Lifeboat Foundation

Neural microtissues derived from pluripotent stem cells (iPSCs) can replace dopaminergic neurons, the nerve cells that are lost in Parkinson’s disease, and restore motor function when grown into tiny capsules and transplanted into the brains of model rats, a study led by TreeFrog Therapeutics found.

“TreeFrog Therapeutics has overcome the most complex challenges of developing a successful treatment for Parkinson’s disease using our C-Stem platform technology and producing a therapy containing mature dopaminergic neurons with a unique 3D format that promotes cell survival post-graft with proven pre-clinical results,” Jens Schroeder, MD, PhD, TreeFrog’s chief medical officer, said in a company press release.

The study, “Bioreactor-produced iPSCs-derived dopaminergic neuron-containing neural microtissues innervate and normalize rotational bias in a dose-dependent manner in a Parkinson rat model,” was published in Neurotherapeutics.

https://youtube.com/channel/UC8Gtb6QcDOTbwcsDJo1bcGg

This little boy is really smart. I’m like in my 50’s this kid is barely 10, but much smarter than I am. Share and show him support. We need to have incentives for kids to thrive educationally. Props to the kids parents, they really raised an inspirational talent.

Sean is an aspiring brain and heart surgeon and he has created a name for it. He wants to be a “Neurocardio surgeon”. A word he created from Neurologist and Cardiologist. He is a STEM Educator Education Promotor/Advocate. He loves to learn and teach and wants to make the learning of science fun for all. Sean wants to create the awareness that science is not complex and can be seen in everything we do and in our everyday life. Sean is an advocate for positivity and shares motivation everywhere he goes. Sean is managed by his mom.

Biological components are less reliable than electrical ones, and rather than instantaneously receive the incoming signals, the signals arrive with a variety of delays. This forces the brain to cope with said delays by having each neuron integrate the incoming signals over time and fire afterwards, as well as using a population of neurons, instead of one, to overcome neuronal cells that temporarily don’t fire.

The human brain’s remarkably prolonged development is unique among mammals and is thought to contribute to our advanced learning abilities. Disruptions in this process may explain certain neurodevelopmental diseases.

Now, a team of researchers led by Prof. Pierre Vanderhaeghen (VIB-KU Leuven), together with scientists of Columbia University and Ecole Normale Supérieure has discovered a link between two genes, present only in human DNA, and a key gene called SYNGAP1, which is mutated in intellectual disability and autism spectrum disorders.

Their study, published in Neuron, provides a surprisingly direct link between human brain evolution and neurodevelopmental disorders.

New research in quantum entanglement could vastly improve disease detection, such as for cancer and Alzheimer’s disease.

Kyoto, Japan — Scanning your brain to decode the contents of your mind has been a subject of intense research interest for some time. As studies have progressed, scientists have gradually been able to interpret what test subjects see, remember, imagine, and even dream.

There have been significant limitations, however, beginning with a necessity to extensively catalog each subject’s unique brain patterns, which are then matched with a small number of pre-programmed images. These procedures require that subjects undergo lengthy and expensive fMRI testing.

Accidental Discovery in the Lab

The discovery happened unexpectedly during research on warty comb jellies (Mnemiopsis leidyi), also known as sea walnuts, in a lab at the University of Exeter. Researchers noticed that one jelly was missing from a tank, only to realize that a larger jelly was actually two individuals fused together. This accidental fusion occurred when the jellies sustained minor injuries. Excited by the finding, study lead author Kei Jokura immediately shared the discovery with other lab members.

The team then tested whether this fusion could be replicated. They injured 20 comb jellies by removing small sections of their bodies and placed them near each other. Out of the 20, nine pairs fused completely, typically within 24 hours. The merging process also affected their nervous systems, which synchronized rapidly. Researchers observed that the fused individuals reacted as one when poked, indicating a full integration of their neural functions.

Mycelium can plan and strategize based on their surroundings, even without brains.

Two participants entered a lucid dream and exchanged first ever ‘chat’ in dreams with specially designed equipment during REMspace experiment.