Lifeboat Foundation: Safeguarding Humanity
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Ubiquitously present in plant life, coumarins, as a class of phenolic compounds, have multiple applications—in everyday life, in organic synthesis, in medicine and many others. Coumarins are well known for their broad spectrum of physiological effects. The specific structure of the coumarin scaffold involves a conjugated system with excellent charge and electron transport properties. The antioxidant activity of natural coumarins has been a subject of intense study for at least two decades. Significant research into the antioxidant behavior of natural/semi-synthetic coumarins and their complexes has been carried out and published in scientific literature.

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Furthermore, healthcare and life sciences are both booming sectors with regards to artificial intelligence applications. Many other companies are also working at the intersection of technology and biology, given the numerous challenges that are present in the fields of drug discovery and protein folding. For example, Deepmind and Isomorphic Labs have made immense progress with AlphaFold, another leading foundation model ecosystem to better understand protein folding. Meta created something similar with its ESM Metagenomic Atlas. Given the increasing rates of catastrophic disease and the rapidly evolving nature of pathogens, scientists in these sectors hope to use the best of the advancements in AI to help solve some of biology’s toughest challenges.

Indeed, the immense progress that has been made thus far has paved the way for monumental scientific inventions and developments to emerge in the years ahead. Undoubtedly, this work is just getting started.

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An international team has confirmed the discovery of a super-Earth orbiting in the habitable zone of a nearby sun-like star. The planet was originally detected two years ago by Oxford University scientist Dr. Michael Cretignier. This result, drawing on more than two decades of observations, opens a window to future studies of Earth-like exoplanets that may have conditions suitable for life.

The new planet, named HD 20,794D, has a mass six times that of Earth and orbits a star similar to our sun, located just 20 light years away. Its orbit places it within the habitable zone of the system, meaning it is at the right distance from its star to sustain liquid water on its surface, a key ingredient for life as we know it. The paper is published in the journal Astronomy & Astrophysics.

Dr. Cretignier first identified a candidate exoplanet signal in 2022, while analyzing archived data recorded by the HARPS (High Accuracy Radial Velocity Planet Searcher) spectrograph at the La Silla Observatory in Chile. This data analyzes the light absorbed and emitted by objects.

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A biomaterial that can mimic certain behaviors within biological tissues could advance regenerative medicine, disease modeling, soft robotics and more, according to researche(rs at Penn State.

Materials created up to this point to mimic tissues and extracellular matrices (ECMs) — the body’s biological scaffolding of proteins and molecules that surrounds and supports tissues and cells — have all had limitations that hamper their practical applications, according to the team. To overcome some of those limitations, the researchers developed a bio-based, “living” material that encompasses self-healing properties and mimics the biological response of ECMs to mechanical stress.

They published their results in Materials Horizons, where the research was also featured on the cover of the journal.

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Super Humanity — This documentary examines breakthroughs in neuroscience and technology. Imagine a future where the human brain and artificial intelligence connect.

Super Humanity (2019)
Director: Ruth Chao.
Writers: Ruth Chao, Paula Cons, Alphonse de la Puente.
Genre: Documentary, Sci-Fi.
Country: Portugal, Spain.
Language: English.
Release Date: December 27, 2019 (Spain)

Also Known As (AKA):
(original title) O Futuro da Mente.
El futuro de la mente.
Netherlands O Futuro da Mente.
Poland O Futuro da Mente.
Portugal O Futuro da Mente.
South Korea O Futuro da Mente.
Spain El futuro de la mente.
United States Mind Forward.

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Continue reading “Super Humanity | Transhumanism | Documentary” | >

NASA has significantly lowered the risk of near-Earth asteroid 2024 YR4 as an impact threat to Earth for the foreseeable future. When first discovered, asteroid 2024 YR4 had a very small, but notable chance of impacting our planet in 2032. As observations of the asteroid continued to be submitted to the Minor Planet Center, experts at NASA Jet Propulsion Laboratory’s (JPL’s) Center for Near-Earth Object Studies were able to calculate more precise models of the asteroid’s trajectory and now have found there is no significant potential for this asteroid to impact our planet for the next century. The latest observations have further reduced the uncertainty of its future trajectory, and the range of possible locations the asteroid could be on Dec. 22, 2032, has moved farther away from the Earth.

There still remains a very small chance for asteroid 2024 YR4 to impact the Moon on Dec. 22, 2032. That probability is currently 1.7%.

NASA will continue to observe asteroid 2024 YR4 with observatories funded by its Planetary Defense Coordination Office, and NASA’s James Webb Space Telescope will observe the asteroid in March to further gain insights about its size for scientific purposes.

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Using an approach called DNA origami, scientists at Caltech have developed a technique that could lead to cheaper, reusable biomarker sensors for quickly detecting proteins in bodily fluids, eliminating the need to send samples out to lab centers for testing.

“Our work provides a proof-of-concept showing a path to a single-step method that could be used to identify and measure and proteins,” says Paul Rothemund (BS ‘94), a visiting associate at Caltech in computing and mathematical sciences, and computation and neural systems.

A paper describing the work recently appeared in the journal Proceedings of the National Academy of Sciences. The lead authors of the paper are former Caltech postdoctoral scholar Byoung-jin Jeon and current graduate student Matteo M. Guareschi, who completed the work in Rothemund’s lab.

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