Researchers at the Massachusetts Institute of Technology (MIT) have discovered thousands of new proteins that protect bacteria from virus attacks using an AI system called DefensePredictor. What would usually take months of lab work can now be narrowed down to promising candidates in minutes.
Bacteria are under constant attack from viruses called bacteriophages. One of their most powerful defenses is CRISPR-Cas, a system that cuts up viral DNA to stop an infection and is now a valuable biotechnology tool for precisely editing genes in a lab.
Traditional methods of finding these defenses are long and laborious, equivalent to looking for a needle in a haystack. They involve searching for nearby known defensive genes and manually testing thousands of DNA fragments. But now, AI can take the strain.








