Lifeboat Foundation

NUS researchers found that deuterated water (D₂O) reduces pain by modulating the TRPV1 ion channel, offering a non-addictive alternative to conventional painkillers.

Researchers from the National University of Singapore (NUS), in partnership with Peking University, China, have uncovered new insights into the TRPV1 (transient receptor potential vanilloid 1) ion channel and its role in pain perception. Their findings demonstrate how solvent molecules can influence pain signals, paving the way for potential development of safer, non-addictive pain management strategies.

Effective pain management is vital for improving quality of life and overall well-being. The TRPV1 ion channel, which plays a key role in detecting pain, expands its pore when activated, enabling ions and larger molecules to pass through. However, the ability of water molecules to permeate the TRPV1 channel has remained uncertain.

Scientists predict an undersea volcano will erupt in 2025, the volcano has been dubbed ‘the most well-instrumented submarine volcano’ on the planet and activity is imminent.

As tech companies release a slew of generative AI updates, there’s a growing risk that educational practices and policies are struggling to keep up with new capabilities.

For the past 30 years, NASA’s Great Observatories—the Hubble, Spitzer, Compton, and Chandra space telescopes—have revealed some amazing things about the universe. In addition to some of the deepest views of the universe provided by the Hubble Deep Fields campaign, these telescopes have provided insight into the unseen parts of the cosmos—i.e., in the infrared, gamma-ray, and ultraviolet spectrums.

With the success of these observatories and the James Webb Space Telescope (JWST), NASA is contemplating future missions that would reveal even more of the “unseen universe.”

This includes the UltraViolet Explorer (UVEX), a space telescope NASA plans to launch in 2030 as its next Astrophysics Medium-Class Explorer mission. In a recent study, a team led by researchers from the University of Michigan proposed another concept known as the Mission to Analyze the UltraViolet universE (MAUVE). This telescope and its sophisticated instruments were conceived during the inaugural NASA Astrophysics Mission Design School. According to the team’s paper, this mission would hypothetically be ready for launch by 2031.

The glymphatic system becomes more active during sleep, especially during deep sleep, allowing for more effective waste clearance, said psychiatrist Dr. Jingduan Yang, founder of the Yang Institute of Integrative Medicine in Pennsylvania.

In a mouse study published in Science, researchers used tracers to monitor changes in cerebrospinal fluid flow. They found that during sleep, the interstitial, or intervening, space expanded by more than 60 percent, and the tracer influx increased. The brain’s clearance rate of beta-amyloid doubled during sleep (or under anesthesia) compared to the awake state.

Summary: This article explores how humanity has advanced its knowledge of biodiversity over time, from folk wisdom to modern databases. It highlights how technology has made information about life on Earth accessible to everyone and argues we should be optimistic about the future of taxonomy and conservation.

Alone in the forest, the modern person might find it difficult to identify a beech tree. Compared to indigenous shamans who forage thousands of medicinal plants, we are deeply disconnected from nature. But even if our personal understanding of nature is in decline, as a species, we’ve never known more about the natural world.

The fact is, while it is valuable, indigenous knowledge is often limited to the local area, difficult to distinguish from myth and ritual, and, if passed on orally, easy to lose. Literate naturalists faced similar problems. Aristotle recorded many species in writing, but much of his work was lost. Most traditional written research that survived to modern times is narrow in scope, disorganized, and spread throughout obscure tomes.

Sit all day at the office? You might want to rethink that. Long hours in the chair are bad for your health. WebMD explains why it’s time to get up and stretch your legs.

Fasting in office or starving yourself at work might be a health time bomb. Here’s how to stop it to avoid the risk of heart disease and keep it beating strong.

The vast gulfs between stars may take decades or even centuries to travel, requiring enormous generation ships carrying families and whole ecosystems with them. What will life be like on board such arks?

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