Researchers have identified a key mechanism in the development of Alzheimer’s disease involving the growth and pause of amyloid β fibrils.
A newly discovered antibody can lock these fibrils in their paused state, offering a potential new approach for treatment that targets these critical growth points.
Nuclear fission—when the nucleus of an atom splits in two, releasing energy—may seem like a process that is fully understood. First discovered in 1939 and thoroughly studied ever since, fission is a constant factor in modern life, used in everything from nuclear medicine to power-generating nuclear reactors. However, it is a force of nature that still contains mysteries yet to be solved.
Researchers from the University of Washington, Seattle, or UW, and Los Alamos National Laboratory have used the Summit supercomputer at the Department of Energy’s Oak Ridge National Laboratory to answer one of fission’s biggest questions: What exactly happens during the nucleus’s “neck rupture” as it splits in two?
The resulting paper is published in the journal Physical Review Letters.
Researchers Takuma Nakamura, Kazuki Hashimoto, and Takuro Ideguchi of the Institute for Photon Science and Technology at the University of Tokyo have increased by 100-fold the measurement rate of Raman spectroscopy, a common technique for measuring the “vibrational fingerprint” of molecules in order to identify them.
As the measurement rate has been a major limiting factor, this improvement contributes to advancements in many fields that rely on identifying molecules and cells, such as biomedical diagnostics and material analytics. The findings were published in the journal Ultrafast Science.
Identifying various types of molecules and cells is a crucial step in both basic and applied science. Raman spectroscopy is a widely used measurement technique for this purpose. When a laser beam is projected onto molecules, the light interacts with the vibrations and rotations of molecular bonds, shifting the frequency of the scattering light. The scattering spectra thus measured is a molecule’s unique “vibrational fingerprint.”
By Chuck Brooks & Dr. Thomas A. Cellucci, MBA
Co-written by Chuck Brooks and Dr. Thomas A. Cellucci, MBA
Verticals that will be most impacted by innovative developments in technology and science are the disciplines of medicine, biotechnology, and health. Those industry verticals will see a profound growth of technological innovation in the near future.
Continue reading “Future Medicine: Physics, Biology, And AI Will Transform Human Health” »
Researchers have identified genes influencing muscle aging, including USP54, using AI analysis of gene expression data. These findings may lead to drug discovery and exercise-based interventions targeting muscle mass preservation.
I believe that the next generation of AI turing machines will be conscious turing machines that no longer read just tape but have their own consciousness that allows them to fix code or even be aware of its own code and fix it if it gets a virus.
Shared from Wolfram Cloud.
Protecting Human And Animal Health — Dr. Tristan Colonius, DVM — Chief Veterinary Officer & Deputy Director for Science Policy, Center for Veterinary Medicine (CVM), U.S. Food and Drug Administration (FDA)
Dr. Tristan Colonius, DVM is the Chief Veterinary Officer and Deputy Director for Science Policy at FDA’s Center for Veterinary Medicine (CVM — https://www.fda.gov/animal-veterinary).
Mike Kelly is President & Chief Executive Officer of NervGen Pharma Corp. (https://nervgen.com/), a clinical-stage biotech company dedicated to developing innovative treatments to enable nervous system repair in the settings of traumatic injury and disease.
NervGen’s lead drug candidate, NVG-291, is being evaluated in a Phase 1b/2a clinical trial in an initial target indication, spinal cord injury. NervGen has initiated preclinical evaluation of a new development candidate, NVG-300, in models of ischemic stroke, amyotrophic lateral sclerosis (ALS) and spinal cord injury.
The great George Church takes us through the revolutionary journey of DNA sequencing from his early groundbreaking work to the latest advancements. He discusses the evolution of sequencing methods, including molecular multiplexing, and their implications for understanding and combating aging.
We talk about the rise of biotech startups, potential future directions in genome sequencing, the role of precise gene therapies, the ongoing integration of nanotechnology and biology, the potential of biological engineering in accelerating evolution, transhumanism, the Human Genome Project, and the importance of intellectual property in biotechnology.
Continue reading “Synthetic Biology: George Church on Genome Sequencing and De-Extinction” »
A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome’s organization that directly affect gene regulation and expression.
