By tracking the brain activity of volunteers estimating the duration of flashing lights, scientists have uncovered the sequential neural pathway that allows us to experience the passage of time.
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Long Non-Coding RNAs (lncRNAs) in Heart Failure: A Comprehensive Review
Heart failure (HF) is a widespread cardiovascular condition that poses significant risks to a wide spectrum of age groups and leads to terminal illness. Although our understanding of the underlying mechanisms of HF has improved, the available treatments still remain inadequate. Recently, long non-coding RNAs (lncRNAs) have emerged as crucial players in cardiac function, showing possibilities as potential targets for HF therapy. These versatile molecules interact with chromatin, proteins, RNA, and DNA, influencing gene regulation. Notable lncRNAs like Fendrr, Trpm3, and Scarb2 have demonstrated therapeutic potential in HF cases.
How Rockstar Fit Liberty City Into PS2’s Tiny Memory
Mark Brown from Game Maker’s Toolkit released a new video.
Clock Town Recreated Inside Perfect Dark By Dedicated Modder
Something you might have dreamed about 20 years ago.
World’s largest ever survey of physicists, results & reaction
What do physicists really think about the biggest mysteries in the universe?
In this video, leading voices in theoretical physics come together to unpack the results of the Big Mystery Survey—the largest survey ever conducted of professional physicists, prepared in collaboration with the American Physical Society’s Physics Magazine.\.
Human vs. Machine Consciousness | Imperial’s Murray Shanahan
An interview with Murray Shanahan on philosophy and AI consciousness.
For more on how you can get involved with Cosmos including roles we are hiring for & how to receive our grants, visit: https://johnathanbi.com/cosmos.
You can read the full transcript here: https://www.johnathanbi.com/p/transcript-for-interview-with-…ahan-on-ai.
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Further Reading:
Professor Shanahan’s book on Consciousness: https://amzn.to/42rdsT0 (affiliate)
Timestamps:
Brain histamine map connects genes to brain function and mental health
New research from King’s College London and the University of Porto has mapped the histamine system in the brain. Histamine, a molecule more commonly associated with allergies, plays a separate but poorly understood role in brain function. This study addresses this gap, building the first multiscale map of the histamine system that spans from genetics to behavior and related mental health conditions.
The findings provide a new framework for understanding how this often-overlooked chemical system contributes to brain function and could point toward new treatment strategies for histamine-related conditions such as depression, ADHD, and schizophrenia. The study is published in Nature Mental Health.
Histamine is a neurotransmitter, a molecule crucial for neurons to communicate with one another. Neuroscience research has classically focused on understanding other neurotransmitter systems such as dopamine and serotonin.