence-like modes, i.e. distinct algorithms implemented by distinct circuits. We call this mode-hopping. Across our suite, LMs can suddenly latch onto memorized or in-context patterns instead of in-context learning, use System 1 instead of System 2 thinking, pick up what sounds true instead of what is true, fail at multi-hop persona QA, out-of-context reasoning, and emergent misalignment — then just as suddenly revert and generalize. Mode-hopping is not explained by standard optimization dynamics: it is locally stable and can not be fixed by checkpoint averaging. We instead think of it as a capacity allocation problem: in a capacity-bounded model, generalizable circuits must compete with the shallow ones learned early in training, and the data in each pre-training window decides which circuits win. Our suite provides a cheap set of pre-training monitors and a new lens on generalization. Building upon our insights, we demonstrate three applications: (i) select intermediate pre-training checkpoints that strongly generalize reasoning and alignment, better than the final pre-or mid-training checkpoints, (ii) select pre-training data that controls and stabilizes generalization dynamics, and (iii) test prior generalization predictors, falsifying the monolithic belief that “simpler solutions generalize better”

Building general AI without generalization is doable but meh. We want an intelligence that learns deep, transferable structure, not a parrot that matches shallow patterns. Real generalization would unblock many today’s key open problems: data-efficient (online) learning, shortcut learning, transfer capabilities from verifiable domains (math, coding) to broader non-verifiable yet economically valuable domains, and maintain a coherent character that truly aligns with human values.

The distinction between parrots and intelligence is computational. Parrots repeat in-context patterns; intelligence infers in-context functions. Parrots encode a persona as bags of disconnected facts and traits; intelligence learns a shared persona representation that connects all. Parrots memorize reasoning steps; intelligence forms general reasoning circuits for entity tracking, backtracking, or even for highly abstract concepts like truth.

AI-generated fake citations are flooding scientific literature across publications, scientists warn

The citations at the end of a research paper should represent a solid foundation of existing knowledge about a particular field, a pool of peer-reviewed sources built over years of research and study. However, with the increasing use of AI and large language models in writing research papers, there’s a growing chance that the citation someone clicks on may not even exist, and that the study, the source, or even the researchers themselves could be entirely fake.

In a recent study posted to the arXiv preprint server, researchers audited millions of papers and found that an estimated 146,900 hallucinated citations were present in research papers hosted on four major scientific repositories— arXiv, bioRxiv, SSRN, and PubMed Central. These numbers were for 2025 alone.

The hallucinated citations were not limited to a handful of bad apples but appeared across many papers, each containing a small number of fake references, pointing to a broader pattern of researchers using AI yet failing to fact-check the output.

How looking through static can help people with a common degenerative disease see better

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness among aging people globally. Around one in seven Australians over the age of 50 have some signs of AMD.

The disease results in blurred and distorted vision, and often loss of function at the center of the eye’s visual field.

The best current treatment involves a series of injections to slow the progression of the disease, but this process can be expensive and difficult with potentially negative long-term effects.

Stanford CS231N Deep Learning for Computer Vision I 2025

Computer Vision has become ubiquitous in our society, with applications in search, image understanding, apps, mapping, medicine, drones, and self-driving cars. Core to many of these applications are visual recognition tasks such as image classification, localization and detection. Recent developments in neural network (aka “deep learning”) approaches have greatly advanced the performance of these state-of-the-art visual recognition systems. This course is a deep dive into deep learning methods with a focus on end-to-end models for core vision tasks, alongside modern approaches such as transformers, diffusion models, and visual-language models that power today’s AI systems. During the 10-week course, students will learn to implement and train their own neural networks and gain a detailed understanding of cutting-edge research in computer vision. Additionally, the final assignment will give them the opportunity to train and apply multi-million parameter networks on real-world vision problems of their choice. Through multiple hands-on assignments and the final course project, students will acquire the toolset for setting up deep learning tasks and practical engineering tricks for training and fine-tuning deep neural networks. https://online.stanford.edu/courses/cs231n-deep-learning-computer-vision

Battery-free skin-conformal wearable system can measure electrocardiogram signals

A research team led by Prof. Jerald Yoo from the Department of Electrical and Computer Engineering at Seoul National University (SNU) has developed a skin-conformal wearable health care system, “SkinECG,” capable of measuring electrocardiogram (ECG) signals without a battery. By combining energy harvesting with human body–coupled power transfer, the study presents a new solution to one of the most critical challenges in wearable devices: power supply.

The findings are published in Science Advances.

Wearable health care systems are emerging as next-generation medical technologies that enable real-time monitoring of physiological signals through body-worn sensors, allowing early detection of disease-related abnormalities.

Jacob Barandes — “A New Formulation of Quantum Theory”

Talk by Jacob Barandes (Harvard University)
Seminar Website: https://harvardfop.jacobbarandes.com/
YouTube Channel: / @foundationsofphysicsharvard.
Foundations of Physics @Harvard Seminar Series.
April 12, 2023.

Abstract: In this talk, I will present a novel, exact correspondence between stochastic-process theory and quantum theory. On the one hand, this stochastic-quantum correspondence means that one can use the Hilbert-space tools of quantum theory to model real-world stochastic processes beyond the usual Markov approximation, generalizing previous stochastic approaches to quantum theory as well as potentially opening up new applications for quantum simulators and quantum computers. On the other hand, the stochastic-quantum correspondence implies that one can replace the instrumentalist textbook axioms of quantum theory with much more physically transparent axioms. The result is a clearer physical picture underlying quantum theory that is consistent with the standard no-go theorems, helps clarify the meaning of signature features of quantum theory like interference and entanglement, and has potential implications for addressing the measurement problem.

Small Study Shows One-time Cell Therapy Can Control HIV Infection

Unlike previous HIV “cures” involving cancer patients given bone marrow stem cells from a donor with a rare genetic mutation that resists HIV infection, researchers said CAR-T could be used by a much broader patient population. The Phase 1 trial involved CAR-T, a one-time therapy in which a patient’s T-cells are extracted, altered and multiplied in a lab and infused back into ⁠their body. In this case, the CAR-T targeted the CD4 and CCR5 binding sites of the HIV.

Of three trial patients ‌treated with a standard CAR-T dose, researchers said two maintained undetectable to ‌very low levels of HIV after stopping antiretroviral therapy — one for over two years so far and another for nearly a year. “The two that have ‌been off (HIV drugs) the longest and doing well were importantly diagnosed pretty quickly and put on therapy pretty quickly,” said Dr. Steven Deeks, professor of medicine at the University of California, San Francisco and the study’s lead investigator.

Currently, CAR-T ‌treatments are available for several types of blood cancer, and are being developed for autoimmune diseases like lupus and scleroderma. Tap the link to learn more about the recent study.


Re-engineering an HIV patient’s own immune cells to find and destroy the virus succeeded in controlling the infection in a small first-in-human study, but researchers said work is needed to confirm ⁠the findings and determine which patients are most likely to benefit.

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