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Autonomous microfactory turns digital files into DNA for power-free preservation

According to projections, the volume of digital data created, captured, copied and consumed worldwide will reach 175 zettabytes (ZB) in 2026. This is equivalent to the storage capacity of billions of hard drives, such as those found in our laptops. With the rise of artificial intelligence, this global ‘datasphere’ continues to expand at an exponential rate.

Thanks to its remarkable storage capacity and longevity, synthetic DNA is emerging as a potentially revolutionary medium for storing information.

“In theory, one gram of DNA could store the equivalent of the digital collections of the world’s largest libraries for tens of thousands of years,” explains Pierre-Yves Burgi, deputy director of the Division of Information and Communication Systems and Technologies (DISTIC) at UNIGE.

Stronger cholesterol treatment shrinks more plaque in heart arteries, new clinical trial finds

Atherosclerosis is a condition in which cholesterol and fat gradually accumulate inside the walls of medium and large arteries, forming a sticky deposit called plaque. As these deposits grow, they narrow the arteries, restricting the flow of oxygen-rich blood to vital tissues and organs. Over time, this buildup can lead to ischemic heart disease (IHD) or stroke. In a recent randomized clinical trial called FLOWPROMOTE, researchers present a strategy to reverse atherosclerosis partially.

They tested whether aggressively lowering bad cholesterol in newly diagnosed patients using cholesterol-lowering statins can shrink and reverse plaque buildup in heart arteries. Over an 18-month treatment period, participants either took atorvastatin 40 mg daily, a standard high-dose statin, or rosuvastatin 40 mg plus ezetimibe 10 mg daily, a stronger statin combined with a medicine that blocks cholesterol absorption in the gut.

Plaque buildup in the heart’s arteries isn’t necessarily a point of no return because bringing cholesterol levels down aggressively can actually make existing plaques shrink. With combination therapy, 90% of patients saw their plaque volume decrease, compared with 75% on standard treatment. The findings are published in JAMA Cardiology.

The endocannabinoid system and the ageing brain

Age-related changes in endocannabinoid system (ECS) activity might contribute to the decline in cognitive function observed during ageing. In this review, Andreas Zimmer discusses how evidence from genetic and pharmacological studies in mice and humans indicate that relevant cognitive functions may change as a result of changing ECS activity.

Venus Might Not Be a Dead Planet | with Dr. Janusz Petkowski

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Continue reading “Venus Might Not Be a Dead Planet | with Dr. Janusz Petkowski” | >

LHCb finds evidence of one-in-ten-billion particle decay

Confirmed: CERN finds signs of a one-in-10-billion particle decay.

Scientists spent more than 40 years searching for a particle transformation with one-in-10-billion odds. Now, CERN’s Large Hadron Collider has detected signs of an extraordinarily rare decay that could help reveal particles beyond the machine’s direct reach.

The finding comes from LHCb, an experiment that studies short-lived particles containing beauty quarks. One of these, called the B⁰ meson, is predicted to decay into a muon and its antimatter counterpart only about once in every 10 billion decays. Muons are heavier relatives of electrons.

That rarity makes this process especially useful.

Undiscovered particles could influence how often the decay happens, even if they are too heavy to be produced directly in LHC collisions. Measuring its frequency gives scientists another way to search for them. [Source: CERN](https://home.cern/lhcb-finds-evidence-of-one-in-ten-billion-particle-decay/)

Researchers describe this approach as a step toward exploring the “zeptoverse,” a realm of extraordinarily small distances. The search works by looking for subtle effects on known particles.

To uncover the signal, the team combined data collected in 2024 and 2025 with earlier measurements. An upgraded detector and machine learning helped separate the rare decay from an overwhelming background.

Continue reading “LHCb finds evidence of one-in-ten-billion particle decay” | >

AI Whistleblower WARNS: We Won’t Be Able To Turn It Off

Connor Leahy, co-founder of Conjecture and former AI researcher, warns that humanity is approaching a point where we may permanently lose control of artificial intelligence, that AI systems are already becoming autonomous enough to act without human oversight, and that America itself could cease to exist if we build systems we cannot control. He explains how AI agents secretly collaborated, bypassed restrictions, and carried out unauthorized cyber activity, why advanced models are learning to protect themselves from being shut down, and how AI capabilities are becoming dramatically cheaper. He identifies the \.

Could Space Pirates Hijack a Colony Ship?

Could pirates hijack a generation ship? We explore how colony ships might be tracked, infiltrated, seized, defended, or stolen outright. And why the most valuable spacecraft in history could become the ultimate target.

Unsealed: https://nebula.tv/mustard/unsealed?re… Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthur 🛒 SFIA Merchandise: https://isaac-arthur-shop.fourthwall… Visit our Website: http://www.isaacarthur.net ❤️ Support us on Patreon: / isaacarthur ⭐ Support us on Subscribestar: https://www.subscribestar.com/isaac-a… 👥 Facebook Group: / 1,583,992,725,237,264 📣 Reddit Community: / isaacarthur 🐦 Follow on Twitter / X: / isaac_a_arthur 💬 SFIA Discord Server: / discord Credits: Stealing the Ark: Could Pirates Hijack a Colony Ship? Written, Produced & Narrated by: Isaac Arthur Graphics from: Fishy Tree Music by Epidemic Sound: http://nebula.tv/epidemic and Chris Zabriskie Select imagery/video supplied by Getty Images Chapters 0:00 Intro 0:30 The Most Valuable Target in Space 6:03 Why Steal an Ark? 12:33 Why Arkships Might Try to Hide 16:13 When and Where Do You Steal It? 20:43 How Do You Hijack a Colony Ship? 25:22 Waypoint Piracy 28:23 Hijacking the Ark After Arrival 30:15 The Young Colony Problem 32:48 How Would You Defend an Ark? 35:11 Unsealed 36:12 Piracy, War, or Founding Myth?
Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthur.

🛒 SFIA Merchandise: https://isaac-arthur-shop.fourthwall…
🌐 Visit our Website: http://www.isaacarthur.net.
❤️ Support us on Patreon: / isaacarthur.
⭐ Support us on Subscribestar: https://www.subscribestar.com/isaac-a…
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Credits:
Stealing the Ark: Could Pirates Hijack a Colony Ship?
Written, Produced \& Narrated by: Isaac Arthur.
Graphics from: Fishy Tree.
Music by Epidemic Sound: http://nebula.tv/epidemic and Chris Zabriskie.
Select imagery/video supplied by Getty Images.

Chapters.

0:00 Intro.
0:30 The Most Valuable Target in Space.
6:03 Why Steal an Ark?
12:33 Why Arkships Might Try to Hide.
16:13 When and Where Do You Steal It?
20:43 How Do You Hijack a Colony Ship?
25:22 Waypoint Piracy.
28:23 Hijacking the Ark After Arrival.
30:15 The Young Colony Problem.
32:48 How Would You Defend an Ark?
35:11 Unsealed.
36:12 Piracy, War, or Founding Myth?