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‘Turbocharged’ Mitochondria Power Birds’ Epic Migratory Journeys

Scientists have long been fascinated with the physiological changes that birds undergo before and during migration. Some birds eat so much fat before their journeys that they double in body weight. In some species, their hearts are enlarged to pump more blood, or their digestive tracts grow and then shrink. But researchers have only recently started to explore at a fundamental level how migratory birds get the energy required to keep themselves aloft for days on end without eating.

Last year, two independent groups published research that explored migratory bird physiology in the lab and field to probe what happens at the subcellular level that allows birds to cover vast distances. They both found answers in biology’s most fundamental engine: mitochondria.

Their studies show how small changes in the number, shape, efficiency and interconnectedness of mitochondria can have huge physiological consequences that contribute to birds’ long-duration, continent-spanning flights.

UNM Scientists Discover How Nanoparticles of Toxic Metal Used in MRI Scans Infiltrate Human Tissue

University of New Mexico researchers studying the health risks posed by gadolinium, a toxic rare earth metal used in MRI scans, have found that oxalic acid, a molecule found in many foods, can generate nanoparticles of the metal in human tissues.

ISensor and iMedicine for Human Health

Diabetes has no well-established cure; thus, its management is critical for avoiding severe health complications involving multiple organs. This requires frequent glycaemia monitoring, and the gold standards for this are fingerstick tests. During the last decades, several blood-withdrawal-free platforms have been being studied to replace this test and to improve significantly the quality of life of people with diabetes (PWD). Devices estimating glycaemia level targeting blood or biofluids such as tears, saliva, breath and sweat, are gaining attention; however, most are not reliable, user-friendly and/or cheap. Given the complexity of the topic and the rise of diabetes, a careful analysis is essential to track scientific and industrial progresses in developing diabetes management systems. Here, we summarize the emerging blood glucose level (BGL) measurement methods and report some examples of devices which have been under development in the last decades, discussing the reasons for them not reaching the market or not being really non-invasive and continuous. After discussing more in depth the history of Raman spectroscopy-based researches and devices for BGL measurements, we will examine if this technique could have the potential for the development of a user-friendly, miniaturized, non-invasive and continuous blood glucose-monitoring device, which can operate reliably, without inter-patient variability, over sustained periods.

Diabetes is a lifelong disease that affects more than 400 millions of people worldwide (WHO. Diabetes, 2022). Emerging reports from the International Diabetes Federation state that diabetes is set to rise very fast, estimating 700 millions of cases in the next 25 years (IDF Diabetes Atlas, 2019). Among the various types of diabetes, all characterized by high blood glucose levels, the main two types are type 1 diabetes, an autoimmune condition where the pancreas produces little or no insulin, and type 2 diabetes, a metabolic disorder that results in hyperglycaemia due to insulin resistance. Diabetes, and related risk factors such as microvascular (retinopathy, nephropathy, and neuropathy) and macrovascular metabolic disorders, is so widespread that it has been defined “the epidemic of the century” (Kharroubi, 2015).

Scientists Messed Around With LSD and Invented a New Brain-Healing Drug

Researchers at UC Davis have fiddled with LSD at the atomic level and may have unlocked a potential game-changing treatment for schizophrenia. The new compound, known as JRT, might be able to repair the brain without making you trip balls.

The scientists, who posted their findings in the scientific journal Proceedings of the National Academy of Sciences, were toying with LSD atoms when they decided to, in their own words, do a “tire rotation.” This meant swapping the position of two atoms in LSD’s molecular structure.

That tiny change turned it from a powerful hallucinogen into something that can regrow brain cells in mice and mend neural pathways without launching your consciousness into the cosmos.

The Immortal Mind: How Neuroscience Points Beyond Materialism

Is your mind more than just your brain? Does the soul actually exist? These questions have been pondered for millennia. What does the latest scientific research suggest? On this episode of the ID The Future podcast, renowned neurosurgeon Dr. Michael Egnor begins a conversation with host @Andrew_McDiarmid about his new book The Immortal Mind: A Neurosurgeon’s Case for the Existence of the Soul. Egnor makes a powerful case that our capacity for thought, reason, and free will points to something beyond mere brain function.

After defining terms, Egnor begins exploring the compelling evidence he has gathered across four decades of practice in neurosurgery. He recounts the remarkable results of split-brain surgery, where patients whose brain hemispheres are functionally disconnected still feel like one person and can process information presented separately to each hemisphere. This implies a part of their mind is not solely located in their brain. You’ll also hear about conjoined twins who share brain parts but maintain distinct intellects and free will, highlighting which aspects of the soul are not brain-based and cannot be shared.

Along the way, Dr. Egnor also boldly challenges the Darwinian view of the mind’s evolution, arguing that abstract thought and free will are immaterial and could not have arisen through natural selection. Learn why Dr. Egnor believes nature is not a closed system and that science alone cannot fully interpret its own findings. Drawing on ancient philosophers like Aristotle and Thomas Aquinas, he presents arguments for a cause outside of nature.

This is Part 1 of a two-part interview. In Part 2, we’ll explore Dr. Egnor’s personal journey from atheism to theism and more evidence for the immortality of the mind and the existence of the soul.

Enjoy more ID The Future here:

#neuroscience #intelligentdesign #mind #brain.

Scientists uncover hundreds of unknown ocean species in historic expedition: ‘We are laying the groundwork’

Scientists have discovered 866 new marine species, including a guitar shark, a deep-sea mollusk with cancer treatment potential, and the first octocoral found in the Maldives, Oceanographic Magazine reported.

The Nippon Foundation-Nekton Ocean Census looks to change how scientists identify new marine species by speeding up the process. This discovery marks a “significant step” in advancing our understanding of ocean biodiversity. Traditional methods can take up to 14 years, but this international collaborative effort of 800 scientists from over 400 institutions is changing the approach.

Many species go extinct before they’re documented. The mission’s executive director explained that while oceans cover 71% of our planet, only about 10% of marine life has been discovered. By accelerating identification, scientists can better protect these species.

Amiloride found to be as effective as spironolactone in managing resistant hypertension

Yonsei University College of Medicine-led research has shown amiloride is as effective as spironolactone in reducing systolic blood pressure (SBP) over 12 weeks in patients with resistant hypertension.

Resistant affects approximately 10% of hypertensive patients and is associated with worse outcomes than nonresistant cases.

Spironolactone is a fourth-line medication, introduced only after renin-angiotensin system inhibitors, , and thiazide diuretics fail to control blood pressure. Adverse effects, particularly hyperkalemia and hormonal disruptions, limit its use in long-term care. Amiloride, a potassium-sparing diuretic, lacks these hormonal side effects, making it a potential replacement candidate.