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Mechanisms underlying gut microbiota’s role in obesity

Energy absorption and short-chain fatty acids

Gut microbiota regulate energy metabolism through short-chain fatty acids (SCFAs) like acetate, butyrate, and propionate, which are products of fiber fermentation. While butyrate promotes insulin sensitivity and reduces inflammation, propionate may trigger overeating. Dysregulated SCFA production can contribute to obesity by enhancing energy absorption, disrupting appetite regulation, and promoting fat accumulation. Recent findings suggest that modulating SCFA production through dietary interventions can help regulate energy balance and improve metabolic health. Maintaining SCFA balance through diet or microbial modulation holds promise for obesity management.

High-Speed Cosmic Kick: A New Black Hole Discovery

A newly formed black hole recently received a high-speed “kick,” thanks to gravitational waves, which propelled it at about 5 million kilometers per hour—roughly 200 times the speed of light. This surprising discovery was made through data collected by gravitational wave observatories LIGO and Virgo. These observatories detected spacetime ripples produced by the coalescence of two black holes on January 29, 2020, revealing the large recoil effect.

For the first time, scientists have measured the early universe running in extreme slow motion, showing that time was five times slower just a billion years after the Big Bang. By studying nearly 200 quasars – hyperactive supermassive black holes at the centers of ancient galaxies – researchers have provided new evidence for Einstein’s theory of general relativity regarding an expanding universe.

The Mystery of Early Universe Time Dilation

Einstein’s general theory of relativity predicts that, as the universe expands, distant objects (and therefore the early universe) should appear to experience slower time. However, directly observing this has been challenging due to the vast distances and the faint signals coming from early cosmic phenomena. Previous research had established this dilation back to half the age of the universe using supernovae, but quasars have now pushed this further back to just a tenth of the universe’s age.

Cool biophysical modeling of the endoplasmic reticulum!

Active liquid network [ https://www.czbiohub.org/life-science/a-simple-model-for-an-…structure/](https://www.czbiohub.org/life-science/a-simple-model-for-an-…structure/)


Scientists use math and physics to address the mystery of just how the endoplasmic reticulum, an organelle essential to life at the cellular level, continually re-arranges itself.

Dive into the fascinating world of the Cori Cycle, also known as the lactic acid cycle! 🏋️‍♂️💡 In this video, we’ll explore how your body manages energy during intense exercise by recycling lactate from muscles back into glucose in the liver.
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Do you want to make your VRChat character more true to life? You can use motion capture gear to ensure the most realistic movement. There is plenty of equipment to choose from, and 3D character designer Yueou demonstrated one that might interest you: UDCAP, “silk-like” gloves for SteamVR that track your hand gestures pretty accurately.

While there is a little delay, such gloves could be a great addition to your setup. The creator, Udexreal, promises 15 hours of battery work, so you don’t have to worry about your virtual social life ending early. There are 12 sensors that cover all 15 finger joints, providing a total of 21 joint angles.

“Our sensors are foldable and highly flexible, blending seamlessly with fabric without causing any discomfort. They capture even the slightest stress, stretch, and bend, with a resolution of 0.01 degrees,” the creators say.