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New Graphene Technology Matures Brain Organoids Faster, May Unlock Neurodegenerative Insights

Researchers from University of California San Diego Sanford Stem Cell Institute have developed a novel method to stimulate and mature human brain organoids using graphene, a one-atom-thick sheet of carbon. Published in Nature Communications, the study introduces Graphene-Mediated Optical Stimulation (GraMOS), a safe, non-genetic, biocompatible, non-damaging way to influence neural activity over days to weeks. The approach accelerates brain organoid development — especially important for modeling age-related conditions like Alzheimer’s disease — and even allows them to control robotic devices in real time.

“This is a game-changer for brain research,” said Alysson Muotri, Ph.D., corresponding author, professor of pediatrics, and director of the UC San Diego Sanford Stem Cell Institute Integrated Space Stem Cell Orbital Research Center. “We can now speed up brain organoid maturation without altering their genetic code, opening doors for disease research, brain–machine interfaces and other systems combining living brain cells with technology.”

World’s first spinal cord transplant to take place in Israel, could allow patients to walk again

According to the World Health Organization, over 15 million people worldwide are living with spinal cord injuries, with the majority resulting from traumatic causes such as falls, road traffic accidents, and violence.

Currently, spinal cord injuries cannot be fully cured, so treatment focuses on stabilizing the patient, preventing further damage, and maximizing function. Emergency care often involves immobilizing the spine, reducing inflammation, and sometimes performing surgery to repair fractures or relieve pressure.

Rehabilitation includes physical and occupational therapy, as well as assistive devices like wheelchairs and braces. While experimental therapies—including stem cells and robotic devices—are being explored, no treatment yet reliably restores full spinal cord function.

Spinal cord injuries are one of the few human injuries where the body cannot naturally heal itself, and the tissue is both structurally complex and extremely sensitive.

“The spinal cord transmits electrical signals from the brain to all parts of the body. When it is severed by trauma—such as a car accident, a fall, or a combat injury—the chain is broken. Think of an electrical cable that has been cut: when the two ends no longer touch, the signal cannot pass, and the patient remains paralyzed below the injury,” explained Professor Tal Dvir, head of the Sagol Center for Regenerative Biotechnology and the Nanotechnology Center at Tel Aviv University, who is leading the effort. Dvir is also the chief scientist at Matricelf, the Israeli biotech company commercializing the technology.


Tel Aviv University announced on Wednesday that the surgery will take place in Israel, marking a historic milestone in regenerative medicine.

Ozempic teeth: Dentists warn of new GLP-1 side effect

Dentists warn they’re seeing cases of something nicknamed “Ozempic teeth.” Medications like Ozempic and Wegovy can lead to dry mouth because the active ingredient, semaglutide, affects the salivary glands, explains Adam Taylor, an anatomy professor at Lancaster University, in an article for The Conversation. The medications can also cause people to drink less water because they feel less thirsty.

Those factors combined increase the risk of cavities and gum disease, explained Dr. Rajpal Anjali, a cosmetic dentist at Beverly Hills Dental Arts.

To make things worse, some people also experience side effects like acid reflux and vomiting, further harming their tooth enamel.

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Tiny protein dismantles the toxic clumps behind Alzheimer’s

St. Jude Children’s Research Hospital. (2025, August 23). Tiny protein dismantles the toxic clumps behind Alzheimer’s. ScienceDaily. Retrieved August 23, 2025 from www.sciencedaily.com/releases/2025/08/250822073817.htm.

St. Jude Children’s Research Hospital. “Tiny protein dismantles the toxic clumps behind Alzheimer’s.” ScienceDaily. www.sciencedaily.com/releases/2025/08/250822073817.htm (accessed August 23, 2025).

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