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Dementia has many faces, and because of the wide range of ways in which it can develop and affect patients, it can be very challenging to treat. Now, however, using supercomputer analysis of big data, researchers from Japan were able to predict that a single protein is a key factor in the damage caused by two very common forms of dementia.

In a study published this month in Communications Biology, researchers from Tokyo Medical and Dental University (TMDU) have revealed that the protein HMGB1 is a key player in both frontotemporal lobar degeneration and Alzheimer disease, two of the most common causes of dementia.

Frontotemporal lobar degeneration can be caused by mutation of a variety of genes, which means that no one treatment will be right for all patients. However, there are some similarities between frontotemporal lobar degeneration and Alzheimer disease, which led the researchers at Tokyo Medical and Dental University (TMDU) to explore whether these two conditions cause damage to the brain in the same way.

Is there something special about consciousness? Can our inner subjective experience—the sight of purple, smell of cheese, sound of Bach—ever be explained in purely physical terms? Even in principle? Most scientists see consciousness as a science problem to solve. Some philosophers claim that consciousness can never be explained in terms of current science.

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Summary: A new technique dubbed light beads microscopy allowed researchers to generate a vivid functional movie of the near-simultaneous activity of almost a million neurons in the mouse brain.

Source: Rockefeller University.

Capturing the intricacies of the brain’s activity demands resolution, scale, and speed—the ability to visualize millions of neurons with crystal clear resolution as they actively call out from distant corners of the cortex, within a fraction of a second of one another.

Cognitive biases have been studied for decades by academics in the fields of cognitive science, social psychology, and behavioural economics.

View the high resolution version of today’s graphic by clicking here.

The human brain is capable of incredible things, but it’s also extremely flawed at times.

Continue reading “Visualising every single cognitive bias” »

Citicoline, a drug that is naturally found in the body, is commonly used to treat a number of brain injuries and illnesses. For quite some time, doctors have prescribed it for strokes, vascular dementia, Parkinson’s disease, and general aging of the brain. Patients usually see improvement when taking the drug because the body uses it to create and repair cell membranes and lower the presence of free radicals, as noted in the Clinical Interventions in Aging Journal. (Free radicals, which are unstable molecules, can damage cells in the body and are associated with aging and illness.)

Now, researchers from the NYU Grossman School of Medicine have found evidence that citicoline can also be used to treat glaucoma. Normally, glaucoma is treated by removing fluid buildup in the eye, which creates pressure and wears down the cells in the eye and the nerves connecting to the brain. Though monitoring fluid buildup is important, glaucoma can still worsen after the pressure on the eye has been relieved.

Because the herpesvirus sits in neurons forever, there is speculation it is connected to neurodegenerative diseases. The immune system requires inflammation to constantly fight off the virus, and neurons have some degree of damage because of this continuous immune response, according to Dr. Tibor Valyi-Nagy, professor of pathology, director of neuropathology at UIC and research collaborator on the study.

Summary: Researchers discovered mutations of the OPTN gene resulted in increased herpesvirus 1 growth in the brains of mice, leading to the death of local neurons. This resulted in accelerated neurodegeneration. OPTN deficiency was also associated with impairments in immune response. While these findings are specific to the HSV-1 virus, researchers believe the findings may apply to up to eight herpesvirus infections.

Source: University of Illinois at Chicago

Continue reading “Study Finds Evidence of Possible Link Between Herpes Simplex and Neurogenerative Diseases” »

Britain’s young teens will be vaccinated — but with a single dose.

London: Britain’s chief medical officers have said that vaccinating young teenagers against COVID-19 is justified when their mental health and education are taken into account.

Minors aged between 12 and 15 in England will be offered just a single dose of Pfizer or Moderna beginning next week, with more research ordered into whether a second dose should be given, as is currently administered to those aged 16 and above.

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Anna’s guest at Women’s Radio was Dr Ian C E Hale I’m an Autistic person. It’s an indivisible part of who I am as an individual.

Annas guest at Women’s Radio was Dr Ian C E Hale ‘All things Autism will be aired at 1pm and 1am every day this week. Please see www.womensradiostation.com

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My guest tomorrow on Womens Radio Station at 1pm is Dr Ian Hale. Author of ‘Asperger’s Autism & You’

www.womensradiostation.com

Hale, Ian] on Amazon.com. *FREE* shipping on qualifying offers. Asperger’s, Autism & You.

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