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This is how the Economic Singularity becomes real. đŸ€–

“Employees of the General Services Administration, which manages government real estate and certain IT efforts, have been given a custom chatbot from Elon Musk’s DOGE to help automate tasks, according to a new report from Wired, with an internal memo telling workers it can be used to ” draft emails, create talking points, summarize text, write code.”

The GSA is one of the many agencies that have been affected by the federal government’s mass job cuts, and has so far let go upwards of 1,000 workers



According to a report from Wired, DOGE’s ‘GSAi’ chatbot is now in the hands of about 1,500 General Services Administration workers.

Laura Trachsel-Moncho, Anne Simonsen and colleagues (Universitetet i Oslo (UiO)) identify the endosomal protein SNX10 as a modulator of piecemeal mitophagy of OXPHOS machinery components and mitochondrial homeostasis. They show that loss of SNX10 enhances mitochondrial protein degradation, reduces respiration, and increases ROS levels, leading to elevated cell death in vivo.


Trachsel-Moncho et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Quantum computing has long struggled with creating entangled photons efficiently, but a team of researchers has discovered a game-changing method using metasurfaces—flat, engineered structures that control light.

By leveraging these metasurfaces, they can generate and manipulate entangled photons more easily and compactly than ever before. This breakthrough could open the door to smaller, more powerful quantum computers and even pave the way for quantum networks that deliver entangled photons to multiple users.

Revolutionizing Quantum Information Processing.

Scientists have identified the 1N4R tau isoform as a key driver of Alzheimer’s.

Alzheimer’s disease is a progressive neurological disorder that primarily affects older adults, leading to memory loss, cognitive decline, and behavioral changes. It is the most common cause of dementia. The disease is characterized by the buildup of amyloid plaques and tau tangles in the brain, which disrupt cell function and communication. There is currently no cure, and treatments focus on managing symptoms and improving quality of life.

NASA’s X-59 has cleared another hurdle with the successful completion of critical engine tests. The trials confirmed that its F414-GE-100 engine, adapted from the F-18 Super Hornet, performs as expected at full power. The aircraft’s design, including its unique top-mounted engine and elongated nose, aims to soften sonic booms to a mere “thump.” As NASA prepares for the first flight, additional tests will ensure the aircraft is ready for safe operation.

After an initial focus on scientific research, including Sierra’s partnership with Jeff Bezos’s Blue Origins on developing a private space station, the Dream Chaser will be involved in commercial operations by hauling cargo and shuttling scientists and researchers to and from space stations.

Both Sierra Space and Radian also have space-tourism aspirations that go beyond much of what’s currently available, including 11-minute flights by Virgin Galactic and Blue Origin, and longer space-balloon flights by companies like Space Perspective and Zephalto that do not reach Low Earth Orbit. “Passengers will be able to go up and stay in orbit,” says Humphrey, whose company has the most developed passenger plans right now. “We can go around the planet in about 95 minutes, so a typical trip will probably be three laps.”

Visits to one or more of the six space stations currently under development lie ahead as well. “We’re calling it purposeful tourism,” says Angie Wise, Sierra’s chief safety officer and SVP of mission and quality assurance. “You’ll get the experience of going to space, but we’ll also put you to work helping with experiments.”