An interesting report on the phenomenon by which cells and organisms glow very faintly, primarily due to energy transitions during aerobic respiration. Speculation on biological functions and future applications are covered.
Ultra-weak ‘biophotons’ might be used to diagnose disease, or could even represent a new signalling mechanism in cells.
This hypothesis has led to a new “whole-brain” mathematical and computational model developed at the MOX Laboratory of the Department of Mathematics of Politecnico di Milano. The model is designed to describe in an integrated way the interaction between the spread of amyloid beta and the functioning of the cerebral vascular network. The aim is to provide a tool capable of simulating, on the scale of the whole organ, how small biological or vascular alterations can evolve over time and contribute to neurodegeneration. The model and the accompanying scientific study have been published in the prestigious scientific journal Computer Methods in Applied Mechanics and Engineering.
The model integrates two scales of analysis. On the one hand, it describes the dynamics of the production, transformation, diffusion and elimination of the healthy and pathological forms of amyloid beta. On the other, it describes blood flow through a “macroscopic” description of arteries, capillaries and veins, treating brain tissue as a porous medium perfused by blood vessels, through a macroscopic compartmental model. The two components are then connected to represent the possible mechanism of mutual reinforcement between protein accumulation and vascular dysfunction.
The simulations show a particularly relevant result: the brain can evolve into different states depending on the initial conditions. Small localised amounts of amyloid beta can be eliminated, allowing the system to return to a healthy state. Conversely, larger amounts can trigger a self-sustained spread of the pathology at brain scale.
Gen1Recomp gives the beloved Game Boy games a whole new look.
An international team of researchers from École Polytechnique, Collège de France and Helmholtz-Zentrum Dresden-Rossendorf (HZDR) has achieved a world first: the experimental realization of an all-optical photonic time crystal (PTC), a material whose optical properties can be strongly and periodically modulated over ultrafast timescales.
Published in Nature, this breakthrough uses HZDR’s TELBE superradiant terahertz source to drive the system into a new regime of light-matter interaction in the terahertz range. This discovery paves the way for ultrafast optical computing, new telecommunications systems and eventually new types of terahertz lasers.
Shaping the properties of light as it interacts with materials is the foundation of many discoveries and technological advances, including optical fibers for telecommunications, lasers as light sources and sensors for chemistry and biology.
What if glowing molecules could synchronize, much like fireflies flashing in unison? Researchers have discovered that molecules confined within tiny gold nanostructures can behave collectively, coordinating their interactions even under conditions where this was previously thought impossible. The finding challenges long standing assumptions about how optical coherence forms and opens new possibilities for highly sensitive sensors, molecular photonics, and future quantum technologies capable of operating at room temperature.
Optical coherence describes a state in which light—or the molecules producing it—behaves in a highly coordinated way. It is the principle behind technologies such as lasers, advanced imaging systems and quantum communication. Traditionally, scientists believed this kind of coordinated behavior required specially designed optical cavities that trap light for relatively long periods.
Researchers have developed and tested an infrared spectroscopy system that can rapidly detect chemical aerosols from a distance by using light reflected from common surfaces such as traffic signs, tree trunks or painted surfaces. The new method could make it possible to detect hazards without complicated instruments, helping improve safety and ease operations at industrial sites, public venues and other high-risk locations.
“Previously, many remote chemical detection systems have relied on placing a mirror or other highly reflective target in the field to bounce the laser signal back to the detector, which isn’t practical in many real-world situations,” said research team leader Tim Johnson from Pacific Northwest National Laboratory. “Our approach eliminates that requirement by using reflections from ordinary surfaces, allowing us to detect aerosolized chemicals from a distance without installing specialized equipment at the target location.”
In the journal Applied Optics, the researchers report results from laboratory tests using reflected infrared laser light from different surfaces. They showed that many nonmetallic surfaces could be used for aerosol and vapor detection at standoff distances of up to 11 meters (36 feet).
