I recorded this debate 14 years ago, and the question has only gotten sharper.
Lincoln Cannon is a software engineer with degrees in philosophy and business. He is also president of the Mormon Transhumanist Association. So when he argues that science and religion are complementary, he is not speaking from ignorance of either side.
I disagree with him. I think they are mutually exclusive. He thinks they complete each other.
So we sat down and argued it out. Friendly, but real.
This was a special edition of Singularity. FM, and it remains one of the more honest conversations I have had about belief, reason, and what transhumanism owes to both. The questions we wrestled with sit right at the heart of #transhumanism and the #futureofreligion in an age of accelerating #technology.
When a meteoroid strikes, it generates a wave of energy that moves faster than the speed of sound. When all that energy propagates through material in seconds or less before being quickly cooled and resolidified by a secondary wave, it produces glass.
Planetary Science Institute Senior Scientist Shawn Wright was looking for such glassy material while doing field work among the basaltic volcanic rock of Lonar crater in the Deccan region of India, when he found something unexpected.
“Some glassy samples were fluffy and light, like popcorn,” he said. “It had a really low density, it was airy, and it crumbled in my fingers. It looked different than all the other samples I’d seen and collected, so I aimed to find out what it was by trying to figure out what it used to be.”
When the magnitude 9.0 Tōhoku earthquake struck off the coast of Japan in 2011, its seismic shivers did more than ripple through the planet.
At least one wave traveled 2,900 kilometers (1,800 miles) down to the boundary between Earth’s mantle and liquid outer core, where it was reflected right back to the surface.
And there, according to a new analysis of earthquake data from across Japan, it may have done something scientists have never identified before.
I think this was one of my most enjoyable dialogues in our What’s new series. Maybe Sabine and I are getting more used to each other’s cadence and interests or maybe it was the subject matter. Either way, I think you will find this to be a fascinating and provocative discussion of science at the forefront, and at the not-so-forefront, because that science is interesting too! We began our discussion describing a new finding of a Giant Ring of galaxies billions of light years across in the sky. The key questions are: Is it real? And is it surprising? We both have slightly different takes on this. Next we described a new measurement of the strength of gravity on scales from 80 to 800 million light years in distance. And guess what? Gravity falls off just like Newton predicted! This may seem like a big yawn, but one of the most popular models that claims to do away with dark matter would imply that Gravity would fall off differently on these scales. Does this new result kill that idea? Stay tuned. Microsoft, which has cried wolf a number of times so far when it comes to something called Majorana qubits as the basis of a new viable quantum computer just published a new paper claiming they finally have it. Sabine and I discuss why we are both still skeptical, but why the effort is worth it. Next, CERN, the large European particle physics laboratory, and the world particle physics community seem to have converged on plans for building a huge new accelerator in the current CERN site… this time involving an underground ring 91 km in circumference, in which electrons and positrons would collide to explore the detailed properties of the Higgs particle. Is the effort worth it? Again, Sabine and I have slightly different takes on this. Fusion power, which we have talked about in a number of earlier episodes, continues to tempt humanity with the promise of unlimited energy. Many people, myself included, have tended to argue that fusion seems to be 25 years in the future, and may always be 25 years in the future. But many new efforts are underway, so who knows. Unfortunately, a group of economists has analyzed fusion in the context of other large energy programs and have argued that even if we can achieve it, it may not be as economically viable as many claim. Finally, one day Richard Feynman went to a Thai restaurant with his young companion Ralph Leighton, and wondered what he should order. Should it be the same old dish he loved or something new. An equation filled napkin later, and he had the answer. Fifty years later some cognitive scientists resurrected Feynman’s napkin and explained it, and argued it might have important implications in other social situations. Such is the power of science. Consider supporting the podcast and the Origins Project Foundation at https://www.originsproject.org/ To see commercial-free, full HD video episodes, join us at lawrence krauss.substack.com Thank you for your support! iTunes: https://podcasts.apple.com/us/podcast… https://TheOriginsPodcast.com Twitter: / theoriginspod Instagram: / theoriginspod Facebook: / theoriginspod The Origins Podcast, a production of The Origins Project Foundation, features in-depth conversations with some of the most interesting people in the world about the issues that impact all of us in the 21st century. Host, theoretical physicist, lecturer, and author, Lawrence M. Krauss, will be joined by guests from a wide range of fields, including science, the arts, and journalism. The topics discussed on The Origins Podcast reflect the full range of the human experience — exploring science and culture in a way that seeks to entertain, educate, and inspire. Full Episodes Playlist: • Ricky Gervais — The Origins Podcast with L…
The Path to Robust deAGI asks what it would take to build artificial general intelligence that is both powerful and structurally aligned with human flourishing—not just steered by after‑the‑fact safety patches. Ben Goertzel, CEO of SingularityNET and a founding member of the Artificial Superintelligence (ASI) Alliance, will outline how a decentralized, token‑coordinated ecosystem—combining ASI: Chain, Hyperon AGI, and community‑owned GPU clouds—can prevent AGI from being captured by any single corporation or state.
