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Chasing the New DragonToxic Spongiform Leukoencephalopathy With Chronic Fentanyl Inhalation

Toxic spongiform: leukoencephalopathy with chronic fentanyl inhalation.


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Technological Disruption: Strategic Inflection Points From 2026

By Chuck Brooks


Quantum Computing and the Dismantling of Cryptographic Foundations Quantum technology may be the most transformative long-term influence on the horizon. Although large-scale, fault-tolerant quantum computers may remain years from realization, their expected influence is already transforming cybersecurity strategies. As quantum technology advances, the risk of “harvest now, decrypt later” assaults suggests that today’s encrypted sensitive data could become vulnerable in the future.

From 2026 to 2030, enterprises will increasingly recognize that cryptographic agility is vital. The move to post-quantum cryptography standards means that old systems, especially those in critical infrastructure, financial services, and government networks, need to be fully inventoried, evaluated, and upgraded.

New Experiment Sees Order Emerge from Chaos

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Physicists have theorized for decades that chaos doesn’t just destroy order, it can also create it. This could in turn mean that the laws of nature that make our universe the way it is could be emergent from chaos. In a recent study, physicists demonstrated order emerging chaos in an experiment. Let’s take a look.

Paper: https://www.nature.com/articles/s4156… mugs, posters and more: ➜ https://sabines-store.dashery.com/ 💌 Support me on Donorbox ➜ https://donorbox.org/swtg 👉 Transcript with links to references on Patreon ➜ / sabine 📝 Transcripts and written news on Substack ➜ https://sciencewtg.substack.com/ 📩 Free weekly science newsletter ➜ https://sabinehossenfelder.com/newsle… 👂 Audio only podcast ➜ https://open.spotify.com/show/0MkNfXl… 🔗 Join this channel to get access to perks ➜ / @sabinehossenfelder 📚 Buy my book ➜ https://amzn.to/3HSAWJW #science #sciencenews #physics #chaos.

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👉 Transcript with links to references on Patreon ➜ / sabine.
📝 Transcripts and written news on Substack ➜ https://sciencewtg.substack.com/
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#science #sciencenews #physics #chaos

Scientists May Have Discovered Why We Gained Consciousness

Of course, many people are familiar with the impressive mental abilities of the corvid family (crows, ravens, magpies, and jays), but even everyday avians like pigeons and chickens, would score surprisingly high on Newen and Montemayor’s consciousness scale. In one experiment known as the “mirror-audience test,” roosters were placed in an enclosure with a barrier separating them. When the shadow of a bird of prey was projected overhead, the test rooster warned its fellow conspecific (member of the same species), and when it was alone, it did not. Interestingly, when a mirror was placed in the enclosure to replace the previously see-through barrier, the test rooster did not warn its conspecific partner, even though the animal remained on the other side of the mirror, suggesting that the rooster was able to differentiate itself from other members of its own species.

“The presented results add to the growing body of evidence that consciousness may be present in many parts of the animal kingdom, across species that are phylogenetically distant from each other and have remarkably different brain structures,” the authors wrote. “Consciousness should not be deemed as an ‘all-or-nothing’ cognitive function but rather as a graded and multi-dimensional process.”

Multiomic Selection of Cancer-Testis Antigens as Precision Immuno-oncologic Targets in Head and Neck Cancer

CTAs, immune-privileged and aberrantly expressed in HNSCC tumors, were consistently undetectable in normal oral mucosa but highly enriched in malignant tissue. These findings inform the development of targeted adoptive cell therapies with minimized risk for off-tumor effects.


Question Can cancer-testis antigens (CTAs) be leveraged as precision immuno-oncologic targets for head and neck cancer?

Findings In this cross-sectional study including 33 samples from patients with head and neck squamous cell carcinoma (HNSCC), 23 testis-restricted and 44 testis-selective CTAs with tumor-specific expression were identified in both de novo and radiation-recurrent HNSCCs, validated across transcriptomic, genomic, and proteomic analyses. Of these, a core set of 14 CTAs were consistently detected across all datasets analyzed.

Meaning The CTAs identified in this study in both de novo and recurrent HNSCCs represent potential precision immuno-oncologic targets for adoptive cell therapeutics, such as T-cell receptor–engineered T-cell therapy.

Preliminary Evidence for Increased Histone Succinylation as a Potential Epigenetic Marker for Longevity

Elevated histone succinylation distinguishes offspring of long-lived individuals and aligns with enhanced nuclear functions, while succinate supplementation selectively improves motor performance in…

When will The Singularity happen? 🦾 Dr. Ben Goertzel

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Scientists Discover Protein That Could Treat Depression Through the Gut

New findings suggest that a protein known as Reelin could play a role in treating both “leaky gut” and severe depression. Could an injectable protein someday help address both “leaky gut” and severe depression? A new study from the University of Victoria (UVic), published in Chronic Stress, point

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