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Category: biotech/medical – Page 39

Brain Abnormality in Modern Humans Linked to Ancient Neanderthal DNA

Significant brain defects known as Chiari malformations could be down the genes some of us have inherited from Neanderthals, according to a new study, causing a mismatch between brain shape and skull shape.

The study focuses on Chiari malformation type I (CM-I), where the lower part of the brain extends too far into the spinal cord – typically linked to having a smaller-than-normal occipital bone at the back of the skull. It can lead to headaches, neck pain, and more serious conditions, and is thought to affect up to 1 in 100 people.

Several other ancient human species had different skull shapes to our own, and a previous study published in 2013 put forward the idea that interbreeding between Homo sapiens and these other hominins may be a root cause of Chiari malformation type I (CM-I), the mildest type of the group.

Rethinking Inflammation: Is Everything We Know About Aging and Disease Wrong?

The environment strongly influences health outcomes, especially in industrialized societies. A new study from the Columbia University Mailman School of Public Health challenges the long-standing view that inflammation is a universal feature of aging. The research indicates that “inflammaging”—a p

LLNL researchers use AI to look for potential ALS treatments

Potential treatments for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases may already be out there in the form of drugs prescribed for other conditions. A team of researchers from Lawrence Livermore National Laboratory (LLNL), Stanford University and the University of California, Los Angeles (UCLA) are using artificial intelligence and machine learning (AI/ML) to try to find them.

Clinical trials for new drugs can take up to 5–7 years, so repurposing existing drugs is one of the best ways to deliver treatments quickly. AI/ML can make it even faster. By analyzing long-term electronic health records (EHRs) of patients with ALS, the team can identify drugs — or combinations of drugs — prescribed for other conditions that may influence the progression of the disease. The drugs’ “off-target” effects may not only affect patient survival but also provide insight into how neurodegenerative diseases work and inform better therapies.

“If you talk to any ALS caregiver, you will be moved because the disease has such a grim prognosis, so being able to do something is tremendously motivating,” said Priyadip Ray, a staff scientist in LLNL’s Computational Engineering Division (CED) who leads the effort.

The Dawn of Tesla’s Robotaxi Network & Automated Transportation

Tesla’s launch of a robo-taxi network marks the beginning of a significant transportation disruption that will transform mobility, economy, geopolitics, and urban landscapes with the widespread adoption of electric autonomous vehicles ## ## Questions to inspire discussion.

Transportation Revolution.

🚗 Q: How will Tesla’s Robotaxi network impact transportation? A: Tesla’s Robotaxi network in Austin, Texas marks the ignition point for transportation disruption, with multiple companies competing to provide taxi rides without human drivers, potentially capturing 80–90% market share in 10–15 years.

🛢️ Q: What industries will be disrupted by autonomous electric vehicles? A: Autonomous electric vehicles will disrupt the oil and agriculture industries, as vehicles are the number one users of crude oil, and corn is the top agricultural product in the US, used to produce ethanol for gasoline.

🌆 Q: How will urban planning change with the rise of autonomous vehicles? A: Cities will repurpose parking spaces for retail, living areas, and solar panels, transforming urban planning and enabling new forms of transportation, including drones and aircraft.

Environmental Impact.

Continue reading “The Dawn of Tesla’s Robotaxi Network & Automated Transportation” | >

Plasma proteomics links brain and immune system aging with healthspan and longevity

In a large-scale proteomic study of biological aging of 11 organs from 44,498 individuals in the UK Biobank, the biological ages of the brain and immune system emerged as strong predictors of healthspan and longevity.

Groundbreaking Biological “Artificial Intelligence” System Could Make Impossible Medicines Real

Australian researchers, including those at the Charles Perkins Centre at the University of Sydney

The University of Sydney is a public research university located in Sydney, New South Wales, Australia. Founded in 1850, it is the oldest university in Australia and is consistently ranked among the top universities in the world. The University of Sydney has a strong focus on research and offers a wide range of undergraduate and postgraduate programs across a variety of disciplines, including arts, business, engineering, law, medicine, and science.