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Rising early-onset cancer diagnoses in the US appear to be driven by increased detection, not disease

Harvard Medical School, Brigham and Women’s Hospital, and Dell Medical School researchers report that rising rates of early-onset cancer in the United States may reflect more diagnoses rather than more disease.

Cancer awareness and prevention have intensified over many decades, removing potential environmental risk factors from daily life. Mortality of all cancers combined in adults under 50 has decreased by nearly half since the 1990s.

Still, public concern has climbed amidst rising diagnoses and high-profile early-onset cases. PubMed citations related to early-onset cancer more than tripled and screening ages have been shifted down to 45 for and 40 for breast cancer. Uncertainty persists about whether the higher case counts signal greater cancer occurrence or more frequent detection.

Heat-rechargeable computation in DNA logic circuits and neural networks

Heat recharges enzyme-free DNA circuits, enabling complex logic operations and neural networks to perform multiple computations, offering a universal energy source for molecular machines and advancing autonomous behaviours in artificial chemical systems.

Six billion tons a second: Rogue planet found growing at record rate

Astronomers have identified an enormous “growth spurt” in a so-called rogue planet. Unlike the planets in our solar system, these objects do not orbit stars, free-floating on their own instead. The new observations, made with the European Southern Observatory’s Very Large Telescope (ESO’s VLT), reveal that this free-floating planet is eating up gas and dust from its surroundings at a rate of six billion tons a second. This is the strongest growth rate ever recorded for a rogue planet, or a planet of any kind, providing valuable insights into how they form and grow.

300,000-year-old genomes: History of the Schöningen horses deciphered

For the first time, a research team from the Senckenberg Center for Human Evolution and Paleoenvironment at the University of Tübingen and the Schöningen Research Center have reconstructed the genomes of an extinct horse species, Equus mosbachensis, from the archaeological site of Schöningen in Lower Saxony, which is approximately 300,000 years old.

Thanks to exceptionally favorable preservation conditions, the researchers were able to identify the oldest DNA yet discovered from an open-air site. Their analyses show that the Schöningen horses belong to a lineage that is considered to be the origin of all modern horses. The study is published in the journal Nature Ecology & Evolution.

Domestic and , donkeys and zebras all belong to the sole genus of the family Equidae still in existence today. But a look into the shows that more than 35 different genera and hundreds of now extinct equine species occurred throughout the past.

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