A new study reveals how uniquely wired human brains can perceive the world in strikingly similar ways.
“Cannabis is widely used, but its long-term effects on health remain poorly characterized,” said Sandra Sanchez-Roige, Ph.D., associate professor of psychiatry at UC San Diego School of Medicine and senior author of the study. The researchers were also interested in the relationship between genetics and traits that contribute to the development of cannabis use disorder, which can interfere with a person’s daily life.
“While most people who try cannabis do not go on to develop cannabis use disorder, some studies estimate that nearly 30% will,” said Sanchez-Roige. “Understanding the genetics of early-stage behaviors may help clarify who is at greater risk, opening the door to prevention and intervention strategies.”
The research team conducted a genome-wide association study (GWAS) analyzing relationships between cannabis use and genetic data provided by 131,895 23andMe research participants. They answered survey questions about whether or not they had ever used cannabis, and those who answered yes were also asked how frequently they used the drug.
“We’ve known for decades that genetic factors influence whether or not people will try drugs, how frequently they use those drugs, and the risk that they will become addicted to them,” said Abraham A. Palmer, Ph.D., professor and vice chair for basic research in the department of psychiatry at UC San Diego School of Medicine and co-author of the study. “Genetic tools like GWAS help us identify the molecular systems that connect cannabis use to brain function and behavior.”
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New research has found genetic associations between cannabis use and psychiatric, cognitive, and physical health. The findings could inform prevention and treatment strategies for cannabis use disorders.
Researchers at the University of Michigan have developed a mathematical model that reveals how our circadian rhythms can have dramatic impacts on how our bodies interact with medicines.
This could help doctors prescribe medicines to have the best intended effect by syncing the dosing up with the natural clocks of their patients.
“These findings provide a mechanistic basis for chronotherapeutics—optimizing drug efficacy by considering circadian timing,” said the new study’s author Tianyong Yao, an undergraduate researcher in the U-M Department of Mathematics. “This could improve treatment for conditions such as ADHD, depression and fatigue.”
Many marine species are no strangers to the depths of the oceans. Some animals, like certain sharks, tuna, or turtles, routinely perform extreme dives, whereas for other species, such behavior has been observed less frequently.
Now, an international team of researchers working in Peru, Indonesia, and New Zealand tagged oceanic manta rays—the largest species of ray—to learn more about the deep-diving behavior of these animals. They published their results in Frontiers in Marine Science.
“We show that, far offshore, oceanic manta rays are capable of diving to depths greater than 1,200 meters, far deeper than previously thought,” says first author Dr. Calvin Beale, who completed his Ph.D. at Murdoch University.
In the middle of the night, the world can sometimes feel like a dark place. Under the cover of darkness, negative thoughts have a way of drifting through your mind, and as you lie awake, staring at the ceiling, you might start craving guilty pleasures, like a cigarette or a carb-heavy meal.
Plenty of evidence suggests the human mind functions differently if awake at nighttime. Past midnight, negative emotions tend to draw our attention more than positive ones, dangerous ideas grow in appeal, and inhibitions fall away.
Some researchers think the human circadian rhythm is heavily involved in these critical changes in function, as they outline in a 2022 paper summarizing the evidence of how brain systems function differently after dark.
What happens when awareness grows too powerful for the universe that contains it?
SCP-3812 — also known as A Voice Behind Me — is the Foundation’s ultimate paradox: a being that rewrites existence every time it tries to understand itself. This speculative science essay explores the physics, metaphysics, and philosophy behind the phenomenon. From quantum observer effects to pancomputational cosmology, from the breakdown of time to the collapse of narrative itself, we ask the ultimate question:
What if consciousness doesn’t live inside reality, but creates it?
Join us as we explore:
- The origin of Sam Howell and post-mortem evolution of awareness.
- The science of unreality and the hierarchy of dimensions.
- Schizophrenia as multiversal cognition.
- Supersession, recursion, and the limits of containment.
- The final collapse of reality into pure perception.
If you love speculative science, existential philosophy, or cosmic horror wrapped in logic, this video will change the way you think about reality.