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A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology

This multicenter study demonstrates use of dried and capillary blood as a minimally invasive, scalable approach for Alzheimer’s biomarker testing in research, with potential as a widely scalable population-based research approach, especially in resource-limited settings.

Sulfate and carbon in fine air pollution tied to higher depression risk

Long-term exposure to fine particulate matter like PM2.5 components in polluted air can not only cause respiratory diseases, but also increase the risk of depression in older people, especially in those living with preexisting heart, metabolic and neurological conditions.

Depression has caused more loss of healthy life worldwide than any other mental health condition. This disorder has snatched away people’s will to perform the basics of daily activities. An analysis of global health data in 2021 showed that all the years people lived with disability or reduced quality of life because of depression added up to about 56.3 million years.

A recent population-based cohort study collected data from nearly 23.7 million U.S. Medicare beneficiaries aged 65 years and older between 2000 and 2018 to examine specific components of PM2.5 exposure, both individually and in combination, and its associations with the risk of developing depression. Among those tracked, more than 5.5 million developed depression during the follow-up period. These findings are published in JAMA Network Open.

3D imaging uncovers mosquito’s specialized neurons for detecting carbon dioxide

It’s bound to happen at a summer picnic, a peaceful walk in the woods or simply sitting in your backyard… a mosquito targets your blood for its next meal. You’ve been bitten. But how do mosquitoes find you?

Among several methods used to locate new hosts for blood-sucking, mosquitoes feature a keen ability to detect . As we breathe out, we emit CO2 into the air around us, which mosquitoes can sense. But how?

Scientists have been aware of the mosquito’s ability to detect our carbon dioxide expirations but the intricate underlying physiological structures enabling these capabilities have largely remained unclear.

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