Betelgeuse’s long-standing mystery has been cracked: a hidden companion star is literally reshaping the giant from the inside out.
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Scientists Tracked a Monster Solar Region for 94 Days. Here’s What They Discovered
Our sun spins on its axis about once every 28 days. Because of that, any active region can be watched from earth for only around two weeks before it turns out of view, then it stays hidden for roughly another two weeks on the far side.
“Fortunately, the Solar Orbiter mission, launched by the European Space Agency (ESA) in 2020, has broadened our perspective,” says Ioannis Kontogiannis, solar physicist at ETH Zurich and the Istituto ricerche solari Aldo e Cele Daccò (IRSOL) in Locarno.
Two Chrome Extensions Caught Stealing ChatGPT and DeepSeek Chats from 900,000 Users
Security researchers found two Chrome extensions with 900,000 installs secretly collecting ChatGPT and DeepSeek chats and browsing data.
Fake Booking Emails Redirect Hotel Staff to Fake BSoD Pages Delivering DCRat
A new PHALT#BLYX campaign targets European hotels using fake Booking.com emails, ClickFix lures, PowerShell, and MSBuild to deploy DCRat malware.
Kimwolf Android botnet abuses residential proxies to infect internal devices
The Kimwolf botnet, an Android variant of the Aisuru malware, has grown to more than two million hosts, most of them infected by exploiting vulnerabilities in residential proxy networks to target devices on internal networks.
Researchers observed increased activity for the malware since last August. Over the past month, Kimwolf has intensified its scanning of proxy networks, searching for devices with exposed Android Debug Bridge (ADB) services.
Common targets are Android-based TV boxes and streaming devices that allow unauthenticated access over ADB. Compromised devices are primarily used in distributed denial-of-service (DDoS) attacks, proxy resale, and monetizing app installations via third-party SDKs like Plainproxies Byteconnect.
How does the small molecule NVP-BHG712 protect against pulmonary fibrosis in mice?
Mohit Kapoor & team identify EphB4 receptor as a crucial mediator of pulmonary fibrosis that regulates genes involved in ECM organization, ER cargo concentration and protein trafficking in fibroblasts.
4Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.
5Department of Biostatistics, University Health Network, Toronto, Ontario, Canada.
6Dalla Lana School of Public Health and Department of Statistical Sciences, University of Toronto, Toronto, Ontario, Canada.
Antenatal melatonin for cardiovascular deficits in fetal growth restriction
Recent Research by Charmaine R. Rock of Hudson Institute of Medical Research et al. examines antenatal melatonin for cardiovascular deficits in fetal growth restriction 🫀 💊
🔗 📜 Read the study here.
The results of the present study indicate that melatonin has the potential to mitigate the progressive development of impaired endothelium-dependent vasodilatation in growth-restricted lambs. However, this benefit is associated with transient impairment of endothelial function on the first day of life. It would be prudent to investigate the physiological implications of this early vascular dysfunction during the critical period of cardiovascular adaptation to postnatal life. Adjustments to the antenatal melatonin treatment regime, such as tapering the dose before and after birth, could be explored to support a smoother cardiovascular transition on the first day of life.
Additionally, because the present study was conducted up to 4 weeks of age, equivalent to an ∼1-year-old human infant, extending the study outcomes into adulthood is important to determine whether endothelial function is sustained or continues to improve with age, potentially achieving full restoration to the relaxation abilities observed in control lambs. Furthermore, given that functional assessment of the carotid artery was not possible in our study, future research should include such testing to provide a more comprehensive understanding of how FGR impacts vascular function.
The present study provides novel insight into the short-and longer-term, and region-specific impact of melatonin on the cardiovascular system. Our findings demonstrate that, although antenatal melatonin improves the contribution of NO to endothelium-dependent vasodilatation in the femoral artery of newborn FGR+MLT lambs, it is accompanied by an overall reduction in femoral endothelium-dependent vasodilatory capacity. Notably, this reduction in endothelial function is transient and improves by 4 weeks of age, which contrasts with the progressive impairment of endothelial function seen in untreated FGR lambs. Immunohistochemical analysis revealed elevated oxidative stress and inflammatory markers in the femoral artery of 4-week-old FGR+MLT lambs.