Lifeboat Foundation

Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated. This is achieved by cell extrusion programs, a checkpoint mechanism eliminating unwanted or harmful cells.

Researchers at the Max-Planck-Zentrum für Physik und Medizin (MPZPM), Institut Jacques Monod (CNRS, UP Cité, France) and Niels Bohr Institute (Denmark) have now demonstrated how physical signals can have an impact on the fate of extruding cells governing their death or survival. The results recently published in Nature Physics may establish novel paths for understanding tissue properties in both normal and pathological conditions.

Epithelia are dynamic and must constantly deal with cell renewal. Therefore, the removal of cells from a tissue, called apoptotic extrusion, occurs regularly. Its balance is key for epithelia homeostasis. In addition to this role in tissue homeostasis, cell extrusion is a major cause of tissue shape changes and tumor progression.

Throughout history, humanity has spun horrifying tales of sapient species beyond our own. From ghastly subhuman creatures dwelling in decrepit subterranean lairs to ghoulish humanoids bent on destruction, these lores have delighted and terrified us in equal measure. The medieval period was rife with legends of menacing beings lurking in the shadows, while centuries later, the Industrial Revolution ushered in scientific breakthroughs in anatomy and genetics. With this came a new question: could other sapient beings truly exist?

A scientist’s quest for microbes that produce purple pigments led her to the vibrant world of natural dyes, where biology and traditional artistry intertwine.

Is it possible to travel at 100 million miles an hour? Can we accomplish this with present day technology? Or is Interstellar travel a capability reserved for Alien Civilizations?
#nasa #uap #alien.

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