Berkeley researchers have developed a proven mathematical framework for the compression of large reversible Markov chains—probabilistic models used to describe how systems change over time, such as proteins folding for drug discovery, molecular reactions for materials science, or AI algorithms making decisions—while preserving their output probabilities (likelihoods of events) and spectral properties (key dynamical patterns that govern the system’s long-term behavior).
While describing the dynamics of ubiquitous physical systems, Markov chains also allow for rich theoretical and computational investigation. By exploiting the special mathematical structure behind these dynamics, the researchers’ new theory delivers models that are quicker to compute, equally accurate, and easier to interpret, enabling scientists to efficiently explore and understand complex systems. This advance sets a new benchmark for efficient simulation, opening the door to scientific explorations once thought computationally out of reach.
The last few weeks in longevity science have been absolutely unreal. In this episode of Longevity Science News, Emmett Short breaks down 5 bombshell breakthroughs that could reshape the future of human health in 2026 — including an FDA-approved trial aiming to reverse cellular aging, cancer vaccines eliminating brain tumors in days, the regeneration of human teeth, one-shot GLP-1 Ozempic-style gene therapies, and a shocking new discovery linking gut bacteria to multiple sclerosis.
These aren’t sci-fi predictions — these are real developments happening right now in clinical trials, biotech labs, and cutting-edge medical research. If you care about anti-aging, regenerative medicine, epigenetic reprogramming, cancer immunotherapy, GLP-1 weight loss drugs, or the future of human lifespan, this is the episode you don’t want to miss.
Hume Band 20% off with Code LSN20 https://humehealth.com/pages/hume-ban… Huma Band Review: • Best Fitness Tracker For Longevity: Hume B… JOIN LSN Patreon for exclusive access to news, tips and a community of like minded longevity enthusiasts: https://www.patreon.com/user?u=29506604 ✅ Chapters 00:00 – The Longevity Science Explosion 00:48 Hume Band 20% Off 01:02 – Exclusive Interviews 01:43 Bombshell #1: FDA Approves Age Reversal Trial (Yamanaka Factors) 04:40 – Bombshell #2: Cancer’s Worst Month Ever (Vaccines + Immunotherapy) 09:19 – Bombshell #3: The Regeneration Revolution (Cartilage, Teeth, Liver) 11:30 – Bombshell #4: The One-Shot Ozempic Gene Therapy 12:25 – Bombshell #5: Gut Bacteria Linked to Multiple Sclerosis 13:55 – Final Recap + What Breakthrough Comes Next? Links in Script David Sinclair FDA Trial Tweet https://twitter.com/davidasinclair/status/2 … FDA Greenlights Age Reset Trial (Endpoints) https://endpoints.news/exclusive-fda–… Life Biosciences Epigenetic Reprogramming Video • Reprogramming Human Life — Michael Ringel… mRNA Brain Cancer Vaccine Tweet
… ⚠️ Disclaimer: This video is for educational and informational purposes only and does not constitute medical advice. Consult a qualified clinician before making health or treatment decisions. 🔗 EXCLUSIVE INTERVIEWS & BONUS CONTENT Get extended conversations, deep dives, and behind-the-scenes research ans a YouTube Member Patreon: 👉 / u29506604 YT Membership: 👉 / @longevitysciencenews PRODUCTION CREDITS ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Executive Producer – Keith Comito @Retromancers Host, Producer, Writer – Emmett Short @emmettshort
Full huma band review: • best fitness tracker for longevity: hume B…
An outbreak of the deadly Nipah virus in India has put many countries in Asia on high alert, given the fatality rate in humans can be between 40% and 75%.
Several countries, including Thailand, Malaysia, and Singapore, have introduced new screening and testing measures, after at least two people died of Nipah virus in the Indian state of West Bengal this month.
But what is Nipah virus, and how concerned should we be?
Here, Daniel H Cohn & team rescue the skeletal dysplasia phenotype of Trpv4 mutant mice—a new mouse model—using small molecule inhibition:
The figure: Reconstructed micro-CT images from WT and Co2a1-Cre/Trpv4p. R59H mutant mice showing reduction in the cervical angle (dashed red lines). The T1 vertebral body in the mutant was smaller and poorly mineralized.
2Actio Biosciences, San Diego, California, USA.
3Department of Orthopaedic Surgery, UCLA, Los Angeles, California, USA.
4Department of Nutritional Sciences, Dell Pediatric Research Institute, The University of Texas at Austin, Dell Medical School, Austin, Texas, USA.
Screening at an earlier age can help identify risk factors sooner, enabling preventive strategies that reduce long-term risk.
Screening for heart attack risk should be happening earlier for men, according to a new study that found the risk of cardiovascular disease starts climbing when men are in their mid-30s – significantly earlier than a similar trend is seen in women.
The US-based researchers behind the study followed the health of 5,112 people for an average of around 34 years. As the participants were healthy and aged 18–30 when the study started in the mid-1980s, the researchers could chart cases of cardiovascular disease (including strokes and heart failure) over time.
According to the data, 35 is the critical age when disparities between male and female cardiovascular disease risk start to appear. Most of the difference is driven by coronary heart disease (CHD), the most common cause of heart attacks, where fatty deposits clog up arteries, blocking blood flow.
Calculations show how the mysterious “magic numbers” that stabilize nuclear structures emerge naturally from nuclear forces—once these are described with appropriate spatial resolution.
Atomic nuclei have been studied for over a century, yet some of nuclear physics’ most basic questions remain unanswered: How many bound combinations of protons and neutrons, or isotopes, can exist? Where do the limits of nuclear existence lie? How are chemical elements synthetized in the Universe? Clues to solving these puzzles lie in the vast phenomenology of nuclear structure—the measured properties of tens of thousands of nuclear states, their decays, and their reactions. In this bedlam of information, patterns and irregularities in data provide crucial hints. One such irregularity was spotted as early as 1934 [1]: Nuclei containing specific numbers of protons and neutrons (2, 8, 20, 28, 50, 82…) are unexpectedly stable. These “magic numbers” (Fig.
Quantum chaos describes chaotic classical dynamical systems in terms of quantum theory, but simulations of these systems are limited by computational resources. However, one team seems to have found a way by leveraging error mitigation and specialized circuits on a 91-qubit superconducting quantum processor. Their results are published in Nature Physics.
While useful quantum simulations require an ability to eliminate errors, full quantum error correction requires large overheads in qubits and control. Previous work has gotten around this problem by simulating limited quantum many-body systems mostly at smaller scales or with integrable—or less chaotic—models.
The research team involved in the new study opted for a different method. Instead, they used error mitigation, which accepts noise and then corrects errors later, saving computational resources in the process.