Goertzel will contrast centralized AGI roadmaps with a deAGI approach that bakes openness, diversity of values, and economic inclusion into the architecture itself, drawing on ideas like pluralistic training data, interoperable agent networks, and on‑chain governance of key system upgrades. He will also discuss technical milestones toward “robust” deAGI—modular cognitive architectures, decentralized marketplaces for AI services, and verification mechanisms that let communities audit and constrain AGI behavior—framing them as concrete steps toward an AGI that advances joy, growth, and choice for all rather than amplifying existing power imbalances.
Immunotherapies are a promising approach in the fight against cancer. Researchers at the Technical University of Munich (TUM) have developed a lab-on-a-chip system called CellTrap. It makes it possible to observe the interactions between immune cells and cancer cells at the single-cell level. The method is intended to reveal fundamental processes in cancer immunology and answer key questions. The technology is described in the journal RSC Advances.
Established laboratory tests mainly capture average values across many cells and show, for example, how many cancer cells survive after contact with immune cells. What happens in detail—how each cell reacts and interacts with others—remains hidden. However, to better understand the effectiveness of immunotherapies, the precise timing of a cell-cell interaction is often crucial: when contact, activation and, ultimately, the killing of the cancer cell occur.
Researchers in the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo have discovered a connection between a specific gene and healthy brain function. “The hope is that this discovery could eventually lead to expanded treatment for psychiatric and neurological disorders such as schizophrenia, bipolar disorder and autism,” explains Mikhail V. Pletnikov, MD, Ph.D., professor and chair of the Department of Physiology and Biophysics, the senior author of the study with Kateryna (Kate) Murlanova, Ph.D., the first lead author and a research scientist in the department.
They discovered that the NPAS3 gene expressed in astrocytes—the cells that help with brain chemistry—regulates the energy production required to support thinking and memory. NPAS3 is a transcription factor, which means it directs how certain genes work and influences how cells function. Their findings are published in Science Advances.
“Previous studies have linked NPAS3 to conditions involving cognitive problems, such as schizophrenia, but scientists didn’t know exactly how it might be involved,” Pletnikov says.
Background: Individuals with Down syndrome (DS) exhibit an almost complete penetrance of Alzheimer’s disease (AD) pathology but are underrepresented in clinical trials for AD. The Tau protein is associated with microtubule function in the neuron and is crucial for normal axonal transport. In several different neurodegenerative disorders, Tau misfolding leads to hyper-phosphorylation of Tau (p-Tau), which may seed pathology to bystander cells and spread. This review is focused on current findings regarding p-Tau and its potential to seed pathology as a “prion-like” spreader. It also considers the consequences of p-Tau pathology leading to AD, particularly in individuals with Down syndrome. Methods: Scopus (SC) and PubMed (PM) were searched in English using keywords “tau AND seeding AND brain AND down syndrome”
A new gene therapy has been used to successfully treat a deadly childhood liver disease in mice that model the disease, according to researchers at UCL and Great Ormond Street Hospital. Arthrogryposis, renal dysfunction and cholestasis (ARC) syndrome is a lethal genetic disorder usually caused by a lack of the VPS33B protein, with children diagnosed with the condition rarely living beyond their first year of life.
Now, in a study published in Nature Communications, the UCL-GOSH team found that by injecting a healthy version of the gene into the body, they can treat the condition in mice lacking VPS33B. Crucially, the final version of the treatment, which specifically targeted the liver cells, caused no harm. In the earlier versions, the genes became abnormally activated and caused cancerous cells to grow and expand in some cases.
While more tests must be done before the treatment can be tested in humans, the researchers’ breakthrough offers hope to babies with this devastating disorder and their families. In the UK, as many as six pregnancies per year might be affected by ARC syndrome. Furthermore, the findings may promote improved understanding of why some treatments may cause cancer.
