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Palo Alto Networks’ top exec calls AI Agents 2026’s biggest insider threat that an ‘impressed’ Salesforce CEO said may rename the company after
The TOI Tech Desk is a dedicated team of journalists committed to delivering the latest and most relevant news from the world of technology to readers of The Times of India. TOI Tech Desk’s news coverage spans a wide spectrum across gadget launches, gadget reviews, trends, in-depth analysis, exclusive reports and breaking stories that impact technology and the digital universe. Be it how-tos or the latest happenings in AI, cybersecurity, personal gadgets, platforms like WhatsApp, Instagram, Facebook and more; TOI Tech Desk brings the news with accuracy and authenticity.
Daniel Dennett: Philosophy, Robert Sapolsky, Human Clones, Free Will, Existence
The deepest dive into philosopher Daniel Dennett’s mind.
TIMESTAMPS:
00:00 — The Soul.
03:18 — Most Important Philosophical Question.
12:06 — Do Qualia Exist?
30:28 — Uploading Consciousness.
39:55 — Thinking Differently.
56:20 — Pragmatism.
1:01:06 — Robert Sapolsky.
1:12:57 — Philosophers and Scientists.
1:29:30 — Patterns and Emergence.
1:36:46 — Roger Penrose.
1:42:39 — Sailing Boats.
1:45:40 — Fictionalism.
1:51:12 — Coming Up With Concepts.
1:59:55 — Douglas Hofstadter.
2:05:30 — AI Alignment Problem.
2:11:31 — Q&A
NOTE: The perspectives expressed by guests don’t necessarily mirror my own. There’s a versicolored arrangement of people on TOE, each harboring distinct viewpoints, as part of my endeavor to understand the perspectives that exist.
THANK YOU: To Mike Duffey for your insight, help, and recommendations on this channel.
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We Thought This Particle Was Impossible To Measure!
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The #1 most-wanted particle in physics is the graviton, a quantum of gravity. If physicists were to prove that gravitons exist, they would unambiguously prove that Einstein’s theory is ultimately wrong and must be replaced by a more complete theory that gives quantum properties to space and time. In a recent paper, a physicist came up with an ingenious experiment that could prove that gravitons do exist. Let’s take a look.
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Teaching robots to map large environments
A robot searching for workers trapped in a partially collapsed mine shaft must rapidly generate a map of the scene and identify its location within that scene as it navigates the treacherous terrain.
Researchers have recently started building powerful machine-learning models to perform this complex task using only images from the robot’s onboard cameras, but even the best models can only process a few images at a time. In a real-world disaster where every second counts, a search-and-rescue robot would need to quickly traverse large areas and process thousands of images to complete its mission.
To overcome this problem, MIT researchers drew on ideas from both recent artificial intelligence vision models and classical computer vision to develop a new system that can process an arbitrary number of images. Their system accurately generates 3D maps of complicated scenes like a crowded office corridor in a matter of seconds.
Combination therapy for Burkitt’s lymphoma dramatically improves cure rates in mice
Burkitt’s lymphoma is a rare and aggressive blood cancer characterized by a translocation of the MYC gene. It occurs most often in children and young adults. In recent years, CAR-T cell therapy—often referred to as a “living drug” and administered as a single dose—has been approved for certain types of blood cancer, offering hope for a cure even in severe cases. However, its effectiveness against Burkitt’s lymphoma has been limited. Moreover, developing drugs that directly target MYC—the root cause of this cancer—has proven challenging for decades.
Recently, a study led by Dr. Hiroshi Kotani, Assistant Professor at Kanazawa University in collaboration with a scientist at Roswell Park Comprehensive Cancer Center in Buffalo, NY, U.S., revealed that a SUMOylation inhibitor can suppress MYC activity. Building on this finding, the research team investigated whether combining CAR-T therapy with the SUMOylation inhibitor TAK-981 could improve outcomes for Burkitt’s lymphoma. The research is published in Signal Transduction and Targeted Therapy.
The team first confirmed that the SUMOylation inhibitor effectively slowed the growth of Burkitt’s lymphoma cells and altered their signaling pathways. They then examined the inhibitor’s effect on CAR-T cells and discovered a dual role: While it initially activated the CAR-T cells in a way that could hinder long-term effectiveness, it also triggered a built-in “safety brake” mechanism. These insights suggested that using only a limited dose of the inhibitor could maximize the benefits of CAR-T therapy as a durable, living treatment.