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A Framework for Frontier AI and the Dawning of a New Age

Assorted web links to important articles.


This is a pivotal moment in human history. Artificial General Intelligence (AGI), a system that exhibits all the cognitive capabilities the brain has, is probably only a few short years away. When we look back on this time in the decades to come, I think we will realise we were standing in the foothills of the singularity — nothing less than the dawning of a new age for humanity.

I’ve spent my whole life working on AGI because I’ve always had a deep conviction that, if built and deployed responsibly, it would prove to be one of the most beneficial and transformative technologies ever invented. AGI cannot be compared to standard technological breakthroughs, not even ones as consequential as the internet or mobile — it is much more akin to the discovery of electricity or fire. If you stop to think about it, we’ve essentially found a way to make sand think. It’s miraculous.

The magnitude of this technology’s impact will be unprecedented, perhaps 10x of the Industrial Revolution at 10x the speed. It will help us solve some of the biggest problems society faces from accelerating drug discovery to developing new clean energy sources to creating novel advanced materials. We could even reach a point where resources are no longer the limiting factor for human progress, leading to an amazing new era of abundance.

Subcellular localization as a driver of protein function

Proteins can localize to multiple cellular compartments and some exhibit distinct functions depending on their location. This Review discusses the mechanisms of protein localization, the control of specialized protein functions through subcellular localization, and how mislocalization is involved in cancer, neurodegeneration and autoimmunity.

Dr. William Li

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Physicists create first room-temperature quantum material

Quantum materials could transform technologies ranging from powerful computers and ultrasecure communications to advanced energy systems. But there has always been one major obstacle.

Nearly all known quantum materials exhibit their remarkable properties only when cooled to temperatures close to absolute zero. At room temperature, heat creates constant atomic vibrations that overwhelm the delicate quantum behavior scientists are trying to harness. Keeping those vibrations in check requires bulky cryogenic refrigeration systems, making quantum materials powerful tools in the laboratory but difficult to translate into practical technologies.

In a study published in Nature, LSU physicists have developed the first room-temperature quantum material capable of distinguishing and transporting different quantum states of light, overcoming one of the biggest challenges in quantum materials research. Led by Associate Professor of Physics Omar S. Magaña-Loaiza, the work establishes a general design principle for engineering an entirely new class of quantum materials, opening new possibilities for quantum computing, secure communications, sensing technologies and advanced energy systems.

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