H5N5 was only reported in non-human animals – until now.
Category: biotech/medical – Page 41
This 250-Year-Old Whale Might Hold the Key to Human Longevity
Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/
Timestamps:
00:00 Intro.
00:41 DNA damage and aging.
01:37 Why bowhead whales live so long.
03:13 Cold shock proteins and lifespan.
04:43 Body temperature and longevity.
06:50 Acute cold exposure benefits.
08:10 Takeaway.
100 Health Biomarkers Ranked: https://youtu.be/SgKp5mm0ALI?si=M7YkYo6Lelci7kOQ
Start rewinding your biological clock: https://www.siimland.co/course.
P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.
DNA polymerase β suppresses somatic indels at CpG dinucleotides in developing cortical neurons
New research finds that dying cells leave a “footprint of death” that guides immune responses — but viruses like influenza can exploit this signaling. The discovery, published in Nature Communications, offers new insight into cell death, viral transmission, and potential drug targets.
New insights into the aftermath of cell death might ultimately inform drug development.
Single-celled organisms have more complex DNA epigenetic code than multicellular life, researchers discover
Multicellular organisms (animals, plants, humans) all have the ability to methylate the cytosine base in their DNA. This process, a type of epigenetic modification, plays an important role in conditions such as cancer and processes such as aging.
In a paper appearing in Nature Genetics, researchers discover that in more “primitive” unicellular organisms, both the adenine and the cytosine bases are methylated. This would suggest that in some ways, these unicellular organisms are more complex than their multicellular peers.
The team also found that methylation of the adenine base was, in the case of many of these unicellular organisms, vital for controlling which genes are switched on, which is important for their viability.
The ‘Great Unified Microscope’ can see both micro and nanoscale structures
Researchers at the University of Tokyo have built a microscope that can detect a signal over an intensity range 14 times wider than conventional microscopes. Moreover, the observations are made label-free, that is, without the use of additional dyes.
This means the method is gentle on cells and adequate for long-term observations, holding potential for testing and quality control applications in the pharmaceutical and biotechnology industries. The findings are published in the journal Nature Communications.
Microscopes have played a pivotal role in the development of science since the 16th century. However, progress has required not only more sensitive and accurate equipment and analysis, but also more specialized ones. Therefore, modern, cutting-edge techniques have had to straddle trade-offs.
Root canal treatment could significantly lower blood sugar levels, study suggests
“Our oral health is connected to our general health,” said Dr Sadia Niazi, a senior clinical lecturer in endodontology at King’s College London. “We should never look at our teeth or dental disease as a separate entity.”
Root canal treatment is one of the most common – and perhaps most feared – dental procedures, though much of the anxiety derives from myths and misconceptions that hark back to the days of poor anaesthetics. The treatment is performed to treat infection or damage to the tooth’s pulp, the soft inner tissue of a tooth that contains nerves, blood vessels and connective tissue.
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If a looming root canal treatment is putting a dampener on the week, take heart: having the procedure can drive health benefits that are felt throughout the body, according to research.
Patients who were successfully treated for root canal infections saw their blood sugar levels fall significantly over two years, suggesting that ridding the body of the problematic bacteria could help protect against type 2 diabetes.
Dentists also saw improvements in patients’ blood cholesterol and fatty acid levels, both of which are associated with heart health. Yet more benefits were seen around inflammation, a driver for cardiovascular disease and other chronic conditions.
A Common Diabetes Drug Is Linked to ‘Exceptional Longevity’ in Women
Not only can the drug metformin help to effectively manage type 2 diabetes, but it may also give older women a better chance of living to the grand old age of 90, according to recent research – thanks, it seems, to a variety of anti-aging effects.
Scientists in the US and Germany used data from a long-term US study of postmenopausal women. Records on a total of 438 people were picked out – half of whom took metformin to treat diabetes, and half who took a different diabetes drug, called sulfonylurea.
While there are some caveats and asterisks to the study, those in the metformin group were calculated to have a 30 percent lower risk of dying before the age of 90 than those in the sulfonylurea group.
From artificial organs to advanced batteries: A breakthrough 3D-printable polymer
A new type of 3D-printable material that gets along with the body’s immune system, pioneered by a University of Virginia research team, could lead to safer medical technology for organ transplants and drug delivery systems. It could also improve battery technologies.
The breakthrough is the subject of a new article published in the journal Advanced Materials, based on work done by the University of Virginia’s Soft Biomatter Laboratory, led by Liheng Cai, an associate professor of materials science and engineering and chemical engineering. The paper’s first author is Baiqiang Huang, a Ph.D. student in the School of Engineering and Applied Science.
Their research shows a way to change the properties of polyethylene glycol to make stretchable networks. PEG, as it’s known, is a material already used in many biomedical technologies such as tissue engineering, but the way PEG networks are currently produced—created in water by crosslinking linear PEG polymers, with the water removed afterward—leaves a brittle, crystallized structure that can’t stretch without losing its integrity.
UT Eclipses 5,000 GPUs To Increase Dominance in Open-Source AI, Strengthen Nation’s Computing Power
Amid the private sector’s race to lead artificial intelligence innovation, The University of Texas at Austin has strengthened its lead in academic computing power and dominance in computing power for public, open-source AI. UT has acquired high-performance Dell PowerEdge servers and NVIDIA AI infrastructure powered by more than 4,000 NVIDIA Blackwell architecture graphic processing units (GPUs), the most powerful GPUs in production to date.
The new infrastructure is a game-changer for the University, expanding its research and development capabilities in agentic and generative AI while opening the door to more society-changing discoveries that support America’s technological dominance. The NVIDIA GB200 systems and NVIDIA Vera CPU servers will be installed as part of Horizon, the largest academic supercomputer in the nation, which goes online next year at UT’s Texas Advanced Computing Center (TACC). The National Science Foundation (NSF) is funding Horizon through its Leadership Class Computing Facility program to revolutionize U.S. computational research.
UT has the most AI computing power in academia. In total, the University has amassed more than 5,000 advanced NVIDIA GPUs across its academic and research facilities. The University has the computing power to produce open-source large language models — which power most modern AI applications — that rival any other public institution. Open-source computing is nonproprietary and serves as the backbone for publicly driven research. Unlike private sector models, it can be fine-tuned to support research in the public interest, producing discoveries that offer profound benefits to society in such areas as health care, drug development, materials and national security.
