Large language models (LLMs) can store and recall vast quantities of medical information, but their ability to process this information in rational ways remains variable. A new study led by investigators from Mass General Brigham demonstrated a vulnerability in that LLMs are designed to be sycophantic, or excessively helpful and agreeable, which leads them to overwhelmingly fail to appropriately challenge illogical medical queries despite possessing the information necessary to do so.
Findings, published in npj Digital Medicine, demonstrate that targeted training and fine-tuning can improve LLMs’ abilities to respond to illogical prompts accurately.
“As a community, we need to work on training both patients and clinicians to be safe users of LLMs, and a key part of that is going to be bringing to the surface the types of errors that these models make,” said corresponding author Danielle Bitterman, MD, a faculty member in the Artificial Intelligence in Medicine (AIM) Program and Clinical Lead for Data Science/AI at Mass General Brigham.