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Category: neuroscience – Page 21

Researchers at the CUNY Graduate Center have made a groundbreaking discovery in Alzheimer’s disease research, identifying a critical link between cellular stress in the brain and disease progression.

Their study focuses on microglia, the brain’s immune cells, which play dual roles in either protecting or harming brain health. By targeting harmful microglia through specific pathways, this research opens new avenues for potentially reversing Alzheimer’s symptoms and providing hope for effective treatments.

Key cellular mechanism driving alzheimer’s disease identified.

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Researchers from Kyushu University have developed an innovative technique to non-invasively measure two key signals, membrane voltage and intracellular calcium levels, at the same time, in neurons of awake animals. This new method offers a more complete understanding of how neurons function, revealing that these two signals encode different information for sensory stimuli. The research was published in Communications Biology on September 16, 2024.

Neurons are cells that act as the brain’s fundamental building blocks, transmitting information through . When a neuron receives a stimulus, changes in membrane voltage (the electrical charge across the neuron cell membrane) trigger the neuron to activate, causing rapid changes in membrane voltage to propagate along the neuron as an electrical signal. These changes in membrane voltage then lead to changes in intracellular calcium (calcium levels inside neurons).

Historically, measuring membrane voltage has involved invasive techniques using electrodes. As a non-invasive alternative, scientists have developed techniques to measure calcium activity using fluorescent proteins that are sensitive to calcium ions as sensors, providing an indirect proxy for neuron activity. However, these different methods mean that the two signals have almost always been studied separately, making it challenging to understand how they interact in real-time and to identify their distinct functions in living animals.

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The two professions associated with the lowest levels of death due to Alzheimer’s disease may be surprising.

Taxi and ambulance drivers were found to have the lowest proportion of deaths of more than 440 occupations that were considered in a new observation-based study from Massachusetts physicians.

Alzheimer’s disease is a type of dementia that affects memory, thinking, and behavior. It impacts millions of Americans and is one of the top 10 causes of death in the US.

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For the first time, researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM) to accurately model a patient’s response to CAR T cell therapy in real time. The organoid’s response to therapy mirrored the response of the actual tumor in the patient’s brain. That is, if the tumor-derived organoid shrunk after treatment, so did the patient’s actual tumor, according to new research from the Perelman School of Medicine, published in Cell Stem Cell.

Lab-grown tumors respond to cell therapy the same as tumors in the patients’ brains, according to researchers at Penn Medicine.

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What lies ahead in the aftermath of the Technological Singularity? Could the latest scientific breakthroughs refine our theological understanding? Do we live in a simulated multiverse? Are we alone in the universe? Can we achieve cybernetic immortality? When and by what means might we transcend our human condition? These profound inquiries are at the core of this enlightening volume.

#Theogenesis #CyberneticTheoryofMind #posthumanism #consciousness #evolution #cybernetics #theosophy #futurism #SyntellectHypothesis #PhilosophyofMind #QuantumCosmology #ComputationalPhysics #PressRelease #NewBookRelease #AudibleAudiobook #AmazonKindle

Ecstadelic Media Group releases THEOGENESIS: Transdimensional Propagation & Universal Expansion, The Cybernetic Theory of Mind series by Alex M. Vikoulov as an Audible audiobook in addition to a previously released Kindle eBook (Press Release, Burlingame, CA, USA, December 21, 2024 07.17 AM PST)

Continue reading “THEOGENESIS: Humanity’s Evolution Beyond the Technological Singularity” | >

In a paper published in the journal Neuroscience of Consciousness psychology researchers from the University of Technology Sydney (UTS) worked with 54 participants to examine the effects of surveillance on an essential function of human sensory perception – the ability to detect another person’s gaze.

Lead author, Associate Professor of neuroscience and behaviour Kiley Seymour, said previous research has established the effects on conscious behaviour when people know they are being watched, but the new study provided the first direct evidence that being watched also has an involuntary response.

“We know CCTV changes our behaviour, and that’s the main driver for retailers and others wanting to deploy such technology to prevent unwanted behaviour,” Associate Professor Seymour said.

However, we show it’s not only overt behaviour that changes – our brain changes the way it processes information.

We found direct evidence that being conspicuously monitored via CCTV markedly impacts a hardwired and involuntary function of human sensory perception – the ability to consciously detect a face.

Continue reading “Big brother: the effects of surveillance on fundamental aspects of social vision” | >

The innovation offers potential advancements in diagnosing conditions like arrhythmia and Alzheimer’s.

Researchers at MIT have unveiled a biosensing technique that uses tiny, wireless antennas to monitor electrical signals in biological systems with unprecedented precision.

By eliminating the need for wires and amplifiers, the innovation simplifies cellular studies, offering potential advancements in diagnosing conditions like arrhythmia and Alzheimer’s and enabling more targeted treatments.

Electrical signals are fundamental to cellular communication, yet traditional methods for measuring them are cumbersome and limited in scope.

Continue reading “MIT creates tiny antennas to track brain and heart disease signals” | >

Virtual reality headsets like the Meta Quest or Apple Vision Pro will be a Christmas gift in more than one home this year.

Now mice are getting in on the action.

Researchers have developed a set of VR goggles for lab mice for use in brain studies, according to a report published recently in the journal Nature Methods.

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A groundbreaking clinical trial has revealed that nerve-stimulating therapy can bring significant improvements to people with severe, treatment-resistant depression.

Nearly 500 participants, many unable to work due to their condition, received devices that stimulate the vagus nerve—a critical connection between the brain and body. After a year, those with activated devices reported measurable improvements in symptoms, quality of life, and daily functioning.

Breakthrough in Treatment-Resistant Depression.

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