Reelin is a critical mechanistic link between neuronal activation and cocaine-induced behavioral adaptations.
Category: neuroscience – Page 79
Neuroscientists unveil digital ‘translator’ for brain studies
UCLA Health researchers have helped to develop a new digital toolbox to create a “common language” for brain network studies, potentially accelerating new discoveries and treatments for neurological and psychiatric conditions.
In a study recently published in the journal Nature Communications, the authors say the open-source software will help researchers worldwide overcome a longstanding hurdle in brain imaging research.
“As long as people have been interested in studying the brain, they have tried to map it out by answering a basic question: how many brain regions are there?” said study senior author Lucina Uddin, a UCLA Health Psychiatry and Biobehavioral Sciences Professor and Director of the UCLA Brain Connectivity and Cognition Laboratory.
Terahertz imaging reveals new views of internal cochlea structure
For the first time, researchers have shown that terahertz imaging can be used to visualize internal details of the mouse cochlea with micron-level spatial resolution. The non-invasive method could open new possibilities for diagnosing hearing loss and other ear-related conditions.
“Hearing relies on the cochlea, a spiral-shaped organ in the inner ear that converts sound waves into neural signals,” said research team leader Kazunori Serita from Waseda University in Japan. “Although conventional imaging methods often struggle to visualize this organ’s fine details, our 3D terahertz near-field imaging technique allows us to see small structures inside the cochlea without any damage.”
Terahertz radiation, which falls between microwaves and the mid-infrared region of the electromagnetic spectrum, is ideal for biological imaging because it is low-energy and non-harmful to tissues, scatters less than near-infrared and visible light and can pass through bone while also being sensitive to changes in hydration and cellular structure.
Bringing Philosophy to Science
In the first episode of the Insight Stream, hosted by Akhandadhi das and featuring Hridayananda das Goswami, we explore the fascinating intersection of science and philosophy. Presented by the Bhaktivedanta Institute, this episode delves into the boundaries of empirical knowledge, the role of metaphysics, and the timeless relevance of philosophical inquiry. Join us in this engaging discussion that challenges the dominance of physicalism and offers fresh perspectives on free will, consciousness, and the search for deeper truths.
The interplay of two genes illuminates how the large human brain evolved
Researchers from the German Primate Center—Leibniz Institute for Primate Research and the Max Planck Institute of Molecular Cell Biology and Genetics have discovered two specific genes that evolve exclusively in humans jointly influence the development of the cerebrum. They have thus provided evidence that these genes contribute together to the evolutionary enlargement of the brain.
The work has been published in Science Advances.
The results show that the two genes act in a finely tuned interplay: one ensures that the progenitor cells of the brain multiply more, while the other causes these cells to transform into a different type of progenitor cell—the cells that later form the nerve cells of the brain. In the course of evolution, this interplay has led to the human brain being unique in its size and complexity.
Atlas of brain’s mitochondria reveals high cognition areas supplied with more energy
Everything the brain does—from storing memories to interpreting sights to regulating emotions—requires energy, all produced by cellular organelles called mitochondria.
However, surprisingly little is known about the distribution and diversity of the brain’s tiny energy processors and how they influence brain health. For instance, how many mitochondria does the brain have? Are they uniformly distributed across the whole brain? Are all brain mitochondria the same? Do changes in the brain’s mitochondria affect mood, cognition, and the development of neurological and psychiatric conditions?
To begin answering these and other questions, Columbia University researchers have created MitoBrainMap, the first-ever atlas of the brain’s mitochondria.
The Hidden Heart Problem Quietly Shrinking Your Brain
Changes in the heart might mean more than just cardiovascular risk – they could also signal early shifts in brain health.
A large meta-analysis found that even subtle heart problems, like issues with how the heart pumps or relaxes, are linked to smaller brain volumes, particularly in areas related to memory.
Heart Issues May Signal Early Dementia Risk.