Light scattered in tissue usually ceases to be a useful source of information. But what if, instead of forcing it to travel along a single path, we allowed it to wander a little differently each time? Scientists from ICTER tested this seemingly risky idea and showed that a series of measurements that differ from one another can produce a clearer image than a single frame.
The new method was developed by scientists from the International Center for Translational Eye Research (ICTER), part of the Institute of Physical Chemistry of the Polish Academy of Sciences.
The team combined a mathematical model, computer simulations and experiments using optical coherence tomography (OCT). The researchers wanted to determine whether controlled changes in the way light is scattered could reduce speckle noise and make images less sensitive to selected optical aberrations.








